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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
26 Results for "
hydroxylated metabolite
" in MedChemExpress (MCE) Product Catalog:
Products (26)
26 Results for "hydroxylated metabolite" in MCE Product Catalog:
2
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24,25-Dihydroxy VD2 (24,25-Dihydroxy vitamin D2) is a hydroxylated metabolite and derivative of Vitamin D2 HY-76542 (HY-76542) .
Cat. No.: HY-W001160
CAS No.: 1953-54-4
Cat. No.: HY-W399311
CAS No.: 56806-74-7
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4-Hydroxyphenyl diphenyl phosphate is a hydroxylated metabolite of organophosphate flame retardant .
Synonyms: AR 00440993
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ONT-993 is an aliphatic hydroxylated metabolite. ONT-993 inhibits CYP2D6 (IC50=7.9 µM) and causes metabolism-dependent inactivation of CYP3A (KI=1.6 µM) .
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2,3,4-Trihydroxybenzophenone is a hydroxylated benzophenone UV filter with estrogenic activity. 2,3,4-Trihydroxybenzophenone is a quorum sensing inhibitor and an EC 1.14.18.1 (tyrosinase) inhibitor. 2,3,4-Trihydroxybenzophenone is also a human urinary metabolite, a rat metabolite and a drug metabolite .
Cat. No.: HY-136592
CAS No.: 53949-53-4
Synonyms: 1-OH IBU
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1-Hydroxy-ibuprofen (1-OH IBU) is a hydroxylated metabolite of Ibuprofen (HY-78131), a chiral compound that exists in enantiomeric forms and is found in human urine after Ibuprofen administration. 1-Hydroxy-ibuprofen is used in inflammation research .
Cat. No.: HY-149503
CAS No.: 2717115-85-8
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4-Hydroxy nebivolol (4-OH nebivolol) hydrochloride is an active β-blocking hydroxylated metabolite of Nebivolol (HY-B0203) .
Cat. No.: HY-W017519
CAS No.: 1196-57-2
Synonyms: Quinoxalin-2-one
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2-Quinoxalinol (2-hydroxyquinoxaline) is a 2-hydroxylated quinoxaline that possesses photocatalytic activity and interacts with various compounds, such as antioxidant vitamins and aromatic metabolites, including neurotransmitters and the pineal hormone melatonin .
Synonyms: 7α-Hydroxydehydroepiandrosterone; 3β,7α-Dihydroxy-Δ5-androsten-17-one
Category:
Cat. No.: HY-109502S
Cat. No.: HY-131543
CAS No.: 105012-15-5
Synonyms: RU 42698
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22-Hydroxy Mifepristone (RU 42698) is an orally active hydroxylated alcoholic metabolite with antiprogestational and antiglucocorticoidal activities, which contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. The relative binding affinity of 22-Hydroxy Mifepristone to the human glucocorticoid receptor is 48% .
Cat. No.: HY-W017519R
CAS No.: 1196-57-2
Synonyms: Quinoxalin-2-one (Standard)
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2-Quinoxalinol (2-hydroxyquinoxaline) is a 2-hydroxylated quinoxaline that possesses photocatalytic activity and interacts with various compounds, such as antioxidant vitamins and aromatic metabolites, including neurotransmitters and the pineal hormone melatonin .
Cat. No.: HY-N10475
CAS No.: 149947-22-8
Category:
Other Diseases Piperaceae Piper methysticum G.Forst. Phenols Polyphenols Plants Disease Research Fields
Target:
Cat. No.: HY-160624
CAS No.: 1331770-20-7
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CD 10899 is a hydroxylated metabolite of Volasertib (HY-12137). CD 10899 is pharmacologically active against Polo-like kinase 1 (PLK1) (IC50: 6 nM). Volasertib is an orally active, highly potent and ATP-competitive PLK1 inhibitor. CD 10899 can be used for research of cancer .
Cat. No.: HY-131543S
Synonyms: RU 42698-d6
Cat. No.: HY-124626
CAS No.: 147780-50-5
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(R)-(+)-Mequitazine is a histamine H1 receptor antagonist that mainly undergoes bio-transformation via human liver microsomes, resulting in hydroxylated and S-oxidized metabolites. (R)-(+)-Mequitazine competitively binds to the H1 receptors in gastrointestinal, vascular, and respiratory effect cells, thus blocking the endogenous activity of histamine. (R)-(+)-Mequitazine has an inhibitory effect on CYP3A-catalyzed midazolam 1’-hydroxylase. (R)-(+)-Mequitazine can be used in the study of various allergic diseases .
Cat. No.: HY-W001160R
CAS No.: 1953-54-4
Cat. No.: HY-150306A
CAS No.: 2137928-83-5
Synonyms: (Rac)-IM-250
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(Rac)-Adibelivir ((Rac)-IM-250) is a blood-brain barrier-penetrant HSV helicase-primase inhibitor and metabolic stabilizer with antiviral activity. (Rac)-Adibelivir is also effective against Acyclovir (HY-17422)-resistant strains, and its deuterated structure exhibits enhanced metabolic stability, reducing the formation of hydroxylated metabolites. (Rac)-Adibelivir prolongs in vivo half-life, reduces administration dosage, improves oral bioavailability, and achieves higher brain exposure in mice. (Rac)-Adibelivir can be used in the research of herpes simplex infection, herpes encephalitis and Alzheimer's disease .
Cat. No.: HY-150306C
CAS No.: 2954725-84-7
Synonyms: (Rac)-IM-250 hydrochloride
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Research Areas:
(Rac)-Adibelivir hydrochloride ((Rac)-IM-250 hydrochloride) is a blood-brain barrier-penetrant HSV helicase-primase inhibitor and metabolic stabilizer with antiviral activity. (Rac)-Adibelivir hydrochloride is also effective against Acyclovir (HY-17422)-resistant strains, and its deuterated structure exhibits enhanced metabolic stability, reducing the formation of hydroxylated metabolites. (Rac)-Adibelivir prolongs in vivo half-life, reduces administration dosage, improves oral bioavailability, and achieves higher brain exposure in mice. (Rac)-Adibelivir hydrochloride can be used in the research of herpes simplex infection, herpes encephalitis and Alzheimer's disease .
Cat. No.: HY-W740662
CAS No.: 64740-68-7
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1',4-Dihydroxymidazolam is a hydroxylated metabolite produced by cytochrome P450-mediated metabolism of midazolam in the liver .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
