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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
26 Results for "
ortho
" in MedChemExpress (MCE) Product Catalog:
Products (26)
26 Results for "ortho" in MCE Product Catalog:
3
3 Cited Publications
1
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4-Bromo-2-methoxyphenol (4-Bromoguaiacol) is a phenolic compound. 4-Bromo-2-methoxyphenol serves as a synthetic intermediate for the preparation of PT70. 4-Bromo-2-methoxyphenol acts as a precursor for generating masked ortho-benzoquinone (MOB) 6 .
Cat. No.: HY-W015600
CAS No.: 614-80-2
Synonyms: orthocetamol
Research Areas:
2-Acetamidophenol (Orthocetamol) is a regulator that targets ferroptosis and glutathione metabolic pathways, is the ortho-regioisomer of Paracetamol (HY-66005). 2-Acetamidophenol has anti-atherosclerotic activity, and inhibiting total cholesterol (TC) and triglyceride (TG) in a zebrafish hyperlipidemia model with IC50s for 30 μM and 40 μM, respectively. 2-Acetamidophenol upregulates the expression of glutathione synthesis-related genes (such as GCLC, GCLM, GSS) and iron ion transport genes (such as FPN1, FTH), reduces the accumulation of intracellular reactive oxygen species (ROS) and ferrous ions (Fe 2+), and enhances the activity of glutathione peroxidase GPX4, thereby inhibiting macrophage phagocytosis of oxidized low-density lipoprotein (ox-LDL) and foam cell formation .
Cat. No.: HY-124467
CAS No.: 39080-67-6
Synonyms: Ro 07-4065
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Difludiazepam (Ro 07-4065), a benzodiazepine derivative, is a GABAA receptor ligand with an IC50 of 4.1 nM. Difludiazepam binds to an allosteric site on the GABAA receptor to potentiate the receptor's response to GABA, reducing neuron excitability. Difludiazepam contains halogenated groups at the ortho position of its phenyl ring .
Cat. No.: HY-W015302
CAS No.: 88-21-1
Synonyms: Orthanilic acid; 2-Aminobenzenesulphonic acid
Target:
Synonyms: NSC 72345; ortho-tyrosine; o-DL-Tyrosine; o-Tyrosine
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Cat. No.: HY-W017469
CAS No.: 487-68-3
Synonyms: 2,4,6-Trimethylbenzaldehyde
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Synonyms: ABAO
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Research Areas:
2-Amino benzamidoxime (ABAO) acts as a bioconjugation reagent precursor and a fluorescent probe precursor. 2-Amino benzamidoxime contains an aniline group for imine activation of aldehydes, as well as a nucleophilic group (Nu:) located at the ortho position of the amine, which is responsible for intramolecular cyclization. 2-Amino benzamidoxime reacts with glyoxal at the N-terminus of phage-displayed peptide libraries. Derivatives of 2-Amino benzamidoxime can be used for protein bioconjugation. Derivatives of 2-Amino benzamidoxime serve as fluorescent probes .\n
Synonyms: HY366
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Thiotraniliprole (HY366) is an ortho formamidobenzamide insecticide that can be used for the synthesis of insecticidal combinations. Thiotraniliprole has potential applications in the prevention of lepidoptera pests, coleoptera pests, ants, and termites .
Cat. No.: HY-W015600R
CAS No.: 614-80-2
Synonyms: orthocetamol (Standard)
Research Areas:
2-Acetamidophenol (Standard) is the analytical standard of 2-Acetamidophenol. This product is intended for research and analytical applications. 2-Acetamidophenol (Orthocetamol) is a regulator that targets ferroptosis and glutathione metabolic pathways, is the ortho-regioisomer of Paracetamol (HY-66005). 2-Acetamidophenol has anti-atherosclerotic activity, and inhibiting total cholesterol (TC) and triglyceride (TG) in a zebrafish hyperlipidemia model with IC50s for 30 μM and 40 μM, respectively. 2-Acetamidophenol upregulates the expression of glutathione synthesis-related genes (such as GCLC, GCLM, GSS) and iron ion transport genes (such as FPN1, FTH), reduces the accumulation of intracellular reactive oxygen species (ROS) and ferrous ions (Fe 2+), and enhances the activity of glutathione peroxidase GPX4, thereby inhibiting macrophage phagocytosis of oxidized low-density lipoprotein (ox-LDL) and foam cell formation .
Cat. No.: HY-146332
CAS No.: 104260-73-3
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Research Areas:
Collagen-IN-1 (compound 3), an ortho-carbonyl hydroquinone derivative, is a selective inhibitor on collagen. Collagen-IN-1 inhibits agonist-induced platelet aggregation in a non-competitive manner with an IC50 value of 1.77 μM. Collagen-IN-1 reduces the expression of P-selectin, activation of glycoprotein IIb/IIIa, and release of adenosine triphosphate and CD63 from platelet. Collagen-IN-1 has the potential for platelet-related thrombosis diseases research .
Cat. No.: HY-W661499
CAS No.: 37338-80-0
Category:
Cat. No.: HY-W015600S
CAS No.: 122258-87-1
Synonyms: orthocetamol-d3
Cat. No.: HY-144577S
CAS No.: 265989-47-7
Cat. No.: HY-W585928
CAS No.: 35787-74-7
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Research Areas:
Di-o-cresyl phosphate is a urinary metabolite of tri-o-cresyl phosphate (HY-W011086), o,o,m-tricresyl phosphate, and o,o,p-tricresyl phosphate, and serves as a biomarker for monitoring exposure to ortho-isomers of tricresyl phosphate. Di-o-cresyl phosphate is not a metabolite of mono-o-tricresyl phosphate. Di-o-cresyl phosphate can be used in studies related to delayed neuropathy (OPIDN) .
Cat. No.: HY-158857
CAS No.: 2565592-49-4
Synonyms: o-Cannabinolquinone; ortho-Cannabinolquinone; o-CBNQ
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ortho-CBNQ (o-Cannabinolquinone) is an oxidative byproduct of Cannabidiol.
Cat. No.: HY-136346S
CAS No.: 265989-50-2
Cat. No.: HY-D2286
Cat. No.: HY-CE01896
CAS No.: 54429-77-5
Synonyms: ortho-coumaroyl-coenzyme A
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Ortho-coumaroyl-CoA (Ortho-coumaroyl-coenzyme A) is a coenzyme A derivative .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
