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Collagen-IN-1 (compound 3), an ortho-carbonyl hydroquinone derivative, is a selective inhibitor on collagen. Collagen-IN-1 inhibits agonist-induced platelet aggregation in a non-competitive manner with an IC50 value of 1.77 μM. Collagen-IN-1 reduces the expression of P-selectin, activation of glycoprotein IIb/IIIa, and release of adenosine triphosphate and CD63 from platelet. Collagen-IN-1 has the potential for platelet-related thrombosis diseases research.

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Collagen-IN-1 Chemical Structure

Collagen-IN-1 Chemical Structure

CAS No. : 104260-73-3

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Collagen-IN-1 Related Antibodies

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Description

Collagen-IN-1 (compound 3), an ortho-carbonyl hydroquinone derivative, is a selective inhibitor on collagen. Collagen-IN-1 inhibits agonist-induced platelet aggregation in a non-competitive manner with an IC50 value of 1.77 μM. Collagen-IN-1 reduces the expression of P-selectin, activation of glycoprotein IIb/IIIa, and release of adenosine triphosphate and CD63 from platelet. Collagen-IN-1 has the potential for platelet-related thrombosis diseases research[1].

Molecular Weight

230.26

Formula

C14H14O3
CAS No.
SMILES

OC(C=C1)=C2[C@@]3(CCCC3)C=CC4=O[H]OC1=C42
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Purity & Documentation
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Collagen-IN-1 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Collagen-IN-1104260-73-3Othersortho-carbonyl hydroquinonecollagenplatelet aggregationP-selectinglycoprotein IIb/IIIaadenosine triphosphateCD63thrombosisInhibitorinhibitorinhibit

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