104260-73-3
104260-73-3
Chemical Structure
Collagen-IN-1
- CAS No.: 104260-73-3
- Formula:C14H14O3
- Molecular Weight:230.26
InChIKey: JJLNDTZUFGLLGI-UHFFFAOYSA-N
SMILES: OC(C=C1)=C2[C@@]3(CCCC3)C=CC4=O[H]OC1=C42
Biological Activity: Collagen-IN-1 (compound 3), an ortho-carbonyl hydroquinone derivative, is a selective inhibitor on collagen. Collagen-IN-1 inhibits agonist-induced platelet aggregation in a non-competitive manner with an IC50 value of 1.77 μM. Collagen-IN-1 reduces the expression of P-selectin, activation of glycoprotein IIb/IIIa, and release of adenosine triphosphate and CD63 from platelet. Collagen-IN-1 has the potential for platelet-related thrombosis diseases research[1].
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Collagen-IN-1 | Collagen-IN-1 (compound 3), an ortho-carbonyl hydroquinone derivative, is a selective inhibitor on collagen. Collagen-IN-1 inhibits agonist-induced platelet aggregation in a non-competitive manner with an IC50 value of 1.77 μM. Collagen-IN-1 reduces the expression of P-selectin, activation of glycoprotein IIb/IIIa, and release of adenosine triphosphate and CD63 from platelet. Collagen-IN-1 has the potential for platelet-related thrombosis diseases research. | |||||||||||||||||||||
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