ortho-Topolin riboside
ortho-Topolin riboside is a naturally occurring cytokinin secreted from Populus x robusta leaves after sunrise. ortho-Topolin riboside has shown unique cytotoxic activity against NCI60 cell lines compared with the activity of other cytokinins.ortho-Topolin riboside induced differentiation through inhibition of STAT3 signaling in acute myeloid leukemia HL-60 cells.
For research use only. We do not sell to patients.
- CAS No.: 50868-58-1
- Formula: C17H19N5O5
- Molecular Weight:373.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 50868-58-1
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Molecular Weight 373.36
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Formula C17H19N5O5
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SMILES
OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C(N=CN=C32)NCC4=CC=CC=C4O)O1)O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Wang L, Cheng J, Lin F, Liu S, Pan H, Li M, Li S, Li N, Li W. Ortho-Topolin Riboside Induced Differentiation through Inhibition of STAT3 Signaling in Acute Myeloid Leukemia HL-60 Cells. Turk J Haematol. 2019 Aug 2;36(3):162-168. [Content Brief]
[2]. Voller J, Beres T, Zatloukal M, Kaminski PA, Niemann P, Dolezal K, Dzubak P, Hajduch M, Strnad M. The natural cytokinin 2OH3MeOBAR induces cell death by a mechanism that is different from that of the “classical” cytokinin ribosides. Phytochemistry. 2017;136:156–164. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)