Ortho-hydroxy atorvastatin-d5 calcium
Based on 1 Customer Validation
Ortho-hydroxy atorvastatin-d5 calcium is the deuterium labeled Ortho-hydroxy atorvastatin (HY-144577). Ortho-hydroxy atorvastatin is the metabolic of Atorvastatin (HY-B0589).
For research use only. We do not sell to patients.
- CAS No.: 265989-47-7
- Formula: C33H30D5FN2O6.1/2Ca
- Molecular Weight:599.71
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 265989-47-7
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Unlabeled Cas 265989-46-6
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Molecular Weight 599.71
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Formula C33H30D5FN2O6.1/2Ca
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SMILES
OC1=C(NC(C2=C(N(C(C3=CC=C(F)C=C3)=C2C4=C(C([2H])=C(C([2H])=C4[2H])[2H])[2H])CC[C@H](C[C@H](CC(O)=O)O)O)C(C)C)=O)C=CC=C1.[Ca].[1/2]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Zhou Y, et al. Development and validation of a liquid chromatography-tandem mass spectrometry method for simultaneous determination of amlodipine, atorvastatin and its metabolites ortho-hydroxy atorvastatin and para-hydroxy atorvastatin in human plasma and its application in a bioequivalence study. J Pharm Biomed Anal. 2013 Sep;83:101-7. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ortho-hydroxy atorvastatin-d5 calcium Related Classifications
HY-144577S Related Classifications
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