Atorvastatin

Atorvastatin purchased from MedChemExpress. Usage Cited in: Nat Metab. 2025 Oct;7(10):2142-2164. [Abstract]

Customer Validation
Representative histogram and quantification of normalized MHC I membrane levels determined by flow cytometry (stained for anti-HLA-A, anti-HLA-B and anti-HLA-C) in response to indicated treatment conditions in iAstrocytes (N = 4–6; three (control and cholesterol) or two (Atorvastatin hemicalcium salt) independent experiments from two isogenic sets. Data are shown as the mean. *P < 0.05 (two-sided one-sample t-test for cholesterol and atorvastatin versus 1).

Atorvastatin purchased from MedChemExpress. Usage Cited in: Nat Metab. 2025 Oct;7(10):2142-2164. [Abstract]

Customer Validation
Secreted Il-6 levels in medium of ApoE3 iAstrocytes that were pretreated with or without exogenous Cholesterol (10 μM) or Atorvastatin hemicalcium salt (0.5 μM) for 1 h before 24-h cotreatment with increasing doses of TNF, IL-1α and C1q.

Atorvastatin purchased from MedChemExpress. Usage Cited in: Environ Sci Technol Lett. 2025 Apr 8.

Customer Validation
The hCMEC-D3 cells were exposed to 0.01 μM 77PD-Q for 24 h in the presence or absence of 0.3 μM Atorvastatin (0.3 μM, 24 h).

Atorvastatin purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2025 Oct:146:157128. [Abstract]

Customer Validation
ApoE^-/- mice were administrated with high-fat-diet accompanied by MFEVLPs (5 or 50 μg/d, i.p) or Atorvastatin (10 mg/kg/day, i.g) for 12 weeks.

Atorvastatin purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2024 Jul 5:e2403451. [Abstract]

Customer Validation
Representative images of p-AKT1 staining of liver sections of the DMSO, Simvastatin and Atorvastatin hemicalcium salt (20 mg/kg, 3 days, atorvastatin with HFD)‐treated mice.

Atorvastatin purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2024 Jul 5:e2403451. [Abstract]

Customer Validation
Western blotting of PAQR9 in mouse primary hepatocytes under the treatment of DMSO, Simvastatin (Sim), Atorvastatin hemicalcium salt (Ator, 10 mmol/L, 24-48 h) and Rosuvastatin (Rosu).

Atorvastatin purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2024 Jul 5:e2403451. [Abstract]

Customer Validation
The top 20 predicted transcription factors of differentially expressed genes under Atorvastatin hemicalcium salt treatment. The gene expression data were from GEO datasets GSE24188 and the TF prediction was by ChEA3. The bar showed rank score and the line showed the number of overlapped genes.

Atorvastatin purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2023 Dec 25;8(1):457. [Abstract]

Customer Validation
EGFRvIII-high U87 cells were cocultured with EGFRvIII-CAR-T cells and treated with Atorvastatin (5 μM, 3 days) or Cytochalasin D (10 μg/mL, 1 day). Immunoblotting of magnetically separated cells showed that both drugs alleviated CAR molecule transfer (representative of three independent experiments).

Atorvastatin purchased from MedChemExpress. Usage Cited in: Cancer Lett. 2023 Jan 1:552:215976. [Abstract]

Customer Validation
Panc-1 and MIA PaCa-2 cells were treated with Atorvastatin (20 μM or 50 μM) for 24 h. FOXM1 and mutant p53 protein levels were measured in different treatment groups.

Atorvastatin purchased from MedChemExpress. Usage Cited in: Oncogene. 2022 Dec;41(49):5266-5278. [Abstract]

Customer Validation
ATP assay. The combination of Atorvastatin (2.5, 5, 10, 20 μM; 48 h) and SR1078 synergistically inhibits CRC cell viability.

Atorvastatin purchased from MedChemExpress. Usage Cited in: Mol Cell. 2021 Jul 1;81(13):2736-2751.e8. [Abstract]

Customer Validation
Tumor volumes of indicated patient-derived xenografts (PDXs) treated with Atorvastatin (40 mg/kg, i.p., every two days for 30 days).

Atorvastatin purchased from MedChemExpress. Usage Cited in: Endocrinology. 2018 May 1;159(5):2008-2021. [Abstract]

Customer Validation
Male C57BL/6 mice are intragastrically treated with Atorvastatin (0.1 mg/kg/day) and placebo for 10 weeks in the presence of HFD after 10-week-HFD feeding and then sacrificed for sample collection. H&E and oil red O staining of frozen liver sections.