2. Metabolic Enzyme/Protease
  3. HMG-CoA Reductase (HMGCR)
  4. Atorvastatin (lysine)

Atorvastatin lysine is an inhibitor of HMG-CoA reductase. Atorvastatin lysine can be used to study hypercholesterolemia and mixed hyperlipidemia.

For research use only. We do not sell to patients.

CAS No. : 609843-23-4

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Atorvastatin (lysine) Related Antibodies

Top Publications Citing Use of Products

53 Publications Citing Use of MCE Atorvastatin (lysine)

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Cell Proliferation/Viability Assay

    Atorvastatin (lysine) purchased from MedChemExpress. Usage Cited in: Environ Sci Technol Lett. 2025 Apr 8.

    The hCMEC-D3 cells were exposed to 0.01 μM 77PD-Q for 24 h in the presence or absence of 0.3 μM Atorvastatin (0.3 μM, 24 h).

    Atorvastatin (lysine) purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2025 Oct:146:157128.  [Abstract]

    ApoE-/- mice were administrated with high-fat-diet accompanied by MFEVLPs (5 or 50 μg/d, i.p) or Atorvastatin (10 mg/kg/day, i.g) for 12 weeks.

    Atorvastatin (lysine) purchased from MedChemExpress. Usage Cited in: Signal Transduct Target Ther. 2023 Dec 25;8(1):457.  [Abstract]

    EGFRvIII-high U87 cells were cocultured with EGFRvIII-CAR-T cells and treated with Atorvastatin (5 μM, 3 days) or Cytochalasin D (10 μg/mL, 1 day). Immunoblotting of magnetically separated cells showed that both drugs alleviated CAR molecule transfer (representative of three independent experiments).

    Atorvastatin (lysine) purchased from MedChemExpress. Usage Cited in: Cancer Lett. 2023 Jan 1:552:215976.  [Abstract]

    Panc-1 and MIA PaCa-2 cells were treated with Atorvastatin (20 μM or 50 μM) for 24 h. FOXM1 and mutant p53 protein levels were measured in different treatment groups.

    Atorvastatin (lysine) purchased from MedChemExpress. Usage Cited in: Oncogene. 2022 Dec;41(49):5266-5278.  [Abstract]

    ATP assay. The combination of Atorvastatin (2.5, 5, 10, 20 μM; 48 h) and SR1078 synergistically inhibits CRC cell viability.

    Atorvastatin (lysine) purchased from MedChemExpress. Usage Cited in: Mol Cell. 2021 Jul 1;81(13):2736-2751.e8.  [Abstract]

    Tumor volumes of indicated patient-derived xenografts (PDXs) treated with Atorvastatin (40 mg/kg, i.p., every two days for 30 days).

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    Description

    Atorvastatin lysine is an inhibitor of HMG-CoA reductase. Atorvastatin lysine can be used to study hypercholesterolemia and mixed hyperlipidemia[1].

    Molecular Weight

    704.83

    Formula

    C39H49FN4O7
    CAS No.
    SMILES

    NCCCC[C@H](N)C(O)=O.O=C(C1=C(C(C)C)N(CC[C@@H](O)C[C@@H](O)CC(O)=O)C(C2=CC=C(C=C2)F)=C1C3=CC=CC=C3)NC4=CC=CC=C4
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.
    Purity & Documentation
    References
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    Atorvastatin (lysine) Related Classifications

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Atorvastatin (lysine)609843-23-4HMG-CoA Reductase (HMGCR)HMG-CoA reductase inhibitorhypercholesterolemiamixed hyperlipidemiaInhibitorinhibitorinhibit

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