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Results for "

plant saponin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (7) Autophagy (4) Bacterial (2) Biochemical Assay Reagents (1) DNA/RNA Synthesis (1) Drug Derivative (1) Drug Metabolite (1) Environmental Pollutants (1) Fatty Acid Synthase (FASN) (2) Fungal (2) GLUT (1) HIV (1) Insecticide (1) JNK (1) LXR (2) NF-κB (1) Nucleoside Antimetabolite/Analog (1) PIN1 (1) Reactive Oxygen Species (ROS) (3) Reference Standards (5) Xanthine Oxidase (1)
By Research Areas:	Cancer (7) Cardiovascular Disease (2) Infection (1) Inflammation/Immunology (6) Metabolic Disease (7) Neurological Disease (1)

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Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-100597

Saponins 5 Publications Verification saponin	Environmental Pollutants Bacterial Fungal	Inflammation/Immunology
Saponins (Saponin) is a class of chemical compound of glycosides found in particular abundance in various plant species. In plants, Saponins may serve as anti-feedants, and to protect the plant against microbes and fungi .

HY-N0124

Dioscin Maximum Cited Publications 11 Publications Verification Collettiside III; CCRIS 4123	Autophagy Apoptosis	Cardiovascular Disease Cancer
Dioscin (CCRIS 4123; Collettiside III) is a natural plant-derived steroidal saponin that has good anti-cancer activity against a variety of cancer cells. Dioscin causes DNA damage and induces apoptosis in HeLa and SiHa cells. Dioscin regulates ROS-mediated DNA damage and mitochondrial signaling pathways, exerting anticancer activity .

HY-N0706

Gracillin 2 Publications Verification	Apoptosis Autophagy	Cancer
Gracillin is a steroidal saponin that can be extracted from the roots of the plant and has anti-tumor properties. Gracillin can induce cancer cell apoptosis and autophagy .

HY-N2078

Yamogenin Neodiosgenin	LXR Reactive Oxygen Species (ROS) Apoptosis Fatty Acid Synthase (FASN)	Metabolic Disease
Yamogenin (Neodiosgenin) is a diastereomer of diosgenin. Yamogenin antagonizes the activation of the liver X receptor (LXR) in luciferase ligand assay. Yamogenin inhibits triacylglyceride (TG) accumulation through the suppression of gene expression of fatty acid synthesis in HepG2 hepatocytes. Yamogenin is a steroidal saponin that can be obtained from plant species with in vitro cytotoxicity, antioxidant, and antimicrobial properties. Yamogenin induces cell death via the extrinsic and intrinsic way of apoptosis. Yamogenin inhibits protein denaturation with an IC₅₀ of 1421.92 μg/mL. Yamogenin can be studied in research on gastric cancer .

HY-N6911

Licorice-saponin H2 (18β,20α)-Glycyrrhizic acid	Others	Metabolic Disease
Liquorice-saponin H2 ((18β,20α)-Glycyrrhizic acid) is a type of triterpenoid oligosaccharide glycoside found in the Glycyrrhiza genus. Liquorice-saponin H2 accumulates more in the roots of licorice plants under salt stress conditions, suggesting that it may play a role in plant stress resistance .

HY-N1439

Methyl gypsogenin-3-O-glucuronide Gypsogenin-3-O-(6-O-methyl)-glucoside	Others	Inflammation/Immunology
Methyl gypsogenin-3-O-glucuronide (Gypsogenin-3-O-(6-O-methyl)-glucoside) is a ubiquitous saponin precursor in plants of the genus Gypsophila .

HY-N6924

Zingibroside R1 1 Publications Verification	HIV PIN1 Fungal GLUT Reactive Oxygen Species (ROS)	Infection Neurological Disease Metabolic Disease Cancer
Zingibroside R1 is an orally active triterpene saponin with multiple biological activities including antioxidant, anti-inflammatory, antiviral, and metabolic regulatory properties. Zingibroside R1 reduces the expression of PIN family members, inhibits the expression of PLT1/PLT2, WOX5, SHR, and SCR, disrupts auxin transport and distribution, triggers plant ROS responses, and inhibits root growth. Zingibroside R1 extends the lifespan of Caenorhabditis elegans, enhances its heat stress resistance, and improves its motor ability. Hydrogel derivatives of Zingibroside R1 inhibit the proliferation of Candida albicans by binding to its β-1,3-glucan and exhibit antifungal activity. Zingibroside R1 inhibits GLUT1-mediated uptake and alleviates liver injury. Zingibroside R1 can be used in research related to neurodegenerative diseases, vulvovaginal candidiasis, acute liver injury, Ehrlich ascites tumor and HIV-1 infection .

HY-N0124R

Dioscin (Standard) Collettiside III (Standard); CCRIS 4123 (Standard)	Reference Standards Autophagy Apoptosis	Cardiovascular Disease Cancer
Dioscin (Standard) is the analytical standard of Dioscin. This product is intended for research and analytical applications. Dioscin (CCRIS 4123; Collettiside III) is a natural plant-derived steroidal saponin that has good anti-cancer activity against a variety of cancer cells. Dioscin causes DNA damage and induces apoptosis in HeLa and SiHa cells. Dioscin regulates ROS-mediated DNA damage and mitochondrial signaling pathways, exerting anticancer activity .

HY-N2205

Esculentoside H 2 Publications Verification	NF-κB JNK	Cancer
Esculentoside H (EsH) is a saponin isolated from the root extract of perennial plant Phytolacca esculenta . Esculentoside H (EH) has anti-tumor activity, the mechanism is related to the capacity for TNFrelease . Esculentoside H (EsH) suppresses colon cancer cell migration through blockage of the JNK1/2 and NF-κB signaling-mediated matrix metalloproteinases-9 (MMP-9) expression .

HY-N10414

Primulic acid I Primulasaponin 1; Primula acid I	Bacterial	Others
Primulic acid I (Primulasaponin 1) is a plant-derived triterpenoid saponin with one sugar chain (monodesmoid) .

HY-N7974

Kizuta saponin K11	Others	Others
Kizuta saponin K11 is a saponin found in the leaves of Kalopanax pictum var. maximowiczii, a Korean medicinal plant .

HY-N6911B

Licorice-saponin H2 ammonium (18β,20α)-Glycyrrhizic acid ammonium	Others	Metabolic Disease
Liquorice-saponin H2 ((18β,20α)-Glycyrrhizic acid) ammonium is a type of triterpenoid oligosaccharide glycoside found in the Glycyrrhiza genus. Liquorice-saponin H2 ammonium accumulates more in the roots of licorice plants under salt stress conditions, suggesting that it may play a role in plant stress resistance .

HY-N10414R

Primulic acid I (Standard) Primulasaponin 1 (Standard); Primula acid I (Standard)	Insecticide Reference Standards	Others
Primulic acid I (Standard) is the analytical standard of Primulic acid I. This product is intended for research and analytical applications. Primulic acid I (Primulasaponin 1) is a plant-derived triterpenoid saponin with one sugar chain (monodesmoid) .

HY-N9324

Ilexoside O	Xanthine Oxidase	Inflammation/Immunology
Ilexoside O is a triterpene saponin isolated from the roots of Ilex pubescens. Ilexoside O exhibits weak xanthine oxidase (XOD) inhibitory activity (IC₅₀=53.05 μM) .

HY-N0706R

Gracillin (Standard)	Reference Standards Apoptosis Autophagy	Cancer
Gracillin (Standard) is the analytical standard of Gracillin. This product is intended for research and analytical applications. Gracillin is a steroidal saponin that can be extracted from the roots of the plant and has anti-tumor properties. Gracillin can induce cancer cell apoptosis and autophagy .

HY-16445BR

CNDAC hydrochloride (Standard)	Reference Standards Nucleoside Antimetabolite/Analog Drug Metabolite Apoptosis DNA/RNA Synthesis	Cancer
Dioscin (Standard) is the analytical standard of Dioscin. This product is intended for research and analytical applications. Dioscin (CCRIS 4123; Collettiside III) is a natural plant-derived steroidal saponin that has good anti-cancer activity against a variety of cancer cells. Dioscin causes DNA damage and induces apoptosis in HeLa and SiHa cells. Dioscin regulates ROS-mediated DNA damage and mitochondrial signaling pathways, exerting anticancer activity .

HY-N2078R

Yamogenin (Standard) Neodiosgenin (Standard)	Reference Standards LXR Apoptosis Fatty Acid Synthase (FASN) Reactive Oxygen Species (ROS)	Metabolic Disease
Yamogenin (Standard) is the analytical standard of Yamogenin. This product is intended for research and analytical applications. Yamogenin (Neodiosgenin) is a diastereomer of diosgenin. Yamogenin antagonizes the activation of the liver X receptor (LXR) in luciferase ligand assay. Yamogenin inhibits triacylglyceride (TG) accumulation through the suppression of gene expression of fatty acid synthesis in HepG2 hepatocytes. Yamogenin is a steroidal saponin that can be obtained from plant species with in vitro cytotoxicity, antioxidant, and antimicrobial properties. Yamogenin induces cell death via the extrinsic and intrinsic way of apoptosis. Yamogenin inhibits protein denaturation with an IC₅₀ of 1421.92 μg/mL. Yamogenin can be studied in research on gastric cancer .

HY-N17332

Betavulgaroside III	Others	Inflammation/Immunology
Betavulgaroside III is a triterpene seco-glycoside plant saponin. Betavulgaroside III exhibits anti-inflammatory activity .

HY-N19939

Saponarioside D	Others	Others
Saponarioside D is a triterpenoid saponin found in whole plants and roots of Saponaria officinalis L. .

HY-E71181

11-oxo-β-Amyrin 30-oxidase	Biochemical Assay Reagents	Others
11-oxo-β-Amyrin 30-oxidase (EC 1.14.13.173) is involved in the biosynthesis of the triterpenoid saponin glycyrrhizin in the plant Glycyrrhiza uralensis (licorice).

HY-N18692

Cactus flower extract	Others	Others
Cactus Extract is obtained from the rhizome of the plant cactus, and saponin compounds are one of the main effective ingredients in the cactus. It has a certain skin care effect, and can be used as cosmetics material.

HY-N18744

Eclipta alba extract	Others	Inflammation/Immunology
Eclipta alba extract is a versatile plant extract derived from the whole plant of Wedelia candel. It is rich in various bioactive compounds, such as eclipta lactone, wedelia saponins, ursolic acid, oleanolic acid, luteolin, and apigenin. Eclipta alba extract is a potent hepatoprotective agent, helping to improve liver function and protect the liver from damage.

HY-N19048

Semen ziziphi spinosae extract	Others	Others
Semen Ziziphi Spinosae Extract is derived from the dried seeds of Ziziphus jujuba Mill.var.spinosa, a plant of the Rhamnaceae family. The active ingredients include flavonoid glycosides, triterpenes, saponins and organic acids, etc.

HY-N18674

Fenugreek extract	Others	Metabolic Disease Inflammation/Immunology
Fenugreek extract is a natural plant extract derived from fenugreek seeds. It is rich in bioactive components such as saponins, flavonoids, alkaloids, and mucilage, which help improve blood sugar control, reduce inflammation, and promote digestive health.

HY-N19886

Pastuchoside E	Drug Derivative	Others
Pastuchoside E is a triterpenoid saponin found in the leaves of Hedera pastuchowii. Terpenes, also known as isoprene compounds, are the most numerous and structurally diverse natural products found in many plants. Terpenes can be used to treat cancer, malaria, inflammation, and various infectious diseases .

HY-N18676

Dolichos biflorus extract	Others	Metabolic Disease
Dolichos Biflorus Extract, derived from the seeds of the Dolichos biflorus plant (commonly known as horse gram), is a nutrient-dense herb widely used in Ayurvedic and traditional medicine for its numerous health benefits. Dolichos biflorus extract contains alkaloids, saponins, flavonoids, carbohydrates, proteins, and tannins. It is known for its digestive support, as it promotes healthy digestion, alleviates bloating, and helps with constipation, along with mild diuretic effects that aid detoxification by eliminating excess fluids and waste products from the body.

Saponins 5 Publications Verification saponin	Triterpenes Structural Classification Classification of Application Fields Terpenoids Camellia sinensis (L.) O. Ktze. Plants Inflammation/Immunology Disease Research Fields Source Classification Theaceae	Environmental Pollutants Bacterial Fungal
Saponins (Saponin) is a class of chemical compound of glycosides found in particular abundance in various plant species. In plants, Saponins may serve as anti-feedants, and to protect the plant against microbes and fungi .

Dioscin Maximum Cited Publications 11 Publications Verification Collettiside III; CCRIS 4123	other families Classification of Application Fields Plants Disease Research Fields Steroids Source Classification Cancer	Autophagy Apoptosis
Dioscin (CCRIS 4123; Collettiside III) is a natural plant-derived steroidal saponin that has good anti-cancer activity against a variety of cancer cells. Dioscin causes DNA damage and induces apoptosis in HeLa and SiHa cells. Dioscin regulates ROS-mediated DNA damage and mitochondrial signaling pathways, exerting anticancer activity .

Gracillin 2 Publications Verification	other families Classification of Application Fields Plants Disease Research Fields Steroids Source Classification Cancer	Apoptosis Autophagy
Gracillin is a steroidal saponin that can be extracted from the roots of the plant and has anti-tumor properties. Gracillin can induce cancer cell apoptosis and autophagy .

Yamogenin Neodiosgenin	other families Classification of Application Fields Metabolic Disease Plants Disease Research Fields Steroids Source Classification	LXR Reactive Oxygen Species (ROS) Apoptosis Fatty Acid Synthase (FASN)
Yamogenin (Neodiosgenin) is a diastereomer of diosgenin. Yamogenin antagonizes the activation of the liver X receptor (LXR) in luciferase ligand assay. Yamogenin inhibits triacylglyceride (TG) accumulation through the suppression of gene expression of fatty acid synthesis in HepG2 hepatocytes. Yamogenin is a steroidal saponin that can be obtained from plant species with in vitro cytotoxicity, antioxidant, and antimicrobial properties. Yamogenin induces cell death via the extrinsic and intrinsic way of apoptosis. Yamogenin inhibits protein denaturation with an IC₅₀ of 1421.92 μg/mL. Yamogenin can be studied in research on gastric cancer .

Licorice-saponin H2 (18β,20α)-Glycyrrhizic acid	Triterpenes Classification of Application Fields Leguminosae Terpenoids Metabolic Disease Plants Glycyrrhiza uralensis Fisch. Disease Research Fields Source Classification	Others
Liquorice-saponin H2 ((18β,20α)-Glycyrrhizic acid) is a type of triterpenoid oligosaccharide glycoside found in the Glycyrrhiza genus. Liquorice-saponin H2 accumulates more in the roots of licorice plants under salt stress conditions, suggesting that it may play a role in plant stress resistance .

Methyl gypsogenin-3-O-glucuronide Gypsogenin-3-O-(6-O-methyl)-glucoside	Triterpenes other families Classification of Application Fields Terpenoids Plants Inflammation/Immunology Disease Research Fields Source Classification	Others
Methyl gypsogenin-3-O-glucuronide (Gypsogenin-3-O-(6-O-methyl)-glucoside) is a ubiquitous saponin precursor in plants of the genus Gypsophila .

Zingibroside R1 1 Publications Verification	Infection Structural Classification Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Classification of Application Fields Panax japonicas C. A. Mey. Metabolic Disease Plants Disease Research Fields Saccharides Araliaceae Source Classification	HIV PIN1 Fungal GLUT Reactive Oxygen Species (ROS)
Zingibroside R1 is an orally active triterpene saponin with multiple biological activities including antioxidant, anti-inflammatory, antiviral, and metabolic regulatory properties. Zingibroside R1 reduces the expression of PIN family members, inhibits the expression of PLT1/PLT2, WOX5, SHR, and SCR, disrupts auxin transport and distribution, triggers plant ROS responses, and inhibits root growth. Zingibroside R1 extends the lifespan of Caenorhabditis elegans, enhances its heat stress resistance, and improves its motor ability. Hydrogel derivatives of Zingibroside R1 inhibit the proliferation of Candida albicans by binding to its β-1,3-glucan and exhibit antifungal activity. Zingibroside R1 inhibits GLUT1-mediated uptake and alleviates liver injury. Zingibroside R1 can be used in research related to neurodegenerative diseases, vulvovaginal candidiasis, acute liver injury, Ehrlich ascites tumor and HIV-1 infection .

Dioscin (Standard) Collettiside III (Standard); CCRIS 4123 (Standard)	Structural Classification other families Plants Steroids Source Classification	Reference Standards Autophagy Apoptosis
Dioscin (Standard) is the analytical standard of Dioscin. This product is intended for research and analytical applications. Dioscin (CCRIS 4123; Collettiside III) is a natural plant-derived steroidal saponin that has good anti-cancer activity against a variety of cancer cells. Dioscin causes DNA damage and induces apoptosis in HeLa and SiHa cells. Dioscin regulates ROS-mediated DNA damage and mitochondrial signaling pathways, exerting anticancer activity .

Esculentoside H 2 Publications Verification	Triterpenes Classification of Application Fields Terpenoids Phytolacca acinosa Roxb. Plants Disease Research Fields Phytolaccaceae Source Classification Cancer	NF-κB JNK
Esculentoside H (EsH) is a saponin isolated from the root extract of perennial plant Phytolacca esculenta . Esculentoside H (EH) has anti-tumor activity, the mechanism is related to the capacity for TNFrelease . Esculentoside H (EsH) suppresses colon cancer cell migration through blockage of the JNK1/2 and NF-κB signaling-mediated matrix metalloproteinases-9 (MMP-9) expression .

Kizuta saponin K11	Triterpenes other families Classification of Application Fields Terpenoids Other Diseases Plants Disease Research Fields Source Classification	Others
Kizuta saponin K11 is a saponin found in the leaves of Kalopanax pictum var. maximowiczii, a Korean medicinal plant .

Licorice-saponin H2 ammonium (18β,20α)-Glycyrrhizic acid ammonium	Triterpenes Leguminosae Terpenoids Plants Glycyrrhiza uralensis Fisch. Source Classification	Others
Liquorice-saponin H2 ((18β,20α)-Glycyrrhizic acid) ammonium is a type of triterpenoid oligosaccharide glycoside found in the Glycyrrhiza genus. Liquorice-saponin H2 ammonium accumulates more in the roots of licorice plants under salt stress conditions, suggesting that it may play a role in plant stress resistance .

Ilexoside O	Aquifoliaceae Triterpenes Classification of Application Fields Terpenoids Plants Disease Research Fields Inflammation/Immunology Tabernaemontana elegans Stapf Source Classification	Xanthine Oxidase
Ilexoside O is a triterpene saponin isolated from the roots of Ilex pubescens. Ilexoside O exhibits weak xanthine oxidase (XOD) inhibitory activity (IC₅₀=53.05 μM) .

Gracillin (Standard)	Structural Classification other families Plants Steroids Source Classification	Reference Standards Apoptosis Autophagy
Gracillin (Standard) is the analytical standard of Gracillin. This product is intended for research and analytical applications. Gracillin is a steroidal saponin that can be extracted from the roots of the plant and has anti-tumor properties. Gracillin can induce cancer cell apoptosis and autophagy .

Yamogenin (Standard) Neodiosgenin (Standard)	Structural Classification other families Plants Steroids Source Classification	Reference Standards LXR Apoptosis Fatty Acid Synthase (FASN) Reactive Oxygen Species (ROS)
Yamogenin (Standard) is the analytical standard of Yamogenin. This product is intended for research and analytical applications. Yamogenin (Neodiosgenin) is a diastereomer of diosgenin. Yamogenin antagonizes the activation of the liver X receptor (LXR) in luciferase ligand assay. Yamogenin inhibits triacylglyceride (TG) accumulation through the suppression of gene expression of fatty acid synthesis in HepG2 hepatocytes. Yamogenin is a steroidal saponin that can be obtained from plant species with in vitro cytotoxicity, antioxidant, and antimicrobial properties. Yamogenin induces cell death via the extrinsic and intrinsic way of apoptosis. Yamogenin inhibits protein denaturation with an IC₅₀ of 1421.92 μg/mL. Yamogenin can be studied in research on gastric cancer .

Betavulgaroside III	Structural Classification Polysaccharides Beta vulgaris Linn. Plants Saccharides Chenopodiaceae Source Classification	Others
Betavulgaroside III is a triterpene seco-glycoside plant saponin. Betavulgaroside III exhibits anti-inflammatory activity .

Saponarioside D	Triterpenes Structural Classification Saponaria officinalis L. Terpenoids Plants Caryophyllaceae Source Classification	Others
Saponarioside D is a triterpenoid saponin found in whole plants and roots of Saponaria officinalis L. .

Cactus flower extract	Structural Classification Extract	Others
Cactus Extract is obtained from the rhizome of the plant cactus, and saponin compounds are one of the main effective ingredients in the cactus. It has a certain skin care effect, and can be used as cosmetics material.

Eclipta alba extract	Structural Classification Extract	Others
Eclipta alba extract is a versatile plant extract derived from the whole plant of Wedelia candel. It is rich in various bioactive compounds, such as eclipta lactone, wedelia saponins, ursolic acid, oleanolic acid, luteolin, and apigenin. Eclipta alba extract is a potent hepatoprotective agent, helping to improve liver function and protect the liver from damage.

Semen ziziphi spinosae extract	Structural Classification Extract	Others
Semen Ziziphi Spinosae Extract is derived from the dried seeds of Ziziphus jujuba Mill.var.spinosa, a plant of the Rhamnaceae family. The active ingredients include flavonoid glycosides, triterpenes, saponins and organic acids, etc.

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plant saponin

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