Licorice-saponin H2
Based on 1 Customer Validation
Licorice-saponin H2 ((18β,20α)-Glycyrrhizic acid; 18β-GA; 18β-Isoglycyrrhizinic acid) is a triterpenoid saponin that can be found in the stolons of Glycyrrhiza lepidota, as well as in glycyrrhizin-producing species Glycyrrhiza glabra, Glycyrrhiza uralensis and Glycyrrhiza inflata.
For research use only. We do not sell to patients.
- Purity: 99.72%
- CAS No.: 118441-85-3
- Formula: C42H62O16
- Molecular Weight:822.93
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Hepatocyte | IC50 |
16.9 μM
Compound: 197
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Hepatotoxicity in D-GaIN induced in Wistar rat model hepatocyte assessed as reduction in PLA2 level
Hepatotoxicity in D-GaIN induced in Wistar rat model hepatocyte assessed as reduction in PLA2 level
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[PMID: 29353722] |
In Vitro
Licorice-saponin H2 is a major saponin constituent of Glycyrrhiza lepidota stolons, with contents ranging from 0.45% to 3.21% of dry weight[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 118441-85-3
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Appearance Solid
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Molecular Weight 822.93
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Formula C42H62O16
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Color White to off-white
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SMILES
C[C@]12[C@@](C(C=C3[C@]2(CC[C@]4(C)[C@@]3([H])C[C@@](C(O)=O)(C)CC4)C)=O)([H])[C@@]5([C@@](C(C)([C@@H](O[C@@]6([H])[C@@H]([C@H]([C@H](O)[C@@H](C(O)=O)O6)O)O[C@]7([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]7O)C(O)=O)CC5)C)([H])CC1)C
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Synonyms
(18β,20α)-Glycyrrhizic acid; 18β-GA; 18β-Isoglycyrrhizinic acid
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (121.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (289 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2152 mL | 6.0759 mL | 12.1517 mL | 30.3793 mL |
| 5 mM | 0.2430 mL | 1.2152 mL | 2.4303 mL | 6.0759 mL | |
| 10 mM | 0.1215 mL | 0.6076 mL | 1.2152 mL | 3.0379 mL | |
| 15 mM | 0.0810 mL | 0.4051 mL | 0.8101 mL | 2.0253 mL | |
| 20 mM | 0.0608 mL | 0.3038 mL | 0.6076 mL | 1.5190 mL | |
| 25 mM | 0.0486 mL | 0.2430 mL | 0.4861 mL | 1.2152 mL | |
| 30 mM | 0.0405 mL | 0.2025 mL | 0.4051 mL | 1.0126 mL | |
| 40 mM | 0.0304 mL | 0.1519 mL | 0.3038 mL | 0.7595 mL | |
| 50 mM | 0.0243 mL | 0.1215 mL | 0.2430 mL | 0.6076 mL | |
| 60 mM | 0.0203 mL | 0.1013 mL | 0.2025 mL | 0.5063 mL | |
| 80 mM | 0.0152 mL | 0.0759 mL | 0.1519 mL | 0.3797 mL | |
| 100 mM | 0.0122 mL | 0.0608 mL | 0.1215 mL | 0.3038 mL |
Licorice-saponin H2 Related Classifications
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