worm

By Targets:	Antibiotic (5) Apoptosis (2) Atg8/LC3 (1) Autophagy (3) Bacterial (2) Biochemical Assay Reagents (1) Cholinesterase (ChE) (1) Drug Metabolite (1) Endogenous Metabolite (1) Fungal (1) HDAC (1) Histone Demethylase (1) Isotope-Labeled Compounds (1) MDM-2/p53 (1) Microtubule/Tubulin (1) Mitochondrial Metabolism (1) nAChR (4) Parasite (15) Reactive Oxygen Species (1) STAT (1)
By Research Areas:	Cancer (4) Infection (16) Inflammation/Immunology (1) Neurological Disease (2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0294

Flubendazole Maximum Cited Publications 6 Publications Verification	Parasite Microtubule/Tubulin STAT MDM-2/p53 Apoptosis Autophagy	Infection Cancer
Flubendazole is an anthelmintic drug based on altering microtubule structure, inhibition of tubulin polymerization and disruption of microtubule function. Flubendazole induces apoptosis in human colorectal cancer (CRC) by blocking the STAT3 signaling axis and activation of autophagy. Flubendazole induces P53 expression and reduced Cyclin B1 and p-cdc2 expression. Flubendazole is an antitumor agent. Flubendazole can be used for worm and intestinal parasites .

HY-126057AS

(S)-Praziquantel-d11	Isotope-Labeled Compounds	Others
(S)-Praziquantel-d₁₁ is the deuterium labeled (S)-Praziquantel. (S)-Praziquantel, a toxic enantiomerof Praziquantel, is ineffective against worms[1].

HY-15648C

GSK-J5 1 Publications Verification	Histone Demethylase Parasite	Cancer
GSK-J5 is a potent inhibitor of Schistosome and worm. GSK-J5 increases schistosomula mortality and adult worm motility and mortality, as well as egg oviposition, in a dose- and time-dependent manner .

HY-W158234

N-Methylbenzo[d]oxazol-2-amine	Parasite	Infection
N-Methylbenzo[d]oxazol-2-amine (compound 1) is an anthelmintic activity and lower cytotoxicity against T. spiralis adult worm. N-Methylbenzo[d]oxazol-2-amine up-regulates the metabolism of purine, pyrimidine and down-regulates sphingolipid metabolism .

HY-N12622

AChE-IN-58	Cholinesterase (ChE)	Neurological Disease
AChE-IN-58 (Compound 3) is an acetylcholinesterase (AChE) inhibitor. AChE-IN-58 can extend the mean lifespan, delay the Aβ₁-42-induced paralysis, enhanc the locomotion, and alleviate glutamic acid (Glu)-induced neurotoxicity of CL4176 worms .

HY-B2186

Piperazine adipate

Parasite Infection

Piperazine adipate is a potent broad spectrum anthelmintic against many common worm infections in mammals.
HY-B1761

Santonin

Alpha-Santonin
Parasite Infection

Santonin is an active principle of the plant Artemisia cina, which is formely used to treat worms .

Piperazine adipate	Parasite	Infection
Piperazine adipate is a potent broad spectrum anthelmintic against many common worm infections in mammals.

Santonin Alpha-Santonin	Parasite	Infection
Santonin is an active principle of the plant Artemisia cina, which is formely used to treat worms .

HY-B0263R

Thiabendazole (Standard) Tiabendazole (Standard); 2-(4-Thiazolyl)benzimidazole (Standard)	Mitochondrial Metabolism Parasite	Infection
Thiabendazole (Standard) is the analytical standard of Thiabendazole. This product is intended for research and analytical applications. Thiabendazole inhibits worm-specific fumarate reductase and has anthelmintic properties.

HY-135410

ABZ-amine Amino albendazole	Drug Metabolite	Infection
ABZ-amine (Amino albendazole) is an impurity of Albendazole. Albendazole is a member of the benzimidazole compounds used as a agent indicated for the treatment of a variety of worm infestations .

HY-126389

Chitin, from crab carapace (powder)	Biochemical Assay Reagents Endogenous Metabolite	Others
Chitin, from crab carapace (powder) is a variety of sugars extracted from the shells of marine crustaceans. In nature, chitin widely exists in shrimp, crabs, and worms.

HY-B0223S

Albendazole-d3 SKF-62979-d₃	Parasite	Infection
Albendazole-d₃ is the deuterium labeled Albendazole, which is a member of the benzimidazole compounds used as a agent indicated for the treatment of a variety of worm infestations[1].

HY-P1763

Urechistachykinin II Uru-TK II	Bacterial	Infection
Urechistachykinin II (Uru-TK II), an invertebrate tachykinin-related peptides (TRPs) isolated from echiuroid worms, shows antimicrobial activities without a hemolytic effect .

HY-P1768

Urechistachykinin I Uru-TK I	Bacterial	Infection
Urechistachykinin I (Uru-TK I), an invertebrate tachykinin-related peptides (TRPs) isolated from echiuroid worms, shows antimicrobial activities without a hemolytic effect .

HY-121546

ALLO-1	Atg8/LC3 Autophagy	Cancer
ALLO-1, an autophagy receptor, is essential for autophagosome formation around paternal organelles and directly binds to the worm LC3 homologue LGG-1 through its LC3-interacting region (LIR) motif .

HY-124874

(rel)-Asperparaline A (rel)-Aspergillimide; (rel)-VM55598	nAChR	Neurological Disease
(rel)-Asperparaline A ((rel)-Aspergillimide), an anthelmintic metabolite, is isolated from okara that has been fermented with Aspergillus japonicas JV-23. (rel)-Asperparaline A is also a potent and selective antagonist of nAChR. (rel)-Asperparaline A exhibits paralytic activity in silk worms .

HY-12641A

Pyrantel
Pyrantel is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel can cause spasmodic muscle paralysis in parasites. Pyrantel can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis .

HY-12641

Pyrantel tartrate	Parasite nAChR Antibiotic	Infection
Pyrantel tartrate is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel tartrate can cause spasmodic muscle paralysis in parasites. Pyrantel tartrate can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis .

HY-12640

Pyrantel pamoate Pyrantel embonate	Parasite nAChR Antibiotic	Infection
Pyrantel pamoate (Pyrantel embonate) is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel pamoate can cause spasmodic muscle paralysis in parasites. Pyrantel pamoate can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis .

HY-151133

Antiparasitic agent-9	Parasite	Infection
Antiparasitic agent-9 (compound 47) is an orally active and potent antiparasitic agent. Antiparasitic agent-9 shows antiparasitic activity against the human parasite .

HY-B0778

Milbemycin oxime	Antibiotic Parasite	Infection
Milbemycin oxime is an orally active macrolide with broad-spectrum antiparasitic activity. Milbemycin oxime is a mixture of oximes consisting of oxime derivatives corresponding to milbemycin A4 and A3. Milbemycin oxime binds to glutamate-gated chloride channels and has inhibitory potency against intestinal nematodes and lung/heart worms .

HY-15311

Avermectin B1 4 Publications Verification Abamectin; Avermectin B1a-Avermectin B1b mixt.	Parasite Autophagy Apoptosis Reactive Oxygen Species Antibiotic	Infection Inflammation/Immunology
Avermectin B1 (Abamectin) is a mixture of two similar segments of avermectin. Avermectin B1 is an orally anti-infection agent, which can be used in the research of parasitic worms, insect pests, agriculture and animal husbandry. Avermectin B1 can also induce the production of ROS and induces cytotoxicity, apoptosis and autophagy .

HY-12640R

Pyrantel pamoate (Standard) Pyrantel embonate (Standard)	Parasite nAChR Antibiotic	Infection
Pyrantel (pamoate) (Standard) is the analytical standard of Pyrantel (pamoate). This product is intended for research and analytical applications. Pyrantel pamoate (Pyrantel embonate) is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel pamoate can cause spasmodic muscle paralysis in parasites. Pyrantel pamoate can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis .

HY-144098

HDAC8-IN-2	Parasite HDAC	Others
HDAC8-IN-2 (compound 5o) is a potent HDAC8 inhibitor, with IC₅₀ values of 0.27 and 0.32 μM for smHDAC8 (Schistosoma mansoni histone deacetylase 8) and hHDAC8, respectively. HDAC8-IN-2 shows significant killing of the schistosome larvae. HDAC8-IN-2 markedly impairs egg laying of adult worm pairs .

HY-13582

Carbendazim 4 Publications Verification	Fungal Parasite	Infection Cancer
Carbendazim is a potent and orally active broad-spectrum benzimidazole fungicide and can be acts as a pesticide for fungal diseases research, such as Seproria, Fusarium and Sclerotina . Carbendazim is a benzimidazole (HY-Y1825) derivative with antitumor activity and used for cancer research, especially advanced solid tumors and lymphoma .

Cat. No.	Product Name

HY-L007

Immunology/Inflammation Compound Library	5006 compounds
The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease. To function properly, an immune system must detect a wide variety of agents, known as pathogens, from viruses to parasitic worms, and distinguish them from the organism's own healthy tissue. Inflammation is also the body's attempt at self-protection to remove harmful stimuli and begin the healing process. It’s part of the body's immune response. The immune system recognizes damaged cells, irritants, and pathogens, and inflammation begins the healing process. Inflammatory abnormalities are a large group of disorders that underlie a vast variety of human diseases. The immune system is often involved with inflammatory disorders, demonstrated in both allergic reactions and some myopathies, with many immune system disorders resulting in abnormal inflammation. MCE designs a unique collection of 5006 compounds that are useful tool for Immunology/Inflammation research or autoimmune inflammatory diseases drug discovery.

Immunology/Inflammation Compound Library

5006 compounds

The immune system is a host defense system comprising many biological structures and processes within an organism that protects against disease. To function properly, an immune system must detect a wide variety of agents, known as pathogens, from viruses to parasitic worms, and distinguish them from the organism's own healthy tissue. Inflammation is also the body's attempt at self-protection to remove harmful stimuli and begin the healing process. It’s part of the body's immune response. The immune system recognizes damaged cells, irritants, and pathogens, and inflammation begins the healing process. Inflammatory abnormalities are a large group of disorders that underlie a vast variety of human diseases. The immune system is often involved with inflammatory disorders, demonstrated in both allergic reactions and some myopathies, with many immune system disorders resulting in abnormal inflammation.

MCE designs a unique collection of 5006 compounds that are useful tool for Immunology/Inflammation research or autoimmune inflammatory diseases drug discovery.

Cat. No.	Product Name	Type

HY-126389

Chitin, from crab carapace (powder)	Biochemical Assay Reagents
Chitin, from crab carapace (powder) is a variety of sugars extracted from the shells of marine crustaceans. In nature, chitin widely exists in shrimp, crabs, and worms.

Cat. No.	Product Name	Target	Research Area

HY-P5166

Lys-Conopressin-G

Peptides Others

Lys-Conopressin-G, a vasotocin-like peptide, can be isolated from the venom of the worm-hunting snail (conus imperialis) .

Lys-Conopressin-G	Peptides	Others
Lys-Conopressin-G, a vasotocin-like peptide, can be isolated from the venom of the worm-hunting snail (conus imperialis) .

HY-P1763

Urechistachykinin II Uru-TK II	Bacterial	Infection
Urechistachykinin II (Uru-TK II), an invertebrate tachykinin-related peptides (TRPs) isolated from echiuroid worms, shows antimicrobial activities without a hemolytic effect .

HY-P1768

Urechistachykinin I Uru-TK I	Bacterial	Infection
Urechistachykinin I (Uru-TK I), an invertebrate tachykinin-related peptides (TRPs) isolated from echiuroid worms, shows antimicrobial activities without a hemolytic effect .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1761

Santonin Alpha-Santonin	Other Terpenoids Infection Structural Classification Classification of Application Fields Terpenoids Plants Compositae Disease Research Fields Astragalus membranaceus (Fisch.) Bunge	Parasite
Santonin is an active principle of the plant Artemisia cina, which is formely used to treat worms .

HY-126389

Chitin, from crab carapace (powder)	Structural Classification Natural Products Human Gut Microbiota Metabolites Polysaccharides Microorganisms Animals Source classification Endogenous metabolite Saccharides	Biochemical Assay Reagents Endogenous Metabolite
Chitin, from crab carapace (powder) is a variety of sugars extracted from the shells of marine crustaceans. In nature, chitin widely exists in shrimp, crabs, and worms.

HY-B0778

Milbemycin oxime	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Antibiotic Parasite
Milbemycin oxime is an orally active macrolide with broad-spectrum antiparasitic activity. Milbemycin oxime is a mixture of oximes consisting of oxime derivatives corresponding to milbemycin A4 and A3. Milbemycin oxime binds to glutamate-gated chloride channels and has inhibitory potency against intestinal nematodes and lung/heart worms .

HY-N12622

AChE-IN-58	Structural Classification Flavonoids Flavones Source classification Camellia sinensis (L.) O. Ktze. Plants Theaceae	Cholinesterase (ChE)
AChE-IN-58 (Compound 3) is an acetylcholinesterase (AChE) inhibitor. AChE-IN-58 can extend the mean lifespan, delay the Aβ₁-42-induced paralysis, enhanc the locomotion, and alleviate glutamic acid (Glu)-induced neurotoxicity of CL4176 worms .

HY-124874

(rel)-Asperparaline A (rel)-Aspergillimide; (rel)-VM55598	Alkaloids Microorganisms Pyrrole Alkaloids Source classification	nAChR
(rel)-Asperparaline A ((rel)-Aspergillimide), an anthelmintic metabolite, is isolated from okara that has been fermented with Aspergillus japonicas JV-23. (rel)-Asperparaline A is also a potent and selective antagonist of nAChR. (rel)-Asperparaline A exhibits paralytic activity in silk worms .

HY-15311

Avermectin B1 4 Publications Verification Abamectin; Avermectin B1a-Avermectin B1b mixt.	Structural Classification Classification of Application Fields Source classification Anti-parasitic Antibacterial Disease Research Biological Pesticide Research Agricultural Research Infection Microorganisms Macrolide Antibiotics Antibiotics Animal Husbandry Inflammation/Immunology Disease Research Fields	Parasite Autophagy Apoptosis Reactive Oxygen Species Antibiotic
Avermectin B1 (Abamectin) is a mixture of two similar segments of avermectin. Avermectin B1 is an orally anti-infection agent, which can be used in the research of parasitic worms, insect pests, agriculture and animal husbandry. Avermectin B1 can also induce the production of ROS and induces cytotoxicity, apoptosis and autophagy .

Cat. No.	Product Name	Chemical Structure

HY-126057AS

(S)-Praziquantel-d11

(S)-Praziquantel-d₁₁ is the deuterium labeled (S)-Praziquantel. (S)-Praziquantel, a toxic enantiomerof Praziquantel, is ineffective against worms[1].

(S)-Praziquantel-d11
(S)-Praziquantel-d₁₁ is the deuterium labeled (S)-Praziquantel. (S)-Praziquantel, a toxic enantiomerof Praziquantel, is ineffective against worms[1].

HY-B0223S

Albendazole-d3
Albendazole-d₃ is the deuterium labeled Albendazole, which is a member of the benzimidazole compounds used as a agent indicated for the treatment of a variety of worm infestations[1].

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Screening Libraries

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worm

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