1. Anti-infection
  2. Parasite
    Antibiotic
  3. Milbemycin oxime

Milbemycin oxime 

Cat. No.: HY-B0778 Purity: 99.82%
Handling Instructions

Milbemycin oxime is a macrocyclic lactone and has broad-spectrum anti-parasitic activity. Milbemycin oxime is composed of milbemycins A4 and A3. Milbemycin oxime binds glutamate-gated chloride channels. Milbemycin oxime is against intestinal nematodes, pulmonary and cardiac helminths.

For research use only. We do not sell to patients.

Milbemycin oxime Chemical Structure

Milbemycin oxime Chemical Structure

CAS No. : 129496-10-2

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply Now  
Solution
10 mM * 1 mL in DMSO USD 72 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 72 In-stock
Estimated Time of Arrival: December 31
Solid
10 mg USD 60 In-stock
Estimated Time of Arrival: December 31
50 mg USD 84 In-stock
Estimated Time of Arrival: December 31
100 mg USD 120 In-stock
Estimated Time of Arrival: December 31
200 mg USD 180 In-stock
Estimated Time of Arrival: December 31
500 mg   Get quote  
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Description

Milbemycin oxime is a macrocyclic lactone and has broad-spectrum anti-parasitic activity. Milbemycin oxime is composed of milbemycins A4 and A3. Milbemycin oxime binds glutamate-gated chloride channels. Milbemycin oxime is against intestinal nematodes, pulmonary and cardiac helminths[1][2][3].

Molecular Weight

1097.38

Formula

C₆₃H₈₈N₂O₁₄

CAS No.
SMILES
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Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (91.13 mM)

H2O : 1 mg/mL (0.91 mM; ultrasonic and warming and heat to 80°C)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9113 mL 4.5563 mL 9.1126 mL
5 mM 0.1823 mL 0.9113 mL 1.8225 mL
10 mM 0.0911 mL 0.4556 mL 0.9113 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (2.28 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: 2.5 mg/mL (2.28 mM); Suspended solution; Need ultrasonic

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (2.28 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.82%

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Keywords:

Milbemycin oximeParasiteAntibioticInhibitorinhibitorinhibit

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Product Name:
Milbemycin oxime
Cat. No.:
HY-B0778
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