2. Anti-infection
  3. Fungal Parasite
  4. Carbendazim

Carbendazim 

Cat. No.: HY-13582 Purity: 99.85%
COA Handling Instructions

Carbendazim is a potent and orally active broad-spectrum benzimidazole fungicide and can be acts as a pesticide for fungal diseases research, such as Seproria, Fusarium and Sclerotina. Carbendazim is a benzimidazole (HY-Y1825) derivative with antitumor activity and used for cancer research, especially advanced solid tumors and lymphoma.

For research use only. We do not sell to patients.

Carbendazim Chemical Structure

Carbendazim Chemical Structure

CAS No. : 10605-21-7

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Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 33 In-stock
Solution
10 mM * 1 mL in DMSO USD 33 In-stock
Solid
100 mg USD 30 In-stock
500 mg USD 75 In-stock
1 g USD 108 In-stock
5 g USD 324 In-stock
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Customer Review

Based on 4 publication(s) in Google Scholar

Other Forms of Carbendazim:

Carbendazim Related Antibodies

Top Publications Citing Use of Products

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Carbendazim is a potent and orally active broad-spectrum benzimidazole fungicide and can be acts as a pesticide for fungal diseases research, such as Seproria, Fusarium and Sclerotina[1][3]. Carbendazim is a benzimidazole (HY-Y1825) derivative with antitumor activity and used for cancer research, especially advanced solid tumors and lymphoma[3].

In Vitro

Carbendazim (4-60 μM; 24 hours) has no effects on viability of HeLa cells in a CCK-8 assay[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Carbendazim Related Antibodies
In Vivo

Carbendazim (oral gavage; 100 and 500 mg/kg; once daily in diet; 28 days) induces hepatic lipid metabolism disorder, it results in a significant increase of hepatic lipid accumulation and triglyceride (TG) levels in mice[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 6-week-old male ICR mice[2]
Dosage: 100 and 500 mg/kg
Administration: Oral gavage; 100 and 500 mg/kg; once daily in diet; 28 days
Result: Increased the relative mRNA levels of some key genes related to lipogenesis and TG synthesis.
Up-regulated mRNA levels of IL-1b and IL-6 in the liver in mice.
Increased the serum concentrations of 2 proinflammatory cytokines IL-1b and IL-6 at 500 mg/kg. However, in the fat tissues, onlyIL-1b in the CBZ-500-treated group increased significantly as compared with the control group.
Clinical Trial
Molecular Weight

191.19

Appearance

Solid

Formula

C9H9N3O2
CAS No.
SMILES

O=C(OC)NC1=NC2=CC=CC=C2N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 6.8 mg/mL (35.57 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.2304 mL 26.1520 mL 52.3040 mL
5 mM 1.0461 mL 5.2304 mL 10.4608 mL
10 mM 0.5230 mL 2.6152 mL 5.2304 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 0.5 mg/mL (2.62 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% Corn Oil

    Solubility: ≥ 0.5 mg/mL (2.62 mM); Clear solution

*All of the co-solvents are available by MedChemExpress (MCE).
Purity & Documentation
References
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Carbendazim Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Carbendazim10605-21-7FungalParasitebenzimidazole fungicidecasting worm control agenthepatic lipid metabolism disordergut microbiotainflammationSeproriaFusariumSclerotinaadvanced solid tumorslymphomaInhibitorinhibitorinhibit

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