Search Result
Results for "
2-4-2-hydroxyethyl-piperazin-1-yldithiazepin-d8
" in MedChemExpress (MCE) Product Catalog:
10
Biochemical Assay Reagents
9
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-20128
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Biochemical Assay Reagents
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Others
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Piperazin-2-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
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- HY-W020111
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Sirtuin
Parasite
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Infection
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7-Chloro-4-(piperazin-1-yl)quinolone is an important scaffold in medicinal chemistry. 7-Chloro-4-(piperazin-1-yl)quinolone is a potent sirtuin inhibitor and also inhibits the serotonin uptake (IC50 of 50 μM). 7-Chloro-4-(piperazin-1-yl)quinolone exhibits antimalarial activity on D10 and K1 strains of P. falciparum with IC50s of 1.18 μM and 0.97 μM, respectively .
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- HY-W052508S
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Isotope-Labeled Compounds
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Others
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11-(Piperazin-1-yl)dibenzo[b,f][1,4]thiazepine-d8 is the deuterium labeled 11-(Piperazin-1-yl)dibenzo[b,f][1,4]thiazepine[1].
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- HY-20128S
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- HY-W009512S
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Isotope-Labeled Compounds
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Others
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N-(2,6-Dimethylphenyl)-2-(piperazin-1-yl)acetamide-d8 is the deuterium labeled N-(2,6-Dimethylphenyl)-2-(piperazin-1-yl)acetamide[1].
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- HY-W012723
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Biochemical Assay Reagents
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Others
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2-Hydroxyethyl methacrylate (HEMA) is a monomer used in the synthesis of various polymers, and the polymer PHEMA of 2-Hydroxyethyl methacrylate is widely used in the synthesis of dental composite materials .
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- HY-140125
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ADC Linker
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Cancer
|
2-Hydroxyethyl disulfide mono-tosylate is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-132313S
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- HY-118213
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Fluorescent Dye
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Others
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N-(2-Hydroxyethyl)-1,8-naphthalimide is a fluorescent probe for detecting nucleic acids and their precursors. The fluorescence of N-(2-Hydroxyethyl)-1,8-naphthalimide will be quenched by these molecules.
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- HY-W042853
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- HY-W585980S
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Bis(2-butoxyethyl) 2-hydroxyethyl phosphate-d4
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Isotope-Labeled Compounds
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Others
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Bis(2-butoxyethyl) 2-hydroxyethyl phosphate-d4 (Bis(2-butoxyethyl) 2-hydroxyethyl phosphate-d4) is a deuterium labeled compound.
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- HY-B2221B
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hydroxyethyl pectin glycosidase
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Biochemical Assay Reagents
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Others
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Hydroxyethyl cellulose is a non-ionic, modified cellulose polymer used as a thickening agent for aqueous cosmetic and personal care formulations.
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- HY-140126
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ADC Linker
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Cancer
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Bis-Tos-(2-hydroxyethyl disulfide) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
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- HY-112531
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Others
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Others
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Poly(2-hydroxyethyl methacrylate) (MW 20000) is one of the most important hydrogels in the biomaterials world. Poly(2-hydroxyethyl methacrylate) is the basic component of contact lenses, and is also used in implantation of soft tissues, synthetic transplant for gristle and bone, regeneration of neurotic tissue, transmission of agent and etc .
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- HY-112531A
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Others
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Others
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Poly(2-hydroxyethyl methacrylate) (MW 1000000) is one of the most important hydrogels in the biomaterials world. Poly(2-hydroxyethyl methacrylate) is the basic component of contact lenses, and is also used in implantation of soft tissues, synthetic transplant for gristle and bone, regeneration of neurotic tissue, transmission of agent and etc .
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- HY-W145519
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Biochemical Assay Reagents
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Others
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Hydroxyethyl starch is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-156513
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ADC Cytotoxin
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Cancer
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7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin) is a Camptothecin (HY-16560) analogue. 7-Hydroxyethyl carbamate-(10Me-11F-Camptothecin) is a ADC cytotoxin that can be used for synthesis of ADCs, and for cancer research .
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- HY-143790S
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- HY-W127642
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Bis(2-hydroxyethyl)dimethylaminium chloride
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Biochemical Assay Reagents
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Others
|
Bis(2-hydroxyethyl)dimethylammonium Chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-W127783
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- HY-N10365
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Others
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Neurological Disease
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6-(1-Hydroxyethyl)-5,6-dihydrochelerythrine, a alkaloid, significantly perturbates the features of cellular organelles including early endosomes, mitochondria and autophagosomes (Parkinson’s Disease patient-derived olfactory cells) .
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- HY-N10358
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NF-κB
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Others
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3-(2-Hydroxyethyl) thio withaferin A is a Withaferin A derivative. Withaferin A, a steroidal lactone, inhibits NF-kB activation and targets vimentin, with potent antiinflammatory and anticancer activities. Withaferin A is an inhibitor of endothelial protein C receptor (EPCR) shedding .
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- HY-20797S
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- HY-154161
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Nucleoside Antimetabolite/Analog
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Cancer
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5-(2-Hydroxyethyl)-2’-deoxy uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-41939
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1-(2-Hydroxyethyl)piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-132805S
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Isotope-Labeled Compounds
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Others
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N-Acetyl-S-(2-hydroxyethyl)-L-cysteine-d4 (dicyclohexylamine) is the deuterium labeled N-Acetyl-S-(2-hydroxyethyl)-L-cysteine dicyclohexylamine salt[1].
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- HY-152790
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Nucleoside Antimetabolite/Analog
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Others
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5-(2-Hydroxyethyl)uridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis .
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- HY-W092298S
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- HY-154699
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Nucleoside Antimetabolite/Analog
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Cancer
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5-(2-Hydroxyethyl)cytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities .
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- HY-138094
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Drug Metabolite
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Infection
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N-(2-hydroxyethyl)-oxamic acid is formed when Metronidazole is reduced either chemically or by the action of the intestinal bacteria. Metronidazole, a nitroimidazole antibiotic, has activity against various protozoans and most Gram-negative and Gram-positive anaerobic bacteria .
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- HY-W440816
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Liposome
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Others
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Heptadecan-9-yl 8-((2-hydroxyethyl)amino)octanoate is a lipid that can be used for compound synthesis .
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- HY-154160
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Nucleoside Antimetabolite/Analog
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Cancer
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5-(2-Hydroxyethyl)-2’,3’-di-O-toluoyl-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-B1209
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7-(β-hydroxyethyl)theophylline
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Others
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Cardiovascular Disease
|
Etofylline (7-(β-Hydroxyethyl)theophylline) is a N-7-substituted derivative of Theophylline. Etofylline is a bronchodilator which can be used for the research of asthma. Etofylline is also an anticholesteremic and reduces total cholesterol level in the blood .
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- HY-W006957
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Nucleoside Antimetabolite/Analog
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Cancer
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N6-(2-Hydroxyethyl)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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-
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- HY-W127365
-
|
Biochemical Assay Reagents
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Others
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Dimethyl-DL-2,3-distearoyloxypropyl(2-hydroxyethyl)ammonium (acetate) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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- HY-147018
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Liposome
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Others
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1-Octylnonyl 8-[[8-[(1-ethylnonyl)oxy]-8-oxooctyl](2-hydroxyethyl)amino]octanoate is a PEG lipid. 1-Octylnonyl 8-[[8-[(1-ethylnonyl)oxy]-8-oxooctyl](2-hydroxyethyl)amino]octanoate can be used for researching drug delivery .
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-
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- HY-152324
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|
Nucleoside Antimetabolite/Analog
|
Cancer
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2-Chloro-N6-(2-hydroxyethyl)adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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- HY-P3124A
-
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Somatostatin Receptor
|
Cancer
|
BIM-23190 hydrochloride, a somatostatin analog, a selective SSRT2 and SSRT5 agonist, exhibits Ki values of 0.34 nM and 11.1 nM for SSTR2 and SSTR5, respectively. BIM-23190 can be used in the study for cancer and acromegaly .
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- HY-P3124
-
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Somatostatin Receptor
|
Cancer
|
BIM-23190, a somatostatin analog, a selective SSTR2 and SSTR5 agonist, exhibits Ki values of 0.34 nM and 11.1 nM for SSTR2 and SSTR5, respectively. BIM-23190 can be used in the study for cancer and acromegaly .
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- HY-148363
-
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Liposome
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Inflammation/Immunology
|
Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate can be used in lipid nanoparticles (LNP) delivery systems for mRNA vaccine delivery .
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-
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- HY-D1551
-
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Fluorescent Dye
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Others
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10-(4-(Bis(2-hydroxyethyl)amino)phenyl)-5,5-difluoro-1,3,7,9-tetramethyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide, a BODIPY derivative, is a fluorescent indicator for detecting Pb 2+ (Ex=504 nM, Em=510 nM) .
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-
-
- HY-W012728
-
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Biochemical Assay Reagents
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Others
|
2-(Piperidin-1-yl)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
-
- HY-W127668
-
|
Biochemical Assay Reagents
|
Others
|
(2-hydroxyethyl)triethylammonium iodide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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-
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- HY-148100
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NOX-E36
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Others
|
Inflammation/Immunology
Cancer
|
Emapticap pegol is a inhibitor of pro-inflammatory chemokine C-C motif-ligand 2 (CCL2). Emapticap pegol is a 40-nucleotide oligonucleotide aptamer, displays different Spiegelmers (L-RNA aptamer) isform in human (NOX-E36) and mouse (mNOX-E36) .
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- HY-125734
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Liposome
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Others
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DMHAPC-Chol, a cationic lipid, contains a biodegradable carbamoyl linker and a hydroxyethyl group in the polar amino head moiety. DMHAPC-Chol can be used in both transfection experiments concerning plasmids or siRNA .
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- HY-A0144
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Etilefrine (3-[2-(ethylamino)-1-hydroxyethyl]phenol) is an α adrenergic agonist . Etilefrine also is an AMPK activator . Etilefrine can be used for the research of postural hypotension .
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- HY-117006
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1-{4-[2-(5-Methylfuran-2-yl)quinoline-4-carbonyl]piperazin-1-yl}ethan-1-one
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Sirtuin
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Cardiovascular Disease
|
E1231 is an orally active activator of Sirtuin 1 (SIRT1) (EC50=0.83 μM), to modulate cholesterol and lipid metabolism. E1231 interactes with SIRT1 (KD=9.61 μM) and deacetylated liver X receptor-alpha (LXRα), and increases ATP-binding cassette transporter A1 (ABCA1) expression. E1231 also reduces atherosclerotic plaque development in ApoE -/- mice model. E1231 can be used for research in cholesterol and lipid disorder-related diseases .
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-
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- HY-79513
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tert-Butyl [(R)-1-(methoxycarbonyl)-2-hydroxyethyl]carbamate
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Amino Acid Derivatives
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Others
|
(R)-Methyl 2-(tert-butoxycarbonylamino)-3-hydroxypropanoate is a serine derivative .
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-
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- HY-15738
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GNF-5
3 Publications Verification
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Bcr-Abl
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Cancer
|
GNF-5, the N-hydroxyethyl carboxamide analog of GNF-2, is an orally active Bcr-Abl inhibitor. GNF-5 has Bcr-Abl inhibition activity with an IC50 value of 0.22 µM. GNF-5 has good favorable pharmacokinetic properties. GNF-5 can be used for the research of kinds of cancer including chronic myelogenous leukemia (CML) and breast cancer .
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-
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- HY-P3066
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d(CH2)5Tyr(Et)VAVP
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Vasopressin Receptor
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Metabolic Disease
|
SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-118213
-
|
Fluorescent Dyes/Probes
|
N-(2-Hydroxyethyl)-1,8-naphthalimide is a fluorescent probe for detecting nucleic acids and their precursors. The fluorescence of N-(2-Hydroxyethyl)-1,8-naphthalimide will be quenched by these molecules.
|
Cat. No. |
Product Name |
Type |
-
- HY-20128
-
|
Biochemical Assay Reagents
|
Piperazin-2-one is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W145519
-
|
Biochemical Assay Reagents
|
Hydroxyethyl starch is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-153124
-
-
- HY-W127642
-
Bis(2-hydroxyethyl)dimethylaminium chloride
|
Biochemical Assay Reagents
|
Bis(2-hydroxyethyl)dimethylammonium Chloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W440816
-
|
Drug Delivery
|
Heptadecan-9-yl 8-((2-hydroxyethyl)amino)octanoate is a lipid that can be used for compound synthesis .
|
-
- HY-W127365
-
|
Biochemical Assay Reagents
|
Dimethyl-DL-2,3-distearoyloxypropyl(2-hydroxyethyl)ammonium (acetate) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-147018
-
|
Drug Delivery
|
1-Octylnonyl 8-[[8-[(1-ethylnonyl)oxy]-8-oxooctyl](2-hydroxyethyl)amino]octanoate is a PEG lipid. 1-Octylnonyl 8-[[8-[(1-ethylnonyl)oxy]-8-oxooctyl](2-hydroxyethyl)amino]octanoate can be used for researching drug delivery .
|
-
- HY-148363
-
|
Drug Delivery
|
Heptadecan-9-yl 8-((6-(decyloxy)-6-oxohexyl)(2-hydroxyethyl)amino)octanoate can be used in lipid nanoparticles (LNP) delivery systems for mRNA vaccine delivery .
|
-
- HY-W012728
-
|
Biochemical Assay Reagents
|
2-(Piperidin-1-yl)ethanol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-W127668
-
|
Biochemical Assay Reagents
|
(2-hydroxyethyl)triethylammonium iodide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-W127783
-
-
- HY-P3124A
-
|
Somatostatin Receptor
|
Cancer
|
BIM-23190 hydrochloride, a somatostatin analog, a selective SSRT2 and SSRT5 agonist, exhibits Ki values of 0.34 nM and 11.1 nM for SSTR2 and SSTR5, respectively. BIM-23190 can be used in the study for cancer and acromegaly .
|
-
- HY-P4761
-
|
Peptides
|
Others
|
N-2-Hydroxyethyl-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
-
- HY-P3124
-
|
Somatostatin Receptor
|
Cancer
|
BIM-23190, a somatostatin analog, a selective SSTR2 and SSTR5 agonist, exhibits Ki values of 0.34 nM and 11.1 nM for SSTR2 and SSTR5, respectively. BIM-23190 can be used in the study for cancer and acromegaly .
|
-
- HY-P4756
-
|
Peptides
|
Others
|
N-(2-Carbamoyl-ethyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
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- HY-P4755
-
|
Peptides
|
Others
|
N-((RS)-2-Hydroxy-propyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
|
-
- HY-158104
-
|
Peptides
|
Others
|
LPPM-8 is a ligand of Med25 and an inhibitor of Med25 protein-protein interactions (PPIs). LPPM-8 engages Med25 through interaction with the H2 face of its Activator Interaction Domain and stabilizes full-length protein in the cellular proteome. LPPM-8 is an orthosteric inhibitor of H2-binding transcriptional activators (such as ATF6a). LPPM-8 can be used for studying Med25 and Mediator complex biology .
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- HY-79513
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tert-Butyl [(R)-1-(methoxycarbonyl)-2-hydroxyethyl]carbamate
|
Amino Acid Derivatives
|
Others
|
(R)-Methyl 2-(tert-butoxycarbonylamino)-3-hydroxypropanoate is a serine derivative .
|
-
- HY-P3066
-
d(CH2)5Tyr(Et)VAVP
|
Vasopressin Receptor
|
Metabolic Disease
|
SKF 100398 (d(CH2)5Tyr(Et)VAVP), an arginine vasopressin (AVP) analogue, is a specific antagonist of the antidiuretic effect of exogenous and endogenous AVP .
|
-
- HY-125357
-
|
Peptides
|
Metabolic Disease
|
Ternatin (compound 2) is a cyclic heptapeptides that can be isolated from mushroom Coliorus versicolor. Ternatin inhibits fat-accumulation with an IC50 of 0.027 μM in 3T3-L1 adipocytes .
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
-
- HY-W052508S
-
|
11-(Piperazin-1-yl)dibenzo[b,f][1,4]thiazepine-d8 is the deuterium labeled 11-(Piperazin-1-yl)dibenzo[b,f][1,4]thiazepine[1].
|
-
-
- HY-20128S
-
|
Piperazin-2-one-d6 is the deuterium labeled Piperazin-2-one[1].
|
-
-
- HY-W009512S
-
|
N-(2,6-Dimethylphenyl)-2-(piperazin-1-yl)acetamide-d8 is the deuterium labeled N-(2,6-Dimethylphenyl)-2-(piperazin-1-yl)acetamide[1].
|
-
-
- HY-132313S
-
|
2-(1-Hydroxyethyl) promazine-d4 Sulfoxide is the deuterium labeled 2-(1-Hydroxyethyl) promazine-d4 Sulfox[1].
|
-
-
- HY-W585980S
-
|
Bis(2-butoxyethyl) 2-hydroxyethyl phosphate-d4 (Bis(2-butoxyethyl) 2-hydroxyethyl phosphate-d4) is a deuterium labeled compound.
|
-
-
- HY-143790S
-
|
N-2-(Hydroxyethyl)-L-valine-d4 is the deuterium labeled N-2-(Hydroxyethyl)-L-valine[1].
|
-
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- HY-20797S
-
|
1-BOC-4-(2-Hydroxyethyl)piperazine-d4 is the deuterium labeled 1-BOC-4-(2-Hydroxyethyl)piperazine[1].
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-
-
- HY-132805S
-
|
N-Acetyl-S-(2-hydroxyethyl)-L-cysteine-d4 (dicyclohexylamine) is the deuterium labeled N-Acetyl-S-(2-hydroxyethyl)-L-cysteine dicyclohexylamine salt[1].
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-
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- HY-W092298S
-
|
Methyl 4-(2-hydroxyethyl)benzoate- 13C6,d2 is 13C and deuterated labeled Methyl 4-(2-hydroxyethyl)benzoate (HY-W092298).
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