PFI-7-O-C4-piperazin
PFI-7-O-C4-piperazin is a E3 ligase ligand-linker conjugate that can be used for synthesis of PROTACs, such as NEP162 (HY-174996). The E3 ligase ligand (PFI-7) of NEP162 is a highly selective antagonist of GID4 (KD = 0.22 μM). NEP162 is a BRD4 PROTAC degrader with anti-tumor activity[1].
For research use only. We do not sell to patients.
- Formula: C31H41N7O2
- Molecular Weight:543.70
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All E3 Ligase Ligand-Linker Conjugates Isoforms
More
Biological Activity
Chemical Information
-
Molecular Weight 543.70
-
Formula C31H41N7O2
-
SMILES
O=C(N[C@@H]1CC[C@H](C2=NC(C=CC(OCCCN3CCNCC3)=C4)=C4N2)CC1)CNCC(N5)=CC6=C5C=CC=C6
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)