Ethyl 4-(piperazin-1-yl)benzoate
Based on 1 Customer Validation
Ethyl 4-(piperazin-1-yl)benzoate is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- CAS No.: 80518-57-6
- Formula: C13H18N2O2
- Molecular Weight:234.30
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
PROTACs contain two different ligands connected by a linker; one is a ligand for an E627 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 80518-57-6
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Appearance Solid
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Molecular Weight 234.30
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Formula C13H18N2O2
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Color Off-white to yellow
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SMILES
O=C(OCC)C1=CC=C(C=C1)N2CCNCC2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (426.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (241 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 4.2680 mL | 21.3402 mL | 42.6803 mL | 106.7008 mL |
| 5 mM | 0.8536 mL | 4.2680 mL | 8.5361 mL | 21.3402 mL | |
| 10 mM | 0.4268 mL | 2.1340 mL | 4.2680 mL | 10.6701 mL | |
| 15 mM | 0.2845 mL | 1.4227 mL | 2.8454 mL | 7.1134 mL | |
| 20 mM | 0.2134 mL | 1.0670 mL | 2.1340 mL | 5.3350 mL | |
| 25 mM | 0.1707 mL | 0.8536 mL | 1.7072 mL | 4.2680 mL | |
| 30 mM | 0.1423 mL | 0.7113 mL | 1.4227 mL | 3.5567 mL | |
| 40 mM | 0.1067 mL | 0.5335 mL | 1.0670 mL | 2.6675 mL | |
| 50 mM | 0.0854 mL | 0.4268 mL | 0.8536 mL | 2.1340 mL | |
| 60 mM | 0.0711 mL | 0.3557 mL | 0.7113 mL | 1.7783 mL | |
| 80 mM | 0.0534 mL | 0.2668 mL | 0.5335 mL | 1.3338 mL | |
| 100 mM | 0.0427 mL | 0.2134 mL | 0.4268 mL | 1.0670 mL |
Ethyl 4-(piperazin-1-yl)benzoate Related Classifications
HY-77779 Related Classifications
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