2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Phenylacetylglutamine

Phenylacetylglutamine  (Synonyms: Phenylacetyl-L-glutamine; NSC 203800)

製品番号: HY-W050026 純度: 98.21%
COA 取扱説明書 Technical Support

Phenylacetylglutamine is a colonic microbial metabolite from amino acid fermentation.

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CAS 番号 : 28047-15-6

容量 価格（税別） 在庫状況 数量
>無料サンプル (0.1 - 0.2 mg)   今すぐ申し込む  
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 35 在庫あり
Solution
10 mM * 1 mL in DMSO USD 35 在庫あり
Solid
5 mg $32 在庫あり
10 mg $50 在庫あり
25 mg $78 在庫あり
50 mg $110 在庫あり
100 mg $154 在庫あり
200 mg   お問い合わせ  
500 mg   お問い合わせ  

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カスタマーレビュー

Based on 3 publication(s) in Google Scholar

Other Forms of Phenylacetylglutamine:

Phenylacetylglutamine 関連抗体

Top Publications Citing Use of Products
Cell Proliferation/Viability Assay
Flow Cytometry
In Vivo Efficacy Study
Cell Migration/Invasion Assay

    Phenylacetylglutamine purchased from MedChemExpress. Usage Cited in: Cell Metab. 2025 Apr 1;37(4):806-823.e6.  [Abstract]

    Phenylacetylglutamine (PAGln, 50 mg/kg/day; i.p.) attenuated the inhibitory effect of anti-PD-1 on tumor growth in C57BL/6 SPF mice.

    Phenylacetylglutamine purchased from MedChemExpress. Usage Cited in: Respir Res. 2025 May 24;26(1):196.  [Abstract]

    BMSCs were treated the metabolites (UA [180, 360, 720 µM], NMDA [5, 50, 100 µM], Phenylacetylglutamine [PAG, 0.32, 3.2, 7.2 µM]) for 48 h respectively, and cell viability was detected by MTT assay. The results showed that Phenylacetylglutamin (PAG, 0.32–7.2 µM; 48 h) was non-toxic to BMSCs.

    Phenylacetylglutamine purchased from MedChemExpress. Usage Cited in: Respir Res. 2025 May 24;26(1):196.  [Abstract]

    Phenylacetylglutamin (PAG, 3.6–7.2 µM; 24 h) significantly promoted the migration ability of BMSCs.

    Phenylacetylglutamine purchased from MedChemExpress. Usage Cited in: Respir Res. 2025 May 24;26(1):196.  [Abstract]

    Phenylacetylglutamin (7.2 µM; 24 h) significantly promoted the migration ability of BMSCs.

    Phenylacetylglutamine purchased from MedChemExpress. Usage Cited in: Biomolecules. 2022 Aug 15;12(8):1120.

    Phenylacetylglutamine (PAGln, 100 μM, 24 h) intervention significantly increased ROS generation (1.44 vs. 0.80 fold change; p = 0.011), and apoptosis (56.25 vs. 49.76 %, p = 0.002) in mouse HL-1 cells.

    Endogenous Metabolite アイソフォーム固有の製品をすべて表示:

    すべてのアイソフォームを表示
    Human Endogenous Metabolite Microbial Metabolite

    • 生物活性

    • 純度とドキュメンテーション

    • 参考文献

    • カスタマーレビュー

    製品説明

    Phenylacetylglutamine is a colonic microbial metabolite from amino acid fermentation.

    IC50 & Target

    Microbial Metabolite

     

    Human Endogenous Metabolite

     

    体外実験

    Phenylacetylglutamine is a colonic microbial metabolite from amino acid fermentation. It results from glutamine conjugation of phenylacetic acid, which is almost exclusively derived from the microbial conversion of phenylalanine[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Phenylacetylglutamine 関連抗体
    分子量

    264.28

    分子式

    C13H16N2O4
    CAS 番号
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    O=C([C@H](CCC(N)=O)NC(CC1=CC=CC=C1)=O)O
    Structure Classification
    Initial Source
    輸送条件

    Room temperature in continental US; may vary elsewhere.
    保管条件
    Powder -20°C 3 years
      4°C 2 years
    In solvent -80°C 6 months
      -20°C 1 month
    溶剤 & 溶解度
    体外: 

    DMSO : 100 mg/mL (378.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

    H2O : 25 mg/mL (94.60 mM; Need ultrasonic)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 3.7839 mL 18.9193 mL 37.8387 mL
    5 mM 0.7568 mL 3.7839 mL 7.5677 mL
    10 mM 0.3784 mL 1.8919 mL 3.7839 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • Molarity Calculator

    • Dilution Calculator

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass
    =
    Concentration
    ×
    Volume
    ×
    Molecular Weight *

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    一般には略語で表示されます：C1V1 = C2V2

    濃度 （開始）

    C1

    ×
    体積 （開始）

    V1

    =
    濃度 （終了）

    C2

    ×
    体積 （終了）

    V2

    体内:

    Select the appropriate dissolution method based on your experimental animal and administration route.

    For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
    To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
    The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

    • Protocol 1

      Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

      Solubility: ≥ 2.08 mg/mL (7.87 mM); Clear solution

      This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).

      Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

      Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
    • Protocol 2

      Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

      Solubility: ≥ 2.08 mg/mL (7.87 mM); Clear solution

      This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).

      Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

      Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.

    For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
    The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

    • Protocol 1

      Add each solvent one by one:  PBS

      Solubility: 50 mg/mL (189.19 mM); Clear solution; Need ultrasonic

    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    純度とドキュメンテーション

    純度: 99.02%

    COA (245 KB)

    取扱説明書 (2659 KB)
    参考文献

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O / DMSO 1 mM 3.7839 mL 18.9193 mL 37.8387 mL 94.5966 mL
    5 mM 0.7568 mL 3.7839 mL 7.5677 mL 18.9193 mL
    10 mM 0.3784 mL 1.8919 mL 3.7839 mL 9.4597 mL
    15 mM 0.2523 mL 1.2613 mL 2.5226 mL 6.3064 mL
    20 mM 0.1892 mL 0.9460 mL 1.8919 mL 4.7298 mL
    25 mM 0.1514 mL 0.7568 mL 1.5135 mL 3.7839 mL
    30 mM 0.1261 mL 0.6306 mL 1.2613 mL 3.1532 mL
    40 mM 0.0946 mL 0.4730 mL 0.9460 mL 2.3649 mL
    50 mM 0.0757 mL 0.3784 mL 0.7568 mL 1.8919 mL
    60 mM 0.0631 mL 0.3153 mL 0.6306 mL 1.5766 mL
    80 mM 0.0473 mL 0.2365 mL 0.4730 mL 1.1825 mL
    DMSO 100 mM 0.0378 mL 0.1892 mL 0.3784 mL 0.9460 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    Phenylacetylglutamine Related Classifications

    • Molarity Calculator

    • Dilution Calculator

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    質量   濃度   体積   分子量 *
    = × ×

    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    一般には略語で表示されます：C1V1 = C2V2

    濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
    × = ×
    C1   V1   C2   V2
    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Phenylacetylglutamine28047-15-6NSC 203800 Phenylacetyl-L-glutamineNSC203800NSC-203800Endogenous MetaboliteInhibitorinhibitorinhibit

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    製品名:
    Phenylacetylglutamine
    製品番号:
    HY-W050026
    数量:
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