Phenylacetylglutamine sodium
Based on 3 publication(s) in Google Scholar
Phenylacetylglutamine (sodium) can be obtained from the hydrolysis of Antineoplaston A10. Phenylacetylglutamine (sodium) exhibits antineoplastic activity in breast carcinoma tissue culture. Phenylacetylglutamine (sodium) exerts low actue and chronic toxicity in mouse model. Phenylacetylglutamine (sodium) can be studied in research on breast cancer.
For research use only. We do not sell to patients.
- CAS No.: 104771-87-1
- Formula: C13H15N2NaO4
- Molecular Weight:286.26
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Phenylacetylglutamine sodium
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In Vivo Efficacy Study
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Cell Proliferation/Viability Assay
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Cell Migration/Invasion Assay
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Cell Migration/Invasion Assay
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Flow Cytometry
All Endogenous Metabolite Isoforms
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Biological Activity
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Microbial Metabolite |
Human Endogenous Metabolite |
Chemical Information
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CAS No. 104771-87-1
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Molecular Weight 286.26
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Formula C13H15N2NaO4
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SMILES
O=C(CC1=CC=CC=C1)N[C@H](C(O[Na])=O)CCC(N)=O
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Synonyms
NSC 203800 sodium; Phenylacetyl-L-glutamine sodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (3)
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Journal Impact Factor
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Most Recent
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Cell Metab
Interplay between gut microbial communities and metabolites modulates pan-cancer immunotherapy responses. [Abstract]2025 Apr 1;37(4):806-823.e6. PMID: 39909032
Phenylacetylglutamine sodium purchased from MedChemExpress. Usage Cited in: Cell Metab. 2025 Apr 1;37(4):806-823.e6. [Abstract]
Phenylacetylglutamine (PAGln, 50 mg/kg/day; i.p.) attenuated the inhibitory effect of anti-PD-1 on tumor growth in C57BL/6 SPF mice.
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Respir Res
Phenylacetylglutamine produced from injury lung alveolar epithelial cells promotes the function of BMSCs by regulating NONRATT006276.2/Mapt pathway. [Abstract]2025 May 24;26(1):196. PMID: 40413470
Phenylacetylglutamine sodium purchased from MedChemExpress. Usage Cited in: Respir Res. 2025 May 24;26(1):196. [Abstract]
BMSCs were treated the metabolites (UA [180, 360, 720 µM], NMDA [5, 50, 100 µM], Phenylacetylglutamine [PAG, 0.32, 3.2, 7.2 µM]) for 48 h respectively, and cell viability was detected by MTT assay. The results showed that Phenylacetylglutamin (PAG, 0.32–7.2 µM; 48 h) was non-toxic to BMSCs.
Phenylacetylglutamine sodium purchased from MedChemExpress. Usage Cited in: Respir Res. 2025 May 24;26(1):196. [Abstract]
Phenylacetylglutamin (PAG, 3.6–7.2 µM; 24 h) significantly promoted the migration ability of BMSCs.
Phenylacetylglutamine sodium purchased from MedChemExpress. Usage Cited in: Respir Res. 2025 May 24;26(1):196. [Abstract]
Phenylacetylglutamin (7.2 µM; 24 h) significantly promoted the migration ability of BMSCs.
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Biomolecules
PAGln, an Atrial Fibrillation-Linked Gut Microbial Metabolite, Acts as a Promoter of Atrial Myocyte Injury. [Abstract]2022 Aug 15;12(8):1120. PMID: 36009014
Phenylacetylglutamine sodium purchased from MedChemExpress. Usage Cited in: Biomolecules. 2022 Aug 15;12(8):1120. [Abstract]
Phenylacetylglutamine (PAGln, 100 μM, 24 h) intervention significantly increased ROS generation (1.44 vs. 0.80 fold change; p = 0.011), and apoptosis (56.25 vs. 49.76 %, p = 0.002) in mouse HL-1 cells.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)