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  4. Phenylacetylglutamine sodium

Phenylacetylglutamine sodium  (Synonyms: NSC 203800 sodium; Phenylacetyl-L-glutamine sodium)

Cat. No.: HY-W050026A
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Phenylacetylglutamine (sodium) can be obtained from the hydrolysis of Antineoplaston A10. Phenylacetylglutamine (sodium) exhibits antineoplastic activity in breast carcinoma tissue culture. Phenylacetylglutamine (sodium) exerts low actue and chronic toxicity in mouse model. Phenylacetylglutamine (sodium) can be studied in research on breast cancer.

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CAS No. : 104771-87-1

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Phenylacetylglutamine sodium Related Antibodies

Top Publications Citing Use of Products
Cell Proliferation/Viability Assay
Flow Cytometry
In Vivo Efficacy Study
Cell Migration/Invasion Assay

    Phenylacetylglutamine sodium purchased from MedChemExpress. Usage Cited in: Cell Metab. 2025 Apr 1;37(4):806-823.e6.  [Abstract]

    Phenylacetylglutamine (PAGln, 50 mg/kg/day; i.p.) attenuated the inhibitory effect of anti-PD-1 on tumor growth in C57BL/6 SPF mice.

    Phenylacetylglutamine sodium purchased from MedChemExpress. Usage Cited in: Respir Res. 2025 May 24;26(1):196.  [Abstract]

    BMSCs were treated the metabolites (UA [180, 360, 720 µM], NMDA [5, 50, 100 µM], Phenylacetylglutamine [PAG, 0.32, 3.2, 7.2 µM]) for 48 h respectively, and cell viability was detected by MTT assay. The results showed that Phenylacetylglutamin (PAG, 0.32–7.2 µM; 48 h) was non-toxic to BMSCs.

    Phenylacetylglutamine sodium purchased from MedChemExpress. Usage Cited in: Respir Res. 2025 May 24;26(1):196.  [Abstract]

    Phenylacetylglutamin (PAG, 3.6–7.2 µM; 24 h) significantly promoted the migration ability of BMSCs.

    Phenylacetylglutamine sodium purchased from MedChemExpress. Usage Cited in: Respir Res. 2025 May 24;26(1):196.  [Abstract]

    Phenylacetylglutamin (7.2 µM; 24 h) significantly promoted the migration ability of BMSCs.

    Phenylacetylglutamine sodium purchased from MedChemExpress. Usage Cited in: Biomolecules. 2022 Aug 15;12(8):1120.

    Phenylacetylglutamine (PAGln, 100 μM, 24 h) intervention significantly increased ROS generation (1.44 vs. 0.80 fold change; p = 0.011), and apoptosis (56.25 vs. 49.76 %, p = 0.002) in mouse HL-1 cells.

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    Description

    Phenylacetylglutamine (sodium) can be obtained from the hydrolysis of Antineoplaston A10. Phenylacetylglutamine (sodium) exhibits antineoplastic activity in breast carcinoma tissue culture. Phenylacetylglutamine (sodium) exerts low actue and chronic toxicity in mouse model. Phenylacetylglutamine (sodium) can be studied in research on breast cancer[1].

    IC50 & Target

    Microbial Metabolite

     

    Human Endogenous Metabolite

     

    Molecular Weight

    286.26

    Formula

    C13H15N2NaO4
    CAS No.
    SMILES

    O=C(CC1=CC=CC=C1)N[C@H](C(O[Na])=O)CCC(N)=O
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.
    Purity & Documentation
    References
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    Phenylacetylglutamine sodium Related Classifications

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    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Phenylacetylglutamine104771-87-1NSC 203800Phenylacetyl-L-glutamineNSC203800NSC-203800Endogenous MetaboliteBiochemical Assay ReagentsInhibitorinhibitorinhibit

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