2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0443
    N-Methylcytisine 486-86-2 99.81%
    N-Methylcytisine (Caulophylline), a tricyclic quinolizidine alkaloid, exerts hypoglycaemic, analgesic and anti-inflammatory activities. N-methylcytisine is a selective ligand of nicotinic receptors of acetylcholine in the central nervous system and has a high affinity (Kd = 50 nM) to nicotinic acetylcholine receptors (nAChR) from squid optical ganglia.
    N-Methylcytisine
  • HY-N0875
    IKarisoside A 55395-07-8 99.44%
    IKarisoside A (Icarisoside-A) is a natural flavonol glycoside and has anti-inflammatory properties.
    IKarisoside A
  • HY-N1072
    Wilforgine 37239-47-7 99.67%
    Wilforgine is a bioactive sesquiterpene alkaloid in Tripterygium wilfordii Hook. F. Wilforgine can induce microstructural and ultrastructural changes in the muscles of Mythimna separata larvae, and the sites of action are proposed to be calcium receptors or channels in the muscular system.
    Wilforgine
  • HY-N1402
    Oxysophoridine 54809-74-4 99.18%
    Oxysophoridine (Sophoridine N-oxide) is a bioactive alkaloid extracted from the Sophora alopecuroides Linn. Oxysophoridine (Sophoridine N-oxide) shows anti inflammatory, anti oxidative stress and anti apoptosis effects.
    Oxysophoridine
  • HY-N1403
    Tigogenin 77-60-1 98.0%
    Tigogenin is a steroidal sapogenins. Tigogenin can inhibit adipocytic differentiation and induce osteoblastic differentiation in mouse bone marrow stromal cells. Tigogenin can inhibit cells proliferation and induce apoptosis. Tigogenin can be used for the researches of cancer, inflammation, immunology, metabolic and cardiovascular disease, such as mammary gland carcinoma, rheumatoid arthritis, osteoporosis and atherosclerosis.
    Tigogenin
  • HY-N1413
    Noricaritin 5240-95-9 99.04%
    Noricaritin is a flavonoid sourced from roots of Epimedium brevicornu Maxim.
    Noricaritin
  • HY-N1521
    Rehmannic acid 467-81-2
    Rehmannic acid (lantadene A) is a compound isolated from Lantana camara. Rehmannic acid shows considerable in vitro antioxidant, free radical scavenging capacity activities in a dose dependant manner. Rehmannic acid is a promising candidate for use as an antioxidant and hepatoprotective agent.
    Rehmannic acid
  • HY-N1973
    Sennoside D 37271-17-3 98.36%
    Sennoside D is an anthraquinone glycoside, found in leaves and pods of Senna (Cassia angustifolia).
    Sennoside D
  • HY-N1980
    3'-Hydroxypuerarin 117060-54-5 99.44%
    3'-Hydroxypuerarin is an isoflavone isolated from the roots of Pueraria lobata (Willd.) Ohwi. 3'-Hydroxypuerarin is a antioxidant, which shows marked ONOO(-), NO•, total ROS scavenging activities.
    3'-Hydroxypuerarin
  • HY-N2000
    Bellidifolin 2798-25-6 99.74%
    Bellidifolin is an orally active compound with antiproliferative, anti-inflammatory and antioxidant properties. Bellidifolin modulates key signaling pathways including STAT3, PI3K-Akt, mTOR and BRD4, and inhibits the viral protein R (Vpr). Bellidifolin induces cell cycle arrest and apoptosis, exerts significant antifibrotic effects, and protects the heart, liver and nervous system. Bellidifolin is applicable to the research of various diseases such as lung cancer, non-alcoholic fatty liver disease, myocardial hypertrophy and ischemic cranial nerve injury.
    Bellidifolin
  • HY-N2005
    Cycleanine 518-94-5 99.80%
    Cycleanine is a potent vascular selective Calcium antagonist. Cycleanine has analgesic, muscle relaxant and anti-inflammatory activities. Cycleanine has potential for anti-ovarian cancer acting through the apoptosis pathway.
    Cycleanine
  • HY-N2008
    Luteolin 5-O-glucoside 20344-46-1 ≥98.0%
    Luteolin 5-O-glucoside, a major flavonoidfrom Cirsium maackii, possesses anti-inflammatory activity. Luteolin 5-O-glucoside inhibits LPS-induced NO production and t-BHP-induced ROS generation. Luteolin 5-O-glucoside suppresses the expression of iNOS and COX-2 in macrophages.
    Luteolin 5-O-glucoside
  • HY-N2052
    (-)-Zeylenol 78804-17-8
    (-)-Zeylenol, isaolated from stems of Uvaria grandiflora, possesses anti-inflammatory and anticancer activities.
    (-)-Zeylenol
  • HY-N2074
    Picrinine 4684-32-6 99.98%
    Picrinine, an akuammiline alkaloid, is isolated from the leaves of Alstonia scholaris. Picrinine exhibits anti-inflammatory activity through inhibition of the 5-lipoxygenase enzyme.
    Picrinine
  • HY-N2136
    Cochinchinenin A 1057666-04-2 98.83%
    Cochinchinenin A serves as the fundamental component responsible for the analgesic properties of Dragon's Blood.
    Cochinchinenin A
  • HY-N2138
    Buddlejasaponin IVb 152580-79-5 99.78%
    Buddlejasaponin IVb (Compound 2), a triterpene saponin isolated from Clinopodium chinense (Benth.) O. Kuntze, Compound 2 has hemostasis efficacy, shortens thrombin time (TT) by 20.6 %.
    Buddlejasaponin IVb
  • HY-N2152
    Rhodojaponin III 26342-66-5 99.83%
    Rhodojaponin III is a diterpenoid from the leaves of Rhododendron molle with anti-inflammatory activity.
    Rhodojaponin III
  • HY-N2244
    Hosenkoside M 161016-51-9 99.75%
    Hosenkoside M is a baccharane glycoside isolated from the seeds of impatiens balsamina.
    Hosenkoside M
  • HY-N2276
    Nodakenetin 495-32-9 99.66%
    Nodakenetin, isolated from Angelica decursiva, possesses antioxidant anti-inflammatory activities. Nodakenetin has the potential to be an antiarthritic and nerve tonic.
    Nodakenetin
  • HY-N2285
    Fabiatrin 18309-73-4 99.81%
    Fabiatrin is a natural product that can be isolated from Przewalskia tangutica.
    Fabiatrin
Cat. No. Product Name / Synonyms Application Reactivity