1. Immunology/Inflammation
    NF-κB
    Metabolic Enzyme/Protease
  2. NO Synthase
    Reactive Oxygen Species
  3. Luteolin 5-O-glucoside

Luteolin 5-O-glucoside 

Cat. No.: HY-N2008 Purity: >98.0%
Handling Instructions

Luteolin 5-O-glucoside, a major flavonoidfrom Cirsium maackii, possesses anti-inflammatory activity. Luteolin 5-O-glucoside inhibits LPS-induced NO production and t-BHP-induced ROS generation. Luteolin 5-O-glucoside suppresses the expression of iNOS and COX-2 in macrophages.

For research use only. We do not sell to patients.

Luteolin 5-O-glucoside Chemical Structure

Luteolin 5-O-glucoside Chemical Structure

CAS No. : 20344-46-1

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5 mg USD 720 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Luteolin 5-O-glucoside, a major flavonoidfrom Cirsium maackii, possesses anti-inflammatory activity. Luteolin 5-O-glucoside inhibits LPS-induced NO production and t-BHP-induced ROS generation. Luteolin 5-O-glucoside suppresses the expression of iNOS and COX-2 in macrophages[1].

In Vitro

Luteolin 5-O-glucoside, at a non-toxic concentration, inhibits LPS-induced NO production and t-BHP-induced ROS generation in a dose-dependent manner in RAW 264.7 cells. Luteolin 5-O-glucoside also suppresses the expression of iNOS and COX-2 in LPS-stimulated macrophages[1].

Molecular Weight

448.38

Formula

C₂₁H₂₀O₁₁

CAS No.

20344-46-1

SMILES

O=C1C=C(C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC(O[[email protected]]4[[email protected]@H]([[email protected]]([[email protected]@H]([[email protected]@H](CO)O4)O)O)O)=C13

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

References
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Keywords:

Luteolin 5-O-glucosideNO SynthaseReactive Oxygen SpeciesNitric oxide synthasesNOSReactiveoxygenspeciesROSNitricoxideNOanti-inflammatoryInhibitorinhibitorinhibit

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Luteolin 5-O-glucoside
Cat. No.:
HY-N2008
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