2. Signaling Pathways
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  4. Drug Isomer

Drug Isomer

Drug Isomer

Drug isomers are compounds with the same molecular formula but different atomic arrangements or spatial configurations. They are divided into structural isomers and stereoisomers, and have different biological activities, safety and metabolic characteristics. Drug isomers can be used as drug improvement groups or drug efficacy control groups. For example, Carvedilol has higher bioavailability and better safety than (R)-Carvedilol.

Drug Isomer Related Products (432):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-18715
    Ornidazole (Levo-)
    		98.86%
    Levo-ornidazole ((S)-Ornidazole) is the L-isomer of Ornidazole. Ornidazole (Levo-) increases GAD 65/67 expression and decreases brain Glu/GABA ratio. Ornidazole (Levo-) has a mild sedative effect. Levo-ornidazole can be used in the research of anti-anaerobic and anti-parasitic agents.
    Ornidazole (Levo-)
  • HY-113949A
    Methyl 2,3-O-Isopropylidene-β-L-ribofuranoside
    Methyl 2,3-O-Isopropylidene-β-L-ribofuranoside is an enantiomer of Methyl 2,3-O-Isopropylidene-β-D-ribofuranoside. Methyl 2,3-O-Isopropylidene-β-L-ribofuranoside is a derivative of L-ribose.
    Methyl 2,3-O-Isopropylidene-β-L-ribofuranoside
  • HY-105559A
    Viquidil hydrochloride
    		99.47%
    Viquidil hydrochloride (Quinotoxine hydrochloride), an isomer of Quinidine, is a cerebral vasodilator agent. Viquidil hydrochloride shows antithrombotic activity.
    Viquidil hydrochloride
  • HY-77111
    cis-INCB3344
    cis-INCB3344 is the isomer of INCB3344 (HY-50674), and can be used as an experimental control. INCB3344 is a potent, selective and orally bioavailable CCR2 antagonist with IC50 values of 5.1 nM (hCCR2) and 9.5 nM (mCCR2) in binding antagonism and 3.8 nM (hCCR2) and 7.8 nM (mCCR2) in antagonism of chemotaxis activity.
    cis-INCB3344
  • HY-135396
    (1S,2S)-Bortezomib
    (1S,2S)-Bortezomib (Compound Imp-D (1S,2S)) is a diastereomeric impurity of Bortezomib (HY-10227).
    (1S,2S)-Bortezomib
  • HY-112101
    Prohydrojasmon racemate
    		98.0%
    Prohydrojasmon racemate (n-Propyl dihydrojasmonate) is the racemate of Prohydrojasmon. Prohydrojasmon is a synthesized plant growth regulator.
    Prohydrojasmon racemate
  • HY-N0136A
    (±)-Taxifolin
    		99.34%
    (±)-Taxifolin ((±)-Dihydroquercetin) is the racemate of Taxifolin (HY-N0136). Taxifolin exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC50 value of 193.3 μM. Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity.
    (±)-Taxifolin
  • HY-165071
    (±)16(17)-EpDPA
    		≥99.0%
    (±)16(17)-EpDPA is the DHA homolog of (±)14(15)-EpETrE, derived via epoxidation of the 16,17-double bond of DHA.
    (±)16(17)-EpDPA
  • HY-167712
    (2R,3S)-Azelaprag
    		99.10%
    (2R,3S)-Azelaprag ((2R,3S)-AMG 986) (Example 238.0) is a precursor of an apelin receptor agonist (EC50=12 nM) and an isomer of Azelaprag (HY-109111).
    (2R,3S)-Azelaprag
  • HY-N3045
    (S,S)-Pisatin
    		98.66%
    (S,S)-Pisatin is a dimeric pterocarpan derivative. (S,S)-Pisatin can inhibit plant growth.
    (S,S)-Pisatin
  • HY-19489S
    (±)-Levomepromazine-d6
    		99.23%
    (±)-Levomepromazine-d6 ((±)-Methotrimeprazine-d6) is the deuterium labeled (±)-Levomepromazine (HY-19489). (±)-Levomepromazine ((±)-Methotrimeprazine) is the racemate of Levomepromazine (HY-B1693).
    (±)-Levomepromazine-d<sub>6</sub>
  • HY-N6020R
    (-)-Butin (Standard)
    (-)-Butin (Standard) is the analytical standard of (-)-Butin (HY-N6020). This product is intended for research and analytical applications. (-)-Butin is a enantiomer of Butin (HY-N6020B). Butin is a major biologically active flavonoid isolated from the heartwood of Dalbergia odorifera, with strong antioxidant, antiplatelet and anti-inflammatory activities.
    (-)-Butin (Standard)
  • HY-153816A
    (1R)-GLP-1 receptor agonist 12
    (1R)-GLP-1 receptor agonist 12 is the isomer of GLP-1 receptor agonist 12 (HY-153816).
    (1R)-GLP-1 receptor agonist 12
  • HY-153306A
    (S)-Zovegalisib
    		99.89%
    (S)-Zovegalisib ((S)-RLY-2608) is an S-enantiomer of of Zovegalisib (HY-153306). Zovegalisib is an orally active first-in-class allosteric mutant-selective inhibitor of PI3Ka with anti-tumor activity.
    (S)-Zovegalisib
  • HY-100181B
    (R)-PF-04991532
    		98.04%
    (R)-PF-04991532 is the R-enantiomer of PF-04991532 (HY-100181). PF-04991532 is a potent, hepatoselective glucokinase activator.
    (R)-PF-04991532
  • HY-N6065
    Praeruptorin A
    		99.57%
    Praeruptorin A ((+)-Praeruptorin A) is an orally active isomer of (±)-Praeruptorin A (HY-N0081). Praeruptorin A also acts as a Calcium channel blocker. Praeruptorin A can be isolated from Peucedanum. Praeruptorin A serves as a substrate for CYP3A4. Praeruptorin A downregulates NMDA receptors containing GluN2B and inhibits neuronal Apoptosis. Praeruptorin A mediates vasodilation, inhibits vascular hypertrophy and reduces blood pressure. Praeruptorin A can be used in research related to neurological diseases, myocardial ischemia, heart failure, exertional angina, renovascular hypertension and spontaneous hypertension.
    Praeruptorin A
  • HY-15805A
    cis-KIN-8194
    		98.89%
    cis-KIN-8194 is the cis-isomer of KIN-8194 (HY-15805)
    cis-KIN-8194
  • HY-145388B
    AU-16235
    		Control 99.54%
    AU-16235 is an inactive epimer of AU-15330. AU-16235 has no effect on cancer cell survival and growth
    AU-16235
  • HY-120751A
    (S)-TROX-1
    		99.52%
    (S)-TROX-1 is the S-enantiomer of TROX-1 (HY-120751). TROX-1 is a selective, orally active and brain-penetrant N-type calcium channel (Cav2.2) inhibitor with an IC50 value of 0.11 μM. TROX-1 exerts state-dependent and use-dependent inhibition, preferentially targets open/inactivated channels, blocks depolarization-associated calcium influx, and fully blocks calcium influx in rat dorsal root ganglion neurons. TROX-1 reverses inflammatory-induced hyperalgesia, nerve injury-induced allodynia. TROX-1 can be used for the research of pain.
    (S)-TROX-1
  • HY-124883
    R-(–)-Flecainide
    		Control 99.90%
    R-(–)-Flecainide is an orally active antiarrhythmic agent, which inhibits ventricular ectopic activity.
    R-(–)-Flecainide