R-(–)-Flecainide
Based on 1 Customer Validation
R-(–)-Flecainide is an orally active antiarrhythmic agent, which inhibits ventricular ectopic activity.
For research use only. We do not sell to patients.
- Purity: 99.90%
- CAS No.: 99495-90-6
- Formula: C17H20F6N2O3
- Molecular Weight:414.34
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Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Chloroform-induced ventricular fibrillation in mice[1]
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Dosage:9-20 mg/kg
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Administration:po, single dose
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Result:Prevented fibrillation.
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Animal Model:Ouabain induced ventricular tachycardia in mongrel dog[1]
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Dosage:1-3 mg/kg
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Administration:iv, single dose
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Result:Inhibited arrhythmias.
Chemical Information
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CAS No. 99495-90-6
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Appearance Solid
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Molecular Weight 414.34
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Formula C17H20F6N2O3
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Color White to off-white
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SMILES
O=C(C1=C(C=CC(OCC(F)(F)F)=C1)OCC(F)(F)F)NC[C@H]2CCCCN2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (241.35 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4135 mL | 12.0674 mL | 24.1348 mL | 60.3369 mL |
| 5 mM | 0.4827 mL | 2.4135 mL | 4.8270 mL | 12.0674 mL | |
| 10 mM | 0.2413 mL | 1.2067 mL | 2.4135 mL | 6.0337 mL | |
| 15 mM | 0.1609 mL | 0.8045 mL | 1.6090 mL | 4.0225 mL | |
| 20 mM | 0.1207 mL | 0.6034 mL | 1.2067 mL | 3.0168 mL | |
| 25 mM | 0.0965 mL | 0.4827 mL | 0.9654 mL | 2.4135 mL | |
| 30 mM | 0.0804 mL | 0.4022 mL | 0.8045 mL | 2.0112 mL | |
| 40 mM | 0.0603 mL | 0.3017 mL | 0.6034 mL | 1.5084 mL | |
| 50 mM | 0.0483 mL | 0.2413 mL | 0.4827 mL | 1.2067 mL | |
| 60 mM | 0.0402 mL | 0.2011 mL | 0.4022 mL | 1.0056 mL | |
| 80 mM | 0.0302 mL | 0.1508 mL | 0.3017 mL | 0.7542 mL | |
| 100 mM | 0.0241 mL | 0.1207 mL | 0.2413 mL | 0.6034 mL |
R-(–)-Flecainide Related Classifications
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