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(S)-TROX-1

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(S)-TROX-1 is the S-enantiomer of TROX-1 (HY-120751). TROX-1 is a selective, orally active and brain-penetrant N-type calcium channel (Cav2.2) inhibitor with an IC50 value of 0.11 μM. TROX-1 exerts state-dependent and use-dependent inhibition, preferentially targets open/inactivated channels, blocks depolarization-associated calcium influx, and fully blocks calcium influx in rat dorsal root ganglion neurons. TROX-1 reverses inflammatory-induced hyperalgesia, nerve injury-induced allodynia. TROX-1 can be used for the research of pain.

For research use only. We do not sell to patients.

  • Purity: 99.52%
  • CAS No.: 2751591-42-9
  • Formula: C22H16ClFN6O
  • Molecular Weight:434.85
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • (S)-TROX-1 Chemical Structure
    (S)-TROX-1 Chemical Structure
CAS No.: 2751591-42-9
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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  • (S)-TROX-1 Chemical Structure
    (S)-TROX-1 Chemical Structure
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  • (S)-TROX-1