(S)-Zovegalisib
Based on 1 Customer Validation
(S)-Zovegalisib ((S)-RLY-2608) is an S-enantiomer of of Zovegalisib (HY-153306). Zovegalisib is an orally active first-in-class allosteric mutant-selective inhibitor of PI3Ka with anti-tumor activity.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99.68%
- CAS. Nr.: 2733573-93-6
- Formel: C29H14ClF5N6O2
- Molecular Weight:608.91
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 2733573-93-6
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Appearance Solid
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Molecular Weight 608.91
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Formel C29H14ClF5N6O2
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Color White to off-white
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SMILES
O=C1N[C@H](C2=CC(F)=CC=C2Cl)C(C1=C3)=C(NC(C4=CC(F)=CC(C(F)(F)F)=C4)=O)C=C3C5=C(C#N)N6C(C=C5)=NC=N6
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Synonyms
(S)-RLY-2608
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 40 mg/mL (65.69 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Reinheit & Dokumentation
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Data Sheet (275 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.6423 mL | 8.2114 mL | 16.4228 mL | 41.0570 mL |
| 5 mM | 0.3285 mL | 1.6423 mL | 3.2846 mL | 8.2114 mL | |
| 10 mM | 0.1642 mL | 0.8211 mL | 1.6423 mL | 4.1057 mL | |
| 15 mM | 0.1095 mL | 0.5474 mL | 1.0949 mL | 2.7371 mL | |
| 20 mM | 0.0821 mL | 0.4106 mL | 0.8211 mL | 2.0528 mL | |
| 25 mM | 0.0657 mL | 0.3285 mL | 0.6569 mL | 1.6423 mL | |
| 30 mM | 0.0547 mL | 0.2737 mL | 0.5474 mL | 1.3686 mL | |
| 40 mM | 0.0411 mL | 0.2053 mL | 0.4106 mL | 1.0264 mL | |
| 50 mM | 0.0328 mL | 0.1642 mL | 0.3285 mL | 0.8211 mL | |
| 60 mM | 0.0274 mL | 0.1369 mL | 0.2737 mL | 0.6843 mL |
(S)-Zovegalisib Related Classifications
HY-153306A Related Classifications
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