(S)-Zovegalisib
Based on 1 Customer Validation
(S)-Zovegalisib ((S)-RLY-2608) is an S-enantiomer of of Zovegalisib (HY-153306). Zovegalisib is an orally active first-in-class allosteric mutant-selective inhibitor of PI3Ka with anti-tumor activity.
For research use only. We do not sell to patients.
- Purity: 99.89%
- CAS No.: 2733573-93-6
- Formula: C29H14ClF5N6O2
- Molecular Weight:608.91
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 2733573-93-6
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Appearance Solid
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Molecular Weight 608.91
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Formula C29H14ClF5N6O2
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Color White to off-white
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SMILES
O=C1N[C@H](C2=CC(F)=CC=C2Cl)C(C1=C3)=C(NC(C4=CC(F)=CC(C(F)(F)F)=C4)=O)C=C3C5=C(C#N)N6C(C=C5)=NC=N6
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Synonyms
(S)-RLY-2608
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 40 mg/mL (65.69 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6423 mL | 8.2114 mL | 16.4228 mL | 41.0570 mL |
| 5 mM | 0.3285 mL | 1.6423 mL | 3.2846 mL | 8.2114 mL | |
| 10 mM | 0.1642 mL | 0.8211 mL | 1.6423 mL | 4.1057 mL | |
| 15 mM | 0.1095 mL | 0.5474 mL | 1.0949 mL | 2.7371 mL | |
| 20 mM | 0.0821 mL | 0.4106 mL | 0.8211 mL | 2.0528 mL | |
| 25 mM | 0.0657 mL | 0.3285 mL | 0.6569 mL | 1.6423 mL | |
| 30 mM | 0.0547 mL | 0.2737 mL | 0.5474 mL | 1.3686 mL | |
| 40 mM | 0.0411 mL | 0.2053 mL | 0.4106 mL | 1.0264 mL | |
| 50 mM | 0.0328 mL | 0.1642 mL | 0.3285 mL | 0.8211 mL | |
| 60 mM | 0.0274 mL | 0.1369 mL | 0.2737 mL | 0.6843 mL |