β-Glycerophosphate (disodium salt pentahydrate)

Name: β-Glycerophosphate disodium salt pentahydrate
Brand: MedChemExpress
SKU: HY-D0886
Rating: 5.0 (30 reviews)

製品番号: HY-D0886 純度: 99.99%: Data Sheet SDS COA 取扱説明書
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β-Glycerophosphate disodium salt pentahydrate is a bioactive endogenous metabolite and a phosphatase inhibitor. β-Glycerophosphate disodium salt pentahydrate plays an important role in inducing and maintaining osteoblast differentiation, mineral metabolism and signal transduction, and can be used as a drug carrier to form heat-sensitive hydrogels. β-Glycerophosphate disodium salt hydrate accelerates the calcification of vascular smooth muscle cells.

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CAS 番号 : 13408-09-8

容量	価格（税別）	在庫状況	数量
5 g	$25	在庫あり	Estimated Time of Arrival: December 31
10 g	$33	在庫あり	Estimated Time of Arrival: December 31
25 g	$50	在庫あり	Estimated Time of Arrival: December 31
50 g		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 30 publication(s) in Google Scholar

Other Forms of β-Glycerophosphate disodium salt pentahydrate:

β-Glycerophosphate disodium salt hydrate 在庫あり
β-Glycerophosphate-d₅ sodium salt hydrate お問い合わせ

顧客検証

Cell Imaging/Staining

: β-Glycerophosphate disodium salt pentahydrate purchased from MedChemExpress. Usage Cited in: Mater Today Bio. 2025 Jun 21:33:102009. [Abstract]; β-Glycerophosphate disodium salt pentahydrate (10 mM; 1 week). DPA@NM@CTZE boosts the mineralization and differentiation capabilities of osteoblasts in a palmitic acid (Pa) environment.

: β-Glycerophosphate disodium salt pentahydrate purchased from MedChemExpress. Usage Cited in: Biomaterials. 2024 Aug 15:313:122756. [Abstract]; Representative images of Alizarin Red staining on 14 and 21 days of BMSCs seeded on porous tantalum scaffolds and cultured in osteogenic induction medium containing 1 M β-glycerophosphate (β-Glycerophosphate disodium salt pentahydrate) and 10 mM ascorbic acid ( L-Ascorbic acid).

: β-Glycerophosphate disodium salt pentahydrate purchased from MedChemExpress. Usage Cited in: J Mol Histol. 2024 Aug;55(4):503-512.; β-Glycerophosphate disodium salt pentahydrate (10 mM; 7-21 days). The expression levels of KLF9 (shown by immunofluorescence staining) under different induction conditions.

: β-Glycerophosphate disodium salt pentahydrate purchased from MedChemExpress. Usage Cited in: Mater Today Bio. 2023 May 18:20:100667.; β-Glycerophosphate disodium salt pentahydrate (10 mM; 7 days). Representative ALP staining image of BMSCs cultured on Gyroid, Cylindrical, Cubic pore scaffolds and Control in the osteogenic medium after culturing for 7 days.

: β-Glycerophosphate disodium salt pentahydrate purchased from MedChemExpress. Usage Cited in: J Mol Histol. 2021 Oct;52(5):1067-1080. [Abstract]; β-Glycerophosphate disodium salt pentahydrate (10 mM; 48 h). Western blot showed that the expression of ALP, BMP2, phosphorylation-STAT3 and STAT3 protein in VSMCs treated by different chemical compound.

Endogenous Metabolite アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

Human Endogenous Metabolite Microbial Metabolite

ERK アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

ERK ERK1 ERK2 ERK5 ERK8

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

IC₅₀ & Target

ERK1

ERK2

体外実験

β-Glycerophosphate disodium salt pentahydrate, as a phosphate source of the bone mineral hydroxyapatite, can promote osteogenic differentiation and further induce osteogenic gene expression through phosphorylation of the cytokinase-associated kinase ERK1/2^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

306.11

分子式

C₃H₁₇Na₂O₁₁P

CAS 番号

13408-09-8

Appearance

Solid

Color

White to off-white

SMILES

OCC(OP(O[Na])(O[Na])=O)CO.[5H2O]

Structure Classification

Others

Initial Source

Endogenous metabolite

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

溶剤 & 溶解度

体外:

H₂O : 83.33 mg/mL (272.22 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.2668 mL	16.3340 mL	32.6680 mL
5 mM	0.6534 mL	3.2668 mL	6.5336 mL
10 mM	0.3267 mL	1.6334 mL	3.2668 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

体内:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 100 mg/mL (326.68 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

純度とドキュメンテーション

純度: 99.99%

Select Batch:

データシート (278 KB) SDS (394 KB)

COA (253 KB) HNMR (248 KB) RP-HPLC (243 KB) MS (70 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Belfield A, et al. Inhibition of the nucleotidase effect of alkaline phosphatase by beta-glycerophosphate. Nature. 1968 Jul 6;219(5149):73-5. [Content Brief]

[2]. Langenbach F, et al. Effects of dexamethasone, ascorbic acid and β-glycerophosphate on the osteogenic differentiation of stem cells in vitro. Stem Cell Res Ther. 2013;4(5):117.

[3]. Chung CH, et al. Mechanism of action of beta-glycerophosphate on bone cell mineralization. Calcif Tissue Int. 1992;51(4):305-311. [Content Brief]

[4]. Li C, et al. Efficacy, pharmacokinetics, and biodistribution of thermosensitive chitosan/β-glycerophosphate hydrogel loaded with docetaxel. AAPS PharmSciTech. 2014 Apr;15(2):417-24.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	3.2668 mL	16.3340 mL	32.6680 mL	81.6700 mL
	5 mM	0.6534 mL	3.2668 mL	6.5336 mL	16.3340 mL
	10 mM	0.3267 mL	1.6334 mL	3.2668 mL	8.1670 mL
	15 mM	0.2178 mL	1.0889 mL	2.1779 mL	5.4447 mL
	20 mM	0.1633 mL	0.8167 mL	1.6334 mL	4.0835 mL
	25 mM	0.1307 mL	0.6534 mL	1.3067 mL	3.2668 mL
	30 mM	0.1089 mL	0.5445 mL	1.0889 mL	2.7223 mL
	40 mM	0.0817 mL	0.4083 mL	0.8167 mL	2.0417 mL
	50 mM	0.0653 mL	0.3267 mL	0.6534 mL	1.6334 mL
	60 mM	0.0544 mL	0.2722 mL	0.5445 mL	1.3612 mL
	80 mM	0.0408 mL	0.2042 mL	0.4083 mL	1.0209 mL
	100 mM	0.0327 mL	0.1633 mL	0.3267 mL	0.8167 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.