2. Metabolic Enzyme/Protease Stem Cell/Wnt MAPK/ERK Pathway
  3. Phosphatase Endogenous Metabolite ERK
  4. β-Glycerophosphate disodium salt hydrate

β-Glycerophosphate disodium salt hydrate 

Cat. No.: HY-126304 Purity: 99.92%
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β-Glycerophosphate disodium salt pentahydrate is a bioactive endogenous metabolite and a phosphatase inhibitor. β-Glycerophosphate disodium salt pentahydrate plays an important role in inducing and maintaining osteoblast differentiation, mineral metabolism and signal transduction, and can be used as a drug carrier to form heat-sensitive hydrogels. β-Glycerophosphate disodium salt hydrate accelerates the calcification of vascular smooth muscle cells.

For research use only. We do not sell to patients.

CAS No. : 154804-51-0

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Based on 30 publication(s) in Google Scholar

Other Forms of β-Glycerophosphate disodium salt hydrate:

β-Glycerophosphate disodium salt hydrate Related Antibodies

Top Publications Citing Use of Products

    β-Glycerophosphate disodium salt hydrate purchased from MedChemExpress. Usage Cited in: Mater Today Bio. 2025 Jun 21:33:102009.  [Abstract]

    β-Glycerophosphate disodium salt pentahydrate (10 mM; 1 week). DPA@NM@CTZE boosts the mineralization and differentiation capabilities of osteoblasts in a palmitic acid (Pa) environment.

    β-Glycerophosphate disodium salt hydrate purchased from MedChemExpress. Usage Cited in: Biomaterials. 2024 Aug 15:313:122756.  [Abstract]

    Representative images of Alizarin Red staining on 14 and 21 days of BMSCs seeded on porous tantalum scaffolds and cultured in osteogenic induction medium containing 1 M β-glycerophosphate (β-Glycerophosphate disodium salt pentahydrate) and 10 mM ascorbic acid ( L-Ascorbic acid).

    β-Glycerophosphate disodium salt hydrate purchased from MedChemExpress. Usage Cited in: J Mol Histol. 2024 Aug;55(4):503-512.

    β-Glycerophosphate disodium salt pentahydrate (10 mM; 7-21 days). The expression levels of KLF9 (shown by immunofluorescence staining) under different induction conditions.

    β-Glycerophosphate disodium salt hydrate purchased from MedChemExpress. Usage Cited in: Mater Today Bio. 2023 May 18:20:100667.

    β-Glycerophosphate disodium salt pentahydrate (10 mM; 7 days). Representative ALP staining image of BMSCs cultured on Gyroid, Cylindrical, Cubic pore scaffolds and Control in the osteogenic medium after culturing for 7 days.

    β-Glycerophosphate disodium salt hydrate purchased from MedChemExpress. Usage Cited in: J Mol Histol. 2021 Oct;52(5):1067-1080.  [Abstract]

    β-Glycerophosphate disodium salt pentahydrate (10 mM; 48 h). Western blot showed that the expression of ALP, BMP2, phosphorylation-STAT3 and STAT3 protein in VSMCs treated by different chemical compound.

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    Human Endogenous Metabolite Microbial Metabolite

    View All ERK Isoform Specific Products:

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    ERK ERK1 ERK2 ERK5 ERK8

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    Description

    β-Glycerophosphate disodium salt pentahydrate is a bioactive endogenous metabolite and a phosphatase inhibitor. β-Glycerophosphate disodium salt pentahydrate plays an important role in inducing and maintaining osteoblast differentiation, mineral metabolism and signal transduction, and can be used as a drug carrier to form heat-sensitive hydrogels. β-Glycerophosphate disodium salt hydrate accelerates the calcification of vascular smooth muscle cells[1][2][3].

    IC50 & Target

    ERK1

     

    ERK2

     

    In Vitro

    β-Glycerophosphate disodium salt pentahydrate, as a phosphate source of the bone mineral hydroxyapatite, can promote osteogenic differentiation and further induce osteogenic gene expression through phosphorylation of the cytokinase-associated kinase ERK1/2[3].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    β-Glycerophosphate disodium salt hydrate Related Antibodies
    Formula

    C3H7O6PNa2.xH2O
    CAS No.
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    OCC(OP(O[Na])(O[Na])=O)CO.[H]O[H].[x]
    Structure Classification
    Initial Source
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    4°C, sealed storage, away from moisture and light

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

    Solvent & Solubility
    In Vitro: 

    H2O : 175 mg/mL (Need ultrasonic)

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    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    In Vivo:

    For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
    The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

    • Protocol 1

      Add each solvent one by one:  PBS

      Solubility: 25 mg/mL; Clear solution; Need ultrasonic and warming

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    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    Purity & Documentation

    Purity: 99.92%

    SDS (393 KB)

    COA (253 KB) HNMR (252 KB) RP-HPLC (253 KB) MS (70 KB)

    Handling Instructions (2659 KB)
    References
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    β-Glycerophosphate disodium salt hydrate Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    β-Glycerophosphate disodium salt154804-51-0PhosphataseEndogenous MetaboliteERKExtracellular signal regulated kinasesCalcification Endogenous metaboliteBone cellsMineral metabolismInhibitorinhibitorinhibit

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