1. Metabolic Enzyme/Protease
    Autophagy
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  2. RAR/RXR
    Autophagy
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  3. Acitretin

Acitretin (Synonyms: Ro 10-1670)

Cat. No.: HY-B0107 Purity: 99.79%
Handling Instructions

Acitretin (Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. Acitretin also can be used for the research of Alzheimer’s disease.

For research use only. We do not sell to patients.

Acitretin Chemical Structure

Acitretin Chemical Structure

CAS No. : 55079-83-9

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 169 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 169 In-stock
Estimated Time of Arrival: December 31
Solid
100 mg USD 154 In-stock
Estimated Time of Arrival: December 31
200 mg USD 252 In-stock
Estimated Time of Arrival: December 31
500 mg USD 456 In-stock
Estimated Time of Arrival: December 31
1 g   Get quote  
5 g   Get quote  

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Customer Review

Based on 2 publication(s) in Google Scholar

Other Forms of Acitretin:

Top Publications Citing Use of Products
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Description

Acitretin (Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. Acitretin also can be used for the research of Alzheimer’s disease[1][2][3].

In Vivo

Acitretin (10 mg/kg; i.p. for 7 days) increases IL-6 in the central nervous system of Alzheimer’s disease model mice[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

326.43

Formula

C21H26O3

CAS No.
SMILES

CC(/C=C/C(C(C)=CC(OC)=C1C)=C1C)=C\C=C\C(C)=C\C(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 20 mg/mL (61.27 mM; Need ultrasonic)

H2O : 0.67 mg/mL (2.05 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0634 mL 15.3172 mL 30.6344 mL
5 mM 0.6127 mL 3.0634 mL 6.1269 mL
10 mM 0.3063 mL 1.5317 mL 3.0634 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: 2 mg/mL (6.13 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2 mg/mL (6.13 mM); Suspended solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2 mg/mL (6.13 mM); Clear solution

*All of the co-solvents are available by MCE.
References
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  • Molarity Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

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Acitretin
Cat. No.:
HY-B0107
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