1. Metabolic Enzyme/Protease
  2. Thrombin
  3. Argatroban

Argatroban (Synonyms: MD-805; MCI-9038; Argipidine)

Cat. No.: HY-B0375
Handling Instructions

Argatroban (MD-805) is a direct, selective thrombin inhibitor.

For research use only. We do not sell to patients.

Argatroban Chemical Structure

Argatroban Chemical Structure

CAS No. : 74863-84-6

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Description

Argatroban (MD-805) is a direct, selective thrombin inhibitor.

IC50 & Target

Thrombin[1].

In Vitro

Argatroban (MD-805) may have a complementary effect for preventing thrombus formation without aggravating bleeding tendency because of its monotarget specificity to thrombin. Administration (0.5 to 2 micrograms/kg/min) of Argatroban (MD-805) is a safe anticoagulant for left heart bypass in repairs of traumatic aortic rupture associated with multiple organ injuries[1]. Argatroban (MD-805), as compared with heparin, appears to enhance reperfusion with TPA in patients with AMI, particularly in those patients with delayed presentation. The incidences of major bleeding and adverse clinical outcome were lower in the patients receiving argatroban[2].

Clinical Trial
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

508.63

Formula

C₂₃H₃₆N₆O₅S

CAS No.

74863-84-6

SMILES

O=C([[email protected]@H]1N(C([[email protected]@H](NS(=O)(C2=CC=CC3=C2NCC(C)C3)=O)CCCNC(N)=N)=O)CC[[email protected]@H](C)C1)O

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
Argatroban
Cat. No.:
HY-B0375
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Argatroban

Cat. No.: HY-B0375