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  4. Argatroban

Argatroban  (Synonyms: MD-805; MCI-9038; Argipidine)

Cat. No.: HY-B0375
Handling Instructions

Argatroban (MD-805) is a direct, selective thrombin inhibitor.

For research use only. We do not sell to patients.

Argatroban Chemical Structure

Argatroban Chemical Structure

CAS No. : 74863-84-6

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Argatroban (MD-805) is a direct, selective thrombin inhibitor.

IC50 & Target


In Vitro

Argatroban (MD-805) may have a complementary effect for preventing thrombus formation without aggravating bleeding tendency because of its monotarget specificity to thrombin. Administration (0.5 to 2 micrograms/kg/min) of Argatroban (MD-805) is a safe anticoagulant for left heart bypass in repairs of traumatic aortic rupture associated with multiple organ injuries[1]. Argatroban (MD-805), as compared with heparin, appears to enhance reperfusion with TPA in patients with AMI, particularly in those patients with delayed presentation. The incidences of major bleeding and adverse clinical outcome were lower in the patients receiving argatroban[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Argatroban can be used in animal modeling to establish endogenous intestinal thrombus model.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight







Room temperature in continental US; may vary elsewhere.


Please store the product under the recommended conditions in the Certificate of Analysis.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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