1. Metabolic Enzyme/Protease
  2. Thrombin
  3. Argatroban

Argatroban (Synonyms: MD-805; MCI-9038; Argipidine)

Cat. No.: HY-B0375
Handling Instructions

Argatroban (MD-805) is a direct, selective thrombin inhibitor.

For research use only. We do not sell to patients.

Argatroban Chemical Structure

Argatroban Chemical Structure

CAS No. : 74863-84-6

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Description

Argatroban (MD-805) is a direct, selective thrombin inhibitor.

IC50 & Target

Thrombin[1].

In Vitro

Argatroban (MD-805) may have a complementary effect for preventing thrombus formation without aggravating bleeding tendency because of its monotarget specificity to thrombin. Administration (0.5 to 2 micrograms/kg/min) of Argatroban (MD-805) is a safe anticoagulant for left heart bypass in repairs of traumatic aortic rupture associated with multiple organ injuries[1]. Argatroban (MD-805), as compared with heparin, appears to enhance reperfusion with TPA in patients with AMI, particularly in those patients with delayed presentation. The incidences of major bleeding and adverse clinical outcome were lower in the patients receiving argatroban[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

508.63

Formula

C₂₃H₃₆N₆O₅S

CAS No.

74863-84-6

SMILES

O=C([[email protected]@H]1N(C([[email protected]@H](NS(=O)(C2=CC=CC3=C2NCC(C)C3)=O)CCCNC(N)=N)=O)CC[[email protected]@H](C)C1)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

ArgatrobanMD-805 MCI-9038 ArgipidineMD805MD 805MCI9038MCI 9038MCI-9038ThrombinInhibitorinhibitorinhibit

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Argatroban
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