Search Result

Results for "

biotinyl-

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (1) Amylin Receptor (2) Amyloid-β (4) Apoptosis (1) Bacterial (1) BCL6 (1) Biochemical Assay Reagents (26) Bombesin Receptor (2) CGRP Receptor (1) Claudin (1) Drug Derivative (2) EGFR (1) Endogenous Metabolite (1) Fluorescent Dye (7) Gap Junction Protein (1) GCGR (2) ICMT (1) Isotope-Labeled Compounds (1) Liposome (3) nAChR (1) Neurokinin Receptor (1) Neuropeptide B/W Receptor (1) NF-κB (1) PROTAC Linkers (2) Proteasome (2) Reactive Oxygen Species (ROS) (1) Sialyltransferase (1) SphK (1) Src (1) Syk (1) Thyroid Hormone Receptor (1) Transmembrane Glycoprotein (2)
By Research Areas:	Cancer (14) Cardiovascular Disease (1) Endocrinology (3) Infection (2) Inflammation/Immunology (4) Metabolic Disease (8) Neurological Disease (12)
Oligonucleotides:	Phospholipids (2)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-125658

Biotinyl tyramide 5+ Cited Publications	Fluorescent Dye	Others
Biotinyl tyramide is a biotin derivative used for tyramide signal amplification (TSA), as a reagent to amplify both immunohistochemical signals and in situ hybridization protocols. Biotinyl tyramide can be used for the research of tyramide signal amplification .

HY-P11307

Biotin-epoxomicin	Proteasome	Cancer
Biotin-epoxomicin is a Proteasome subunit binder. Biotin-epoxomicin serves as an affinity reagent for identifying proteasomal catalytic subunits, and facilitates affinity purification of active proteasomal subunits for LC-MS identification. Biotin-epoxomicin can be used to study solid tumors derived from B16 melanoma .

HY-125616

Biotinoyl tripeptide-1 biotinyl-GHK; Bio-GHK	Amyloid-β Reactive Oxygen Species (ROS)	Neurological Disease
Biotinoyl tripeptide-1 (Biotinyl-GHK) is a biotinylating reagent linked to a GHK (glycyl-L-histidyl-L-lysine) tripeptide. Biotin tripeptide-1 is a bioactive peptide with hair care (improves the appearance and feel of hair) and hair growth effects. Biotinoyl tripeptide-1 has a certain affinity for streptavidin. Biotinoyl tripeptide-1 inhibits the production of ROS and has antioxidant effects. Biotinoyl tripeptide-1 reduces the production of carbonylated amyloid-β (Aβ) and inhibits Aβ aggregation. Biotinoyl tripeptide-1 can be used in the study of neurodegenerative diseases .

HY-D0980

Biotin-DADOO biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin	Biochemical Assay Reagents	Infection
Biotin-DADOO (Biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin) is a biotin-containing amine compound and a biotinylation reagent. As an amino component, Biotin-DADOO participates in the nucleophilic ring-opening reaction of epoxidized ω-double bonds during the synthesis of biotinylated inhibitor derivatives. Biotin-DADOO can be conjugated with carboxymethyl cellulose derivatives. Biotin-DADOO is involved in the synthesis of biotin-estradiol conjugates for enzyme immunoassays. Biotin-DADOO can be used in the research of influenza A .

HY-P11306

Biotin-(Oaa)3-epoxomicin	Proteasome NF-κB	Inflammation/Immunology
Biotin-(Oaa)₃-epoxomicin is a biotin-labeled form of Epoxomicin (HY-13821), prepared by conjugating Epoxomicin with biotin via three hydrophilic oxaacetyl amino acid (Oaa) linkers. Biotin-(Oaa)₃-epoxomicin is primarily used in proteomic studies for the capture, identification and target validation of proteasome complexes, to determine the intracellular targets of epoxomicin. Epoxomicin acts as a proteasome inhibitor and NF-κB inhibitor, which effectively blocks inflammatory responses in mouse ear edema assays. It inhibits proteasome activity via covalent binding to catalytic subunits including LMP7, X, MECL1 and Z, with the strongest inhibitory effect on chymotrypsin-like activity, and does not interfere with non-proteasomal proteases such as trypsin and papain .

HY-P4928

Biotinyl-Amylin (mouse, rat)	Amylin Receptor	Metabolic Disease
Biotinyl-Amylin (mouse, rat) is a biotinylated Amylin (mouse, rat). Amylin (mouse, rat) is a 37-aminoacid pancreatic protein that exerts control over several metabolic events such as glycemia and lacticemia .

HY-P10620

GGGYK-Biotin	Bacterial	Others
GGGYK-Biotin is a substrate peptide designed to study the substrate specificity of Sortase A. GGGYK-Biotin can be used to develop Sortase A variants with different substrate specificities .

HY-P3576A

Biotin-Gastrin Releasing Peptide, human TFA	Fluorescent Dye Bombesin Receptor	Neurological Disease Cancer
Biotin-Gastrin Releasing Peptide, human TFA is a biotinylated gastrin releasing peptide (GRP). Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties .

HY-P2546

Biotin-Substance P	Neurokinin Receptor	Neurological Disease
Biotin-Substance P is the biotin tagged Substance P. Substance P (Neurokinin P) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R) .

HY-W741573

*N-Biotinyl* p-aminophenyl arsenic acid**	nAChR	Neurological Disease
N-Biotinyl p-aminophenyl arsenic acid is a bifunctional reagent that can bind to both streptavidin and dithiols. N-Biotinyl p-aminophenyl arsenic acid decreases the Rbungarotoxin-binding sites in reduced Torpedo nicotinic receptors (IC₅₀ is 10-300 nM), and protects the receptor from irreversible alkylation by bromoacetylcholine .

HY-W800797

*16:0 Biotinyl* PE** 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(biotinyl)	Liposome	Cancer
16:0 Biotinyl PE is a biotin-functionalized lipid attached to a phosphoethanolamine linked to two palmitic acid groups.

HY-130142A

Biotinyl-NH-PEG3-C3-amido-C3-COOH	PROTAC Linkers	Cancer
Biotinyl-NH-PEG3-C3-amido-C3-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-P10886

Zifogaptide	Gap Junction Protein Claudin	Inflammation/Immunology
Zifogaptide is a gap junction protein channel regulator. Zifogaptide mimics the PDZ-binding motif at the C-terminal of Claudin C and competitively interferes with the interaction between Claudin–TJP1 (ZO-1) scaffold. Zifogaptide can promote epithelial cell migration, reduce scar formation, and accelerate wound healing. Zifogaptide can be used for radiation dermatitis, skin injuries, etc .

HY-P5351A

*Hyaluronan-binding peptide, biotin* labeled TFA**	Transmembrane Glycoprotein	Inflammation/Immunology Cancer
Hyaluronan-binding peptide, biotin labeled TFA is a biological active peptide. (This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan expressed in the extracellular matrix and on cell surfaces. HA plays a role in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.) .

HY-P2491

*Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled*	Fluorescent Dye	Cardiovascular Disease Endocrinology
Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, one of three mammalian natriuretic peptides (NPs), has endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide has the potential for cardiovascular diseases research .

HY-P2136F

Biotin-COG1410 TFA	Apoptosis	Neurological Disease Inflammation/Immunology Cancer
Biotin-COG1410 TFA is a biotin labled COG1410 (HY-P2136). COG1410 is an apolipoprotein E-derived peptide and an apoptosis inhibitor. COG1410 exerts neuroprotective and antiinflammatory effects in a murine model of traumatic brain injury (TBI). COG1410 can be used for the research of neurological disease .

HY-W343597

*N-Biotinyl-1,6-hexanediaMine*	Biochemical Assay Reagents	Others
N-Biotinyl-1,6-hexanediaMine is a biotinylated biochemical assay reagent, that can be used as a biological material or organic compound for life science related research .

HY-P11118A

Biotinylated CCDC61 peptide TFA CAPture peptide, biotin-CCDC61 (334-366) TFA	Biochemical Assay Reagents	Others
Biotinylated CCDC61 peptide (CAPture peptide, biotin-CCDC61 (334-366)) TFA is a biotinylated peptide derived from the centrosomal protein CCDC61. Biotinylated CCDC61 peptide TFA specifically isolates intact centrosomes .

HY-P3844

Biotinyl-neuropeptide W-23 (human)	Transmembrane Glycoprotein Neuropeptide B/W Receptor	Neurological Disease
Biotinyl-neuropeptide W-23 (human) is a biotinylated Neuropeptide W-23 (human) (HY-P1035). Neuropeptide W-23 (human) is an agonist of NPBW1 (GPR7) and NPBW2 (GPR8) .

HY-101218

*N-Biotinyl-6-aminohexanoic acid* N-(+)-biotinyl-6-aminohexanoic acid	Sialyltransferase	Others
N-Biotinyl-6-aminohexanoic acid (N-(+)-Biotinyl-6-aminohexanoic acid) can be used to perform biotinylation .

HY-128466

*N-Biotinyl-L-cysteine*	Biochemical Assay Reagents	Others
N-Biotinyl-L-cysteine is a biotinylated biochemical assay reagent, which is used to detect avidin and biotin through a competitive binding reaction .

HY-W460118

*N-Biotinyl-5-methoxytryptamine*	Biochemical Assay Reagents	Others
N-Biotinyl-5-methoxytryptamine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P2549

Biotin-β-Amyloid (1-40)	Fluorescent Dye	Neurological Disease
Biotin-β-Amyloid (1-40) is a N-terminal-labelled biotinylated amyloid-β-(1-40) peptide.

HY-P3621

Biotinyl-Glucagon (1-29), human, bovine, porcine	GCGR	Metabolic Disease
Biotinyl-Glucagon (1-29), human, bovine, porcine is a biotinylated glucagon. Glucagon is a peptide hormone, produced by α-cells of the pancreas, can increase concentration of glucose and fatty acids in the bloodstream .

HY-W394025

Biotinyl-6-aminoquinoline	Biochemical Assay Reagents	Others
Biotinyl-6-aminoquinoline is a fluorescent biotinylated biochemical assay reagent, which can be utilized as a substrate in the assay of biotinidase activity. Biotinyl-6-aminoquinoline exhibits an excitation wanelength of 350 nm and an emission wavelength of 550 nm .

HY-P4863

Biotinyl-Amylin (human)	CGRP Receptor	Neurological Disease Metabolic Disease
Biotinyl-Amylin (human) is a biotin-labeled derivative of Amylin, amide, human (HY-P1070). Biotinyl-Amylin (human) acts as a competitive agonist for the Calcitonin Receptor (CTR) and for the Amylin receptors (AMY₁, AMY₂, and AMY₃) formed by the association of CTR with RAMP1/2/3. By mimicking endogenous human amylin, Biotinyl-Amylin (human) binds to and activates CTR and AMY receptors, thereby initiating downstream signaling pathways involving cAMP, CREB, and ERK1/2, while retaining high-affinity receptor binding and activation capabilities. Biotinyl-Amylin (human) is primarily utilized in studies investigating the metabolic regulatory mechanisms underlying obesity and diabetes; it is also applicable to pharmacological research, receptor localization studies, and ligand-binding assays related to Amylin receptors in the context of Alzheimer's disease .

HY-W800796

*18:1 Biotinyl* PE** 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(biotinyl)	Liposome	Cancer
18:1 Biotinyl PE is a biotin-functionalized lipid attached to a phosphoethanolamine linked to two oleic acid groups.

HY-130142

Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA)	PROTAC Linkers	Cancer
Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-157920

Biotin-PE-maleimide N-biotinyl-N'-[2-(N-maleimido)ethyl]piperazine	Biochemical Assay Reagents	Others
Biotin-PE-maleimide (N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine) is a bulky, membrane-impermeable, sulfhydryl-containing reagent with a relatively large molecular size. Biotin-PE-maleimide can be used for biotin labeling (such as thiol groups) and detection of proteins or other biomolecules .

HY-P4928A

Biotinyl-Amylin (mouse, rat) TFA	Amylin Receptor	Metabolic Disease
Biotinyl-Amylin (mouse, rat) TFA is a biotinylated Amylin (mouse, rat). Amylin (mouse, rat) is a 37-aminoacid pancreatic protein that exerts control over several metabolic events such as glycemia and lacticemia .

HY-P2510

Parathyroid Hormone (1-34), human, biotinylated	Thyroid Hormone Receptor	Metabolic Disease
Parathyroid Hormone (1-34), human, biotinylated is a probe for the parathyroid hormone receptor, can be used for analyzing the interaction between parathyroid hormone and parathyroid hormone receptors in living cells and for purifying hormone-receptor complexes with affinity columns .

HY-P10569

Biotin HER-2 substrate peptide	EGFR	Cancer
Biotin HER-2 substrate peptide is a substrate of Her4 and Her2/neu tyrosine kinase with a K_m value of 60 μm for Her2/neu kinase domain .

HY-13443F

*Exendin 4, biotin* labeled** Lys27(Biotin)-Exendin 4	GCGR	Others
Exendin 4, biotin labeled is a biotin labeled Exendin 4 (HY-13443). Exendin 4 is a long-acting GLP-1 receptor agonist .

HY-CE01232

Biotinyl-CoA biotinyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
Biotinyl-CoA (Biotinyl-coenzyme A) is a coenzyme A derivative .

HY-125658S

Biotinyl tyramide-d4	Isotope-Labeled Compounds	Others
Biotinyl tyramide-d₄ is a deuterated labeled Biotinyl tyramide (HY-125658). Biotinyl tyramide is a biotin derivative used for tyramide signal amplification (TSA), as a reagent to amplify both immunohistochemical signals and in situ hybridization protocols. Biotinyl tyramide can be used for the research of tyramide signal amplification .

HY-W340832

*18:1 Biotinyl* Cap PE**	Liposome	Cancer
18:1 Biotinyl Cap PE is a fluorescent lipid, which features a head group that has been altered to include biotinyl cap PE.

HY-137425

*N-Biotinyl-12-aminododecanoic acid*	Biochemical Assay Reagents	Others
N-Biotinyl-12-aminododecanoic acid is a compound formed by linking biotin and 12-aminododecanoic acid through an amide bond. N-Biotinyl-12-aminododecanoic acid is used as a biotinylation reagent to test the ligation activity of SimL .

HY-W141944

*Fmoc-Glu(biotinyl-PEG)-OH*	Amino Acid Derivatives	Others
Fmoc-Glu(biotinyl-PEG)-OH is a glutamic acid derivative .

HY-N15989

*12:0 Biotinyl* coenzyme A triammonium**	Biochemical Assay Reagents	Others
12:0 Biotinyl coenzyme A triammonium is a biotinylated lipid.

HY-P4864

Biotinyl-ACTH (1-39) (human)	Biochemical Assay Reagents	Others
Biotinyl-ACTH (1-39) (human) is abiotinylated Adrenocorticotropic Hormone (ACTH) (1-39), human (HY-P1211).

HY-W019781

Biotinylated sphingosine biotinyl-Sph	SphK	Metabolic Disease
Biotinylated sphingosine (Biotinyl-Sph) is a substrate of sphingosine kinase that can b used to detect the phosphorylation activity of sphingosine kinase 1 (SPHK1) and SPHK2 .

HY-W340471

*N-Biotinyl-4-aminobutanoic acid*	Biochemical Assay Reagents	Others
N-Biotinyl-4-aminobutanoic acid is a biotinylated biochemical assay reagent, that can be used as a biological material or organic compound for life science related research .

HY-W776972

*N-d-Biotinyl-7-amino-4-methylcoumarin*	Biochemical Assay Reagents	Others
N-d-Biotinyl-7-amino-4-methylcoumarin is a biochemical reagent.

HY-W729030

*Fmoc-Lys(biotinyl-e-aminocaproyl)-OH*	Biochemical Assay Reagents	Others
Fmoc-Lys(biotinyl-e-aminocaproyl)-OH is a biotinylated biochemical assay reagent, that can be used to develop the ferrocene-based biosensor .

HY-113930

*3-[2-N-(Biotinyl)aminoethyldithio]propanoic acid*	Biochemical Assay Reagents	Others
3-[2-N-(Biotinyl)aminoethyldithio]propanoic acid is a SS-biotin that can be utilized in cellular proximity biotinylation assays to label interactors .

HY-P3860

Biotinyl-Amyloid β-Protein (1-42) ammonium	Amyloid-β	Neurological Disease
Biotinyl-Amyloid β-Protein (1-42) ammonium is a biotinylated Amyloid β-Protein (1-42) (HY-P1363). Biotinyl-Amyloid β-Protein (1-42) ammonium can be used for the research of Aβ1-42 converts to Aβ1-40 in brain .

HY-P1032F

Biotinyl-Angiotensin I (human, mouse, rat)	Endogenous Metabolite	Endocrinology
Biotinyl-Angiotensin I (human, mouse, rat) is biotin-labeled Angiotensin I . Angiotensin I (human, mouse, rat) is the precursor to the vasoconstrictor peptide angiotensin II, cleaved by the angiotensin-converting enzyme (ACE) .

HY-P4861

Biotinyl-Ahx-Amyloid β-Protein (1-42)	Amyloid-β	Others
Biotinyl-Ahx-Amyloid β-Protein (1-42) is abiotinylated β-Amyloid (1-42), human (TFA) (HY-P1363).

HY-W674127

*N-Biotinyl-N'-Boc-1,6-hexanediamine*	Biochemical Assay Reagents	Others
N-Biotinyl-N'-Boc-1,6-hexanediamine is a biotinylated biochemical assay reagent that can be used as a biological material or organic compound for life science related research .

HY-162668

*N-Biotinyl-N'-Boc-1,4-butanediamine*	Biochemical Assay Reagents	Others
N-Biotinyl-N'-Boc-1,4-butanediamine is a biotinylated biochemical assay reagent that can be used as a biological material or organic compound for life science related research .

Cat. No.	Product Name	Type

HY-D0980

Biotin-DADOO

biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin

Biochemical Assay Reagents

Biotin-DADOO (Biotinyl-3,6-dioxaoctanediamine; EZ-Link Amine-PEO2-Biotin) is a biotin-containing amine compound and a biotinylation reagent. As an amino component, Biotin-DADOO participates in the nucleophilic ring-opening reaction of epoxidized ω-double bonds during the synthesis of biotinylated inhibitor derivatives. Biotin-DADOO can be conjugated with carboxymethyl cellulose derivatives. Biotin-DADOO is involved in the synthesis of biotin-estradiol conjugates for enzyme immunoassays. Biotin-DADOO can be used in the research of influenza A .

HY-W343597

*N-Biotinyl-1,6-hexanediaMine*	Biochemical Assay Reagents
N-Biotinyl-1,6-hexanediaMine is a biotinylated biochemical assay reagent, that can be used as a biological material or organic compound for life science related research .

HY-128466

*N-Biotinyl-L-cysteine*	Biochemical Assay Reagents
N-Biotinyl-L-cysteine is a biotinylated biochemical assay reagent, which is used to detect avidin and biotin through a competitive binding reaction .

HY-W394025

Biotinyl-6-aminoquinoline	Biochemical Assay Reagents
Biotinyl-6-aminoquinoline is a fluorescent biotinylated biochemical assay reagent, which can be utilized as a substrate in the assay of biotinidase activity. Biotinyl-6-aminoquinoline exhibits an excitation wanelength of 350 nm and an emission wavelength of 550 nm .

HY-157920

Biotin-PE-maleimide N-biotinyl-N'-[2-(N-maleimido)ethyl]piperazine	Biochemical Assay Reagents
Biotin-PE-maleimide (N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine) is a bulky, membrane-impermeable, sulfhydryl-containing reagent with a relatively large molecular size. Biotin-PE-maleimide can be used for biotin labeling (such as thiol groups) and detection of proteins or other biomolecules .

HY-137425

*N-Biotinyl-12-aminododecanoic acid*	Biochemical Assay Reagents
N-Biotinyl-12-aminododecanoic acid is a compound formed by linking biotin and 12-aminododecanoic acid through an amide bond. N-Biotinyl-12-aminododecanoic acid is used as a biotinylation reagent to test the ligation activity of SimL .

HY-W340471

*N-Biotinyl-4-aminobutanoic acid*	Biochemical Assay Reagents
N-Biotinyl-4-aminobutanoic acid is a biotinylated biochemical assay reagent, that can be used as a biological material or organic compound for life science related research .

HY-W776972

*N-d-Biotinyl-7-amino-4-methylcoumarin*	Biochemical Assay Reagents
N-d-Biotinyl-7-amino-4-methylcoumarin is a biochemical reagent.

HY-W729030

*Fmoc-Lys(biotinyl-e-aminocaproyl)-OH*	Biochemical Assay Reagents
Fmoc-Lys(biotinyl-e-aminocaproyl)-OH is a biotinylated biochemical assay reagent, that can be used to develop the ferrocene-based biosensor .

HY-W674127

*N-Biotinyl-N'-Boc-1,6-hexanediamine*	Biochemical Assay Reagents
N-Biotinyl-N'-Boc-1,6-hexanediamine is a biotinylated biochemical assay reagent that can be used as a biological material or organic compound for life science related research .

HY-162668

*N-Biotinyl-N'-Boc-1,4-butanediamine*	Biochemical Assay Reagents
N-Biotinyl-N'-Boc-1,4-butanediamine is a biotinylated biochemical assay reagent that can be used as a biological material or organic compound for life science related research .

HY-170459

*18:1-12:0 Biotin* PE** 1-Oleoyl-2-(12-biotinyl(aminododecanoyl))-sn-glycero-3-phosphoethanolamine	Biochemical Assay Reagents
18:1-12:0 Biotin PE (1-Oleoyl-2-(12-biotinyl(aminododecanoyl))-sn-glycero-3-phosphoethanolamine) can be used to prepare liposomes .

HY-173381A

Cholesteryl-PEG1000-Biotin Cholesteryl biotinyl(polyethyleneglycol)-1000 carbamate	Biochemical Assay Reagents
Cholesteryl-PEG1000-Biotin is a lipid product. Cholesteryl-PEG1000-Biotin is a cholesterol backbone attached to one side of a PEG unit and a Biotin unit on the other side. Biotin is an enzyme cofactor that can be used to label proteins, and PEG is a low-toxic, hydrophilic, water-soluble polymer. Cholesteryl-PEG1000-Biotin can be used for drug circulation time studies .

Cat. No.	Product Name	Target	Research Area

HY-P11307

Biotin-epoxomicin	Proteasome	Cancer
Biotin-epoxomicin is a Proteasome subunit binder. Biotin-epoxomicin serves as an affinity reagent for identifying proteasomal catalytic subunits, and facilitates affinity purification of active proteasomal subunits for LC-MS identification. Biotin-epoxomicin can be used to study solid tumors derived from B16 melanoma .

HY-125616

Biotinoyl tripeptide-1 biotinyl-GHK; Bio-GHK	Amyloid-β Reactive Oxygen Species (ROS)	Neurological Disease
Biotinoyl tripeptide-1 (Biotinyl-GHK) is a biotinylating reagent linked to a GHK (glycyl-L-histidyl-L-lysine) tripeptide. Biotin tripeptide-1 is a bioactive peptide with hair care (improves the appearance and feel of hair) and hair growth effects. Biotinoyl tripeptide-1 has a certain affinity for streptavidin. Biotinoyl tripeptide-1 inhibits the production of ROS and has antioxidant effects. Biotinoyl tripeptide-1 reduces the production of carbonylated amyloid-β (Aβ) and inhibits Aβ aggregation. Biotinoyl tripeptide-1 can be used in the study of neurodegenerative diseases .

HY-P11306

Biotin-(Oaa)3-epoxomicin	Proteasome NF-κB	Inflammation/Immunology
Biotin-(Oaa)₃-epoxomicin is a biotin-labeled form of Epoxomicin (HY-13821), prepared by conjugating Epoxomicin with biotin via three hydrophilic oxaacetyl amino acid (Oaa) linkers. Biotin-(Oaa)₃-epoxomicin is primarily used in proteomic studies for the capture, identification and target validation of proteasome complexes, to determine the intracellular targets of epoxomicin. Epoxomicin acts as a proteasome inhibitor and NF-κB inhibitor, which effectively blocks inflammatory responses in mouse ear edema assays. It inhibits proteasome activity via covalent binding to catalytic subunits including LMP7, X, MECL1 and Z, with the strongest inhibitory effect on chymotrypsin-like activity, and does not interfere with non-proteasomal proteases such as trypsin and papain .

HY-P4941

Biotinyl-α-CGRP (mouse, rat)	Peptides	Others
Biotinyl-α-CGRP (mouse, rat) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4946A

Biotinyl-α-CGRP (human) TFA	Peptides	Others
Biotinyl-α-CGRP (human) TFA is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4928

Biotinyl-Amylin (mouse, rat)	Amylin Receptor	Metabolic Disease
Biotinyl-Amylin (mouse, rat) is a biotinylated Amylin (mouse, rat). Amylin (mouse, rat) is a 37-aminoacid pancreatic protein that exerts control over several metabolic events such as glycemia and lacticemia .

HY-P10620

GGGYK-Biotin	Bacterial	Others
GGGYK-Biotin is a substrate peptide designed to study the substrate specificity of Sortase A. GGGYK-Biotin can be used to develop Sortase A variants with different substrate specificities .

HY-P3576A

Biotin-Gastrin Releasing Peptide, human TFA	Fluorescent Dye Bombesin Receptor	Neurological Disease Cancer
Biotin-Gastrin Releasing Peptide, human TFA is a biotinylated gastrin releasing peptide (GRP). Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties .

HY-P10244F

Biotin-YVAD-FMK	Peptides	Infection
Biotin-YVAD-FMK is an inhibitor for vacuolar processing enzyme (VPE), with a 64% inhibition at 5 μM. Biotin-YVAD-FMK is an irreversible substrate for caspase 1 .

HY-P2546

Biotin-Substance P	Neurokinin Receptor	Neurological Disease
Biotin-Substance P is the biotin tagged Substance P. Substance P (Neurokinin P) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R) .

HY-P4752

*KWKHGAEIVYKSPVV-{S(GlcNAc-β-D)}-GDTSPRHLSNVK-{K(biotinyl)}-NH2*	Peptides	Others
KWKHGAEIVYKSPVV-{S(GlcNAc-β-D)}-GDTSPRHLSNVK-{K(biotinyl)}-NH2 is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P10886

Zifogaptide	Gap Junction Protein Claudin	Inflammation/Immunology
Zifogaptide is a gap junction protein channel regulator. Zifogaptide mimics the PDZ-binding motif at the C-terminal of Claudin C and competitively interferes with the interaction between Claudin–TJP1 (ZO-1) scaffold. Zifogaptide can promote epithelial cell migration, reduce scar formation, and accelerate wound healing. Zifogaptide can be used for radiation dermatitis, skin injuries, etc .

HY-P5351A

*Hyaluronan-binding peptide, biotin* labeled TFA**	Transmembrane Glycoprotein	Inflammation/Immunology Cancer
Hyaluronan-binding peptide, biotin labeled TFA is a biological active peptide. (This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan expressed in the extracellular matrix and on cell surfaces. HA plays a role in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.) .

HY-P2491

*Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled*	Fluorescent Dye	Cardiovascular Disease Endocrinology
Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, one of three mammalian natriuretic peptides (NPs), has endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide has the potential for cardiovascular diseases research .

HY-P2136F

Biotin-COG1410 TFA	Apoptosis	Neurological Disease Inflammation/Immunology Cancer
Biotin-COG1410 TFA is a biotin labled COG1410 (HY-P2136). COG1410 is an apolipoprotein E-derived peptide and an apoptosis inhibitor. COG1410 exerts neuroprotective and antiinflammatory effects in a murine model of traumatic brain injury (TBI). COG1410 can be used for the research of neurological disease .

HY-P4765

*Neuropeptide Y-Lys(biotinyl) free acid (human, rat)*	Peptides	Others
Neuropeptide Y-Lys(biotinyl) (free acid) (human, rat) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P5113A

*Histone H3 (1-21)-Gly-Gly-Lys(biotinyl) amide TFA*	Peptides	Others
Histone H3 (1-21)-Gly-Gly-Lys(biotinyl) amide TFA is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4634

*(Lys(Me)327)-Histone H3 (21-44)-Gly-Lys(biotinyl)*	Peptides	Others
(Lys(Me)327)-Histone H3 (21-44)-Gly-Lys(biotinyl) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P5115

*(Lys(Me,Me)27)-Histone H3 (21-44)-Gly-Lys(Biotinyl)*	Peptides	Others
(Lys(Me,Me)27)-Histone H3 (21-44)-Gly-Lys(Biotinyl) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4636

*(Lys(Me)34)-Histone H3 (1-21)-Gly-Gly-Lys(biotinyl) amide*	Peptides	Others
(Lys(Me)34)-Histone H3 (1-21)-Gly-Gly-Lys(biotinyl) amide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P11118A

Biotinylated CCDC61 peptide TFA CAPture peptide, biotin-CCDC61 (334-366) TFA	Biochemical Assay Reagents	Others
Biotinylated CCDC61 peptide (CAPture peptide, biotin-CCDC61 (334-366)) TFA is a biotinylated peptide derived from the centrosomal protein CCDC61. Biotinylated CCDC61 peptide TFA specifically isolates intact centrosomes .

HY-P4614

*(Lys(Ac)5,8,12,16)-Histone H4 (1-25)-Gly-Ser-Gly-Ser-Lys(biotinyl)*	Peptides	Others
(Lys(Ac)5,8,12,16)-Histone H4 (1-25)-Gly-Ser-Gly-Ser-Lys(biotinyl) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P3844

Biotinyl-neuropeptide W-23 (human)	Transmembrane Glycoprotein Neuropeptide B/W Receptor	Neurological Disease
Biotinyl-neuropeptide W-23 (human) is a biotinylated Neuropeptide W-23 (human) (HY-P1035). Neuropeptide W-23 (human) is an agonist of NPBW1 (GPR7) and NPBW2 (GPR8) .

HY-P4942

Biotinyl-Somatostatin-14	Peptides	Others
Biotinyl-Somatostatin-14 is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4946

Biotinyl-α-CGRP (human)	Peptides	Others
Biotinyl-α-CGRP (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4939

Biotinyl-KR-12 (human)	Peptides	Others
Biotinyl-KR-12 (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4945

Biotinyl-(εAhx)-Gly-Arg-Gly-Asp-Ser	Peptides	Others
Biotinyl-(εAhx)-Gly-Arg-Gly-Asp-Ser is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P5113

*Histone H3 (1-21)-Gly-Gly-Lys(biotinyl) amide*	Peptides	Others
Histone H3 (1-21)-Gly-Gly-Lys(biotinyl) amide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4929

Biotinyl-(Gln1)-Orexin A (human, mouse, rat)	Peptides	Others
Biotinyl-(Gln1)-Orexin A (human, mouse, rat) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4627

*(Lys(Me)29)-Histone H3 (1-21)-Gly-Gly-Lys(biotinyl)*	Peptides	Others
(Lys(Me)29)-Histone H3 (1-21)-Gly-Gly-Lys(biotinyl) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P2549

Biotin-β-Amyloid (1-40)	Fluorescent Dye	Neurological Disease
Biotin-β-Amyloid (1-40) is a N-terminal-labelled biotinylated amyloid-β-(1-40) peptide.

HY-P3621

Biotinyl-Glucagon (1-29), human, bovine, porcine	GCGR	Metabolic Disease
Biotinyl-Glucagon (1-29), human, bovine, porcine is a biotinylated glucagon. Glucagon is a peptide hormone, produced by α-cells of the pancreas, can increase concentration of glucose and fatty acids in the bloodstream .

HY-P4026

*K(biotinyl)-KEDVV-Abu-CS-Abu-SYKK-NH2*	Peptides	Others
K(biotinyl)-KEDVV-Abu-CS-Abu-SYKK-NH2 is a peptide that the primary structure is: Lys(biotinyl)-Lys-Glu-Asp-Val-Val-Abu-Cys-Ser-Abu-Ser-Tyr-Lys-Lys-NH2.

HY-P4863

Biotinyl-Amylin (human)	CGRP Receptor	Neurological Disease Metabolic Disease
Biotinyl-Amylin (human) is a biotin-labeled derivative of Amylin, amide, human (HY-P1070). Biotinyl-Amylin (human) acts as a competitive agonist for the Calcitonin Receptor (CTR) and for the Amylin receptors (AMY₁, AMY₂, and AMY₃) formed by the association of CTR with RAMP1/2/3. By mimicking endogenous human amylin, Biotinyl-Amylin (human) binds to and activates CTR and AMY receptors, thereby initiating downstream signaling pathways involving cAMP, CREB, and ERK1/2, while retaining high-affinity receptor binding and activation capabilities. Biotinyl-Amylin (human) is primarily utilized in studies investigating the metabolic regulatory mechanisms underlying obesity and diabetes; it is also applicable to pharmacological research, receptor localization studies, and ligand-binding assays related to Amylin receptors in the context of Alzheimer's disease .

HY-D0844F

Biotin-glutathione oxidized TFA N,N-biotinyl glutathione disulfide TFA; Biotin-GSSG TFA	Peptides	Others
Biotin-glutathione oxidized TFA ((N,N-Biotinyl glutathione disulfide TFA; Biotin-GSSG TFA) is an inducer of protein S-glutathionylation and a detection probe for S-glutathionylated proteins. Biotin-glutathione oxidized TFA forms protein-glutathione disulfide adducts, mimics components of oxidative stress, and drives protein S-glutathionylation. Biotin-glutathione oxidized TFA enables the labeling, detection, localization and purification of proteins susceptible to S-glutathionylation .

HY-P4928A

Biotinyl-Amylin (mouse, rat) TFA	Amylin Receptor	Metabolic Disease
Biotinyl-Amylin (mouse, rat) TFA is a biotinylated Amylin (mouse, rat). Amylin (mouse, rat) is a 37-aminoacid pancreatic protein that exerts control over several metabolic events such as glycemia and lacticemia .

HY-P4620

*(Lys(Me)24)-Histone H3 (1-21)-Gly-Gly-Lys(biotinyl)*	Peptides	Others
(Lys(Me)24)-Histone H3 (1-21)-Gly-Gly-Lys(biotinyl) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4616

*(Lys(Ac)12)-Histone H4 (1-21)-Gly-Gly-Lys(biotinyl)*	Peptides	Others
(Lys(Ac)12)-Histone H4 (1-21)-Gly-Gly-Lys(biotinyl) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P2510

Parathyroid Hormone (1-34), human, biotinylated	Thyroid Hormone Receptor	Metabolic Disease
Parathyroid Hormone (1-34), human, biotinylated is a probe for the parathyroid hormone receptor, can be used for analyzing the interaction between parathyroid hormone and parathyroid hormone receptors in living cells and for purifying hormone-receptor complexes with affinity columns .

HY-P10569

Biotin HER-2 substrate peptide	EGFR	Cancer
Biotin HER-2 substrate peptide is a substrate of Her4 and Her2/neu tyrosine kinase with a K_m value of 60 μm for Her2/neu kinase domain .

HY-P5351

*Hyaluronan-binding peptide, biotin* labeled**	Peptides	Others
Hyaluronan-binding peptide, biotin labeled is a biological active peptide. (This peptide is a hyaluronan-binding peptide biotinylated through a C-terminal GGGSK linker. Hyaluronan (HA) is a nonsulfated glycosaminoglycan expressed in the extracellular matrix and on cell surfaces. HA plays a role in fertilization, embryonic development, wound healing, angiogenesis, leukocyte trafficking to inflamed tissues, and cancer metastasis. This peptide has been shown to block HA binding to CD44 receptors and inhibit T cell proliferation.)

HY-13443F

*Exendin 4, biotin* labeled** Lys27(Biotin)-Exendin 4	GCGR	Others
Exendin 4, biotin labeled is a biotin labeled Exendin 4 (HY-13443). Exendin 4 is a long-acting GLP-1 receptor agonist .

HY-P4238

Biotinyl-ε-aminocaproyl-PPACK	Peptides	Others
Biotinyl-ε-aminocaproyl-PPACK is abiotinylated PPACK (HY-122542).

HY-W141944

*Fmoc-Glu(biotinyl-PEG)-OH*	Amino Acid Derivatives	Others
Fmoc-Glu(biotinyl-PEG)-OH is a glutamic acid derivative .

HY-P4864

Biotinyl-ACTH (1-39) (human)	Biochemical Assay Reagents	Others
Biotinyl-ACTH (1-39) (human) is abiotinylated Adrenocorticotropic Hormone (ACTH) (1-39), human (HY-P1211).

HY-P5076

Biotinyl-LL-37	Peptides	Others
Biotinyl-LL-37 is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P3860

Biotinyl-Amyloid β-Protein (1-42) ammonium	Amyloid-β	Neurological Disease
Biotinyl-Amyloid β-Protein (1-42) ammonium is a biotinylated Amyloid β-Protein (1-42) (HY-P1363). Biotinyl-Amyloid β-Protein (1-42) ammonium can be used for the research of Aβ1-42 converts to Aβ1-40 in brain .

HY-P1032F

Biotinyl-Angiotensin I (human, mouse, rat)	Endogenous Metabolite	Endocrinology
Biotinyl-Angiotensin I (human, mouse, rat) is biotin-labeled Angiotensin I . Angiotensin I (human, mouse, rat) is the precursor to the vasoconstrictor peptide angiotensin II, cleaved by the angiotensin-converting enzyme (ACE) .

HY-P4861

Biotinyl-Ahx-Amyloid β-Protein (1-42)	Amyloid-β	Others
Biotinyl-Ahx-Amyloid β-Protein (1-42) is abiotinylated β-Amyloid (1-42), human (TFA) (HY-P1363).

HY-P4934

Biotinyl-BNP-32 (human)	Peptides	Others
Biotinyl-BNP-32 (human) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N15989

*12:0 Biotinyl* coenzyme A triammonium**	Lipid	Biochemical Assay Reagents
12:0 Biotinyl coenzyme A triammonium is a biotinylated lipid.

HY-N16000

*12:0 Biotinyl* LPA ammonium**	Lipid	Biochemical Assay Reagents
12:0 Biotinyl LPA ammonium is a biotinylated lipid.

HY-N15975

*12:0 N-Biotinyl* fatty acid, NHS**	Lipid	Biochemical Assay Reagents
12:0 N-Biotinyl fatty acid, NHS is a biotinylated lipid. 12:0 N-Biotinyl fatty acid, NHS contains NHS groups that react with ammonia to form ester bonds .

Cat. No.	Product Name	Chemical Structure

HY-125658S

Biotinyl tyramide-d4
Biotinyl tyramide-d₄ is a deuterated labeled Biotinyl tyramide (HY-125658). Biotinyl tyramide is a biotin derivative used for tyramide signal amplification (TSA), as a reagent to amplify both immunohistochemical signals and in situ hybridization protocols. Biotinyl tyramide can be used for the research of tyramide signal amplification .

Cat. No.	Product Name		Classification

HY-W800797

*16:0 Biotinyl* PE** 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(biotinyl)		Phospholipids
16:0 Biotinyl PE is a biotin-functionalized lipid attached to a phosphoethanolamine linked to two palmitic acid groups.

HY-W340832

*18:1 Biotinyl* Cap PE**		Phospholipids
18:1 Biotinyl Cap PE is a fluorescent lipid, which features a head group that has been altered to include biotinyl cap PE.

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