Biotinoyl tripeptide-1
Based on 1 Customer Validation
Biotinoyl tripeptide-1 (Biotinyl-GHK) is a biotinylating reagent linked to a GHK (glycyl-L-histidyl-L-lysine) tripeptide. Biotin tripeptide-1 is a bioactive peptide with hair care (improves the appearance and feel of hair) and hair growth effects. Biotinoyl tripeptide-1 has a certain affinity for streptavidin. Biotinoyl tripeptide-1 inhibits the production of ROS and has antioxidant effects. Biotinoyl tripeptide-1 reduces the production of carbonylated amyloid-β (Aβ) and inhibits Aβ aggregation. Biotinoyl tripeptide-1 can be used in the study of neurodegenerative diseases.
For research use only. We do not sell to patients.
- Purity: 99.02%
- CAS No.: 299157-54-3
- Formula: C24H38N8O6S
- Molecular Weight:566.67
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Biotinoyl tripeptide-1 (2 mM) can inhibit the binding of HABA to streptavidin (IC50: 30 µM), indicating that it has a higher affinity for streptavidin[2].
Biotinoyl tripeptide-1 (0-30 μM, 45 min) dose-dependently alters the oxidative activity of ascorbic acid (ASC) induced by Cu-Aβ complexes by coordinating with copper ions and reducing the generation of ROS[2].
Biotinoyl tripeptide-1 (0-120 μM, 100 min) effectively inhibits the production of carbonylated amyloid β in acrolein-induced Aβ1-16[2].
Biotinoyl tripeptide-1 (20 μM, 50 h) inhibits the amyloid aggregation of Aβ in Aβ42[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 299157-54-3
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Appearance Solid
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Molecular Weight 566.67
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Formula C24H38N8O6S
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Color White to off-white
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Synonyms
Biotinyl-GHK; Bio-GHK
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Sequence
{Biotinyl}-Gly-His-Lys
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Sequence Shortening
{Biotinyl}-GHK
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 87.5 mg/mL (154.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Wang L, et al. Overview of Peptides and Their Potential Roles in Skin Health and Beauty. J Pept Sci. 2025 Feb;31(2):e3668. [Content Brief]
[2]. Tosto R, et al. New Biotinylated GHK and Related Copper(II) Complex: Antioxidant and Antiglycant Properties In Vitro against Neurodegenerative Disorders. Molecules. 2023 Sep 20;28(18):6724. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7647 mL | 8.8235 mL | 17.6470 mL | 44.1174 mL |
| 5 mM | 0.3529 mL | 1.7647 mL | 3.5294 mL | 8.8235 mL | |
| 10 mM | 0.1765 mL | 0.8823 mL | 1.7647 mL | 4.4117 mL | |
| 15 mM | 0.1176 mL | 0.5882 mL | 1.1765 mL | 2.9412 mL | |
| 20 mM | 0.0882 mL | 0.4412 mL | 0.8823 mL | 2.2059 mL | |
| 25 mM | 0.0706 mL | 0.3529 mL | 0.7059 mL | 1.7647 mL | |
| 30 mM | 0.0588 mL | 0.2941 mL | 0.5882 mL | 1.4706 mL | |
| 40 mM | 0.0441 mL | 0.2206 mL | 0.4412 mL | 1.1029 mL | |
| 50 mM | 0.0353 mL | 0.1765 mL | 0.3529 mL | 0.8823 mL | |
| 60 mM | 0.0294 mL | 0.1471 mL | 0.2941 mL | 0.7353 mL | |
| 80 mM | 0.0221 mL | 0.1103 mL | 0.2206 mL | 0.5515 mL | |
| 100 mM | 0.0176 mL | 0.0882 mL | 0.1765 mL | 0.4412 mL |
Biotinoyl tripeptide-1 Related Classifications
HY-125616 Related Classifications
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