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  5. Glycyl-L-histidyl-L-lysine

Glycyl-L-histidyl-L-lysine  (Synonyms: GHK; Tripeptide-1)

Cat. No.: HY-P0046 Purity: 99.89%
COA
SDS
Handling Instructions Technical Support

Glycyl-L-histidyl-L-lysine is a tripeptide consisting of glycine, L-histidine and L-lysine residues joined in sequence. Glycyl-L-histidyl-L-lysine is a hepatotropic immunosuppressor and shows anxiolytic effect. Glycyl-L-histidyl-L-lysine and its copper complexes show good skin tolerance.

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Custom Peptide Synthesis

Glycyl-L-histidyl-L-lysine

Glycyl-L-histidyl-L-lysine 화학구조

CAS No. : 49557-75-7

사이즈 가격 재고 수량
1 g 해외재고보유
5 g 해외재고보유
10 g 해외재고보유
25 g 해외재고보유
50 g   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 2 publication(s) in Google Scholar

Glycyl-L-histidyl-L-lysine Related Antibodies

Top Publications Citing Use of Products

2 Publications Citing Use of MCE Glycyl-L-histidyl-L-lysine

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

Glycyl-L-histidyl-L-lysine is a tripeptide consisting of glycine, L-histidine and L-lysine residues joined in sequence. Glycyl-L-histidyl-L-lysine is a hepatotropic immunosuppressor and shows anxiolytic effect. Glycyl-L-histidyl-L-lysine and its copper complexes show good skin tolerance[1][2][3].

In Vitro

Glycyl-L-histidyl-L-lysine and its copper complexes and saccharomyces/copper ferment on secretion of pro-inflammatory IL-6 in normal human dermal fibroblasts NHDF cell line[1].
Glycyl-L-histidyl-L-lysine and its copper complexes decreases TNF-α-dependent IL-6 secretion in fibroblasts[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Glycyl-L-histidyl-L-lysine Related Antibodies
In Vivo

Glycyl-L-histidyl-L-lysine (intraperitoneal injection; 1.5, 5, 50, 150, and 450 mg/kg; 10 times ) can stimulate mitotic activity of hepatocytes and dose-dependently suppresse immune reactivity[2].
Glycyl-L-histidyl-L-lysine (intraperitoneal injection; 0.5, 5, and 50 μg/kg) can produce an anxiolytic effect in the elevated plus maze test[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
분자량

340.38

화학식

C14H24N6O4
CAS No.
Appearance

Solid

Color

White to off-white

선적

Room temperature in continental US; may vary elsewhere.
보관

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

용액&용해도
In Vitro: 

H2O : 100 mg/mL (293.79 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9379 mL 14.6893 mL 29.3786 mL
5 mM 0.5876 mL 2.9379 mL 5.8757 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
순도&문서

Purity: 99.89%

SDS (393 KB)

COA (249 KB) HNMR (266 KB) LCMS (86 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.9379 mL 14.6893 mL 29.3786 mL 73.4465 mL
5 mM 0.5876 mL 2.9379 mL 5.8757 mL 14.6893 mL
10 mM 0.2938 mL 1.4689 mL 2.9379 mL 7.3446 mL
15 mM 0.1959 mL 0.9793 mL 1.9586 mL 4.8964 mL
20 mM 0.1469 mL 0.7345 mL 1.4689 mL 3.6723 mL
25 mM 0.1175 mL 0.5876 mL 1.1751 mL 2.9379 mL
30 mM 0.0979 mL 0.4896 mL 0.9793 mL 2.4482 mL
40 mM 0.0734 mL 0.3672 mL 0.7345 mL 1.8362 mL
50 mM 0.0588 mL 0.2938 mL 0.5876 mL 1.4689 mL
60 mM 0.0490 mL 0.2448 mL 0.4896 mL 1.2241 mL
80 mM 0.0367 mL 0.1836 mL 0.3672 mL 0.9181 mL
100 mM 0.0294 mL 0.1469 mL 0.2938 mL 0.7345 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Glycyl-L-histidyl-L-lysine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Glycyl-L-histidyl-L-lysine49557-75-7GHK Tripeptide-1Tripeptide1Tripeptide 1Tripeptide-1Othershepatotropic immunosuppressoranxiolytic effectskin toleranceInhibitorinhibitorinhibit

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상품명:
Glycyl-L-histidyl-L-lysine
Cat. No.:
HY-P0046
수량:
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SAFETY DATA SHEET (SDS)

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