49557-75-7
49557-75-7
Chemical Structure
Glycyl-L-histidyl-L-lysine
Synonym(s): GHK; Tripeptide-1
- CAS No.: 49557-75-7
- Formula:C14H24N6O4
- Molecular Weight:340.38
IUPAC Name: glycyl-L-histidyl-L-lysine
InChIKey: MVORZMQFXBLMHM-QWRGUYRKSA-N
SMILES: NCCCC[C@@H](C(O)=O)NC([C@H](CC1=CNC=N1)NC(CN)=O)=O
Biological Activity: Glycyl-L-histidyl-L-lysine is a tripeptide consisting of glycine, L-histidine and L-lysine residues joined in sequence. Glycyl-L-histidyl-L-lysine is a hepatotropic immunosuppressor and shows anxiolytic effect. Glycyl-L-histidyl-L-lysine and its copper complexes show good skin tolerance[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Glycyl-L-histidyl-L-lysine | 99.89% | Glycyl-L-histidyl-L-lysine is a tripeptide consisting of glycine, L-histidine and L-lysine residues joined in sequence. Glycyl-L-histidyl-L-lysine is a hepatotropic immunosuppressor and shows anxiolytic effect. Glycyl-L-histidyl-L-lysine and its copper complexes show good skin tolerance. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.93
HY-W010989Gly-His-Lys acetate -
Similarity Score 0.81
HY-125153Bursin -
Similarity Score 0.77
HY-P0100AHK -
Similarity Score 0.75
HY-W013870(S)-2-(2-(2-Aminoacetamido)acetamido)-3-(1H-imidazol-4-yl)propanoic acid -
Similarity Score 0.75
HY-W787749L-Histidyl-L-lysine hydrobromide -
Similarity Score 0.75
HY-P4604H-His-Lys-OH -
Similarity Score 0.74
HY-114883Homocarnosine -
Similarity Score 0.72
HY-114883AHomocarnosine TFA -
Similarity Score 0.71
HY-P4840Ac-Phe-Lys-OH -
Explore the MedChemAI to find more analogs
References
- [1]. Arkadiusz Gruchlik, et al. Effect of Gly-Gly-His, Gly-His-Lys and their copper complexes on TNF-alpha-dependent IL-6 secretion in normal human dermal fibroblasts. Acta Pol Pharm. 2012 Nov-Dec;69(6):1303-6. [Content Brief]
- [2]. M Yu Smakhtin, et al. Tripeptide Gly-His-Lys is a hepatotropic immunosuppressor. Bull Exp Biol Med. 2002 Jun;133(6):586-7. [Content Brief]
- [3]. I Bobyntsev, et al. Anxiolytic effects of Gly-His-Lys peptide and its analogs. Bull Exp Biol Med. 2015 Apr;158(6):726-8. [Content Brief]
