Tripeptide Gly-His-Lys is a hepatotropic immunosuppressor

  • Bull Exp Biol Med. 2002 Jun;133(6):586-7. doi: 10.1023/a:1020242127443.
M Yu Smakhtin  1 ,  L A Sever'yanova ,  A I Konoplya ,  I A Shveinov
Affiliations
PMID: 12447473 DOI: 10.1023/a:1020242127443
Abstract

Ten intraperitoneal injections of tripeptide Gly-His-Lys in doses of 1.5, 5, 50, 150, and 450 mg/kg stimulated mitotic activity of hepatocytes and dose-dependently suppressed immune reactivity (number of antibody-producing cells and delayed-type hypersensitivity reaction).

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