Dipeptide diaminobutyroyl benzylamide diacetate
Based on 1 Customer Validation
Dipeptide diaminobutyroyl benzylamide diacetate, a Wagerlin-1-mimicking peptide, is a nAChR antagonist. Dipeptide diaminobutyroyl benzylamide diacetate mimics Waglerin-1 to block neuromuscular junction nicotinic acetylcholine receptors, partially inhibits neuronal signal transduction, and relaxes muscles. Dipeptide diaminobutyroyl benzylamide diacetate reduces appearance of facial wrinkles linked to repeated muscle movement.Dipeptide diaminobutyroyl benzylamide diacetate can be used for the research of mild-to-moderate fine and coarse periocular and perioral wrinkles and periorbital ageing.
For research use only. We do not sell to patients.
- Purity: 99.72%
- CAS No.: 823202-99-9
- Formula: C23H37N5O7
- Molecular Weight:495.57
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Dipeptide diaminobutyroyl benzylamide diacetate is an anti-wrinkle polypeptide that can be used in cosmetic research[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 823202-99-9
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Appearance Solid
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Molecular Weight 495.57
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Formula C23H37N5O7
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Color White to off-white
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Sequence
{beta-Ala}-Pro-{Dab-NHBzl}
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Sequence Shortening
{beta-Ala}-P-{Dab-NHBzl}
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (201.79 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (279 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Trookman NS, et al. Immediate and Long-term Clinical Benefits of a Topical Treatment for Facial Lines and Wrinkles. J Clin Aesthet Dermatol. 2009;2(3):38-43. [Content Brief]
[2]. D'Arcangelis A, et al. In vitro, ex vivo, instrumental and clinical evaluation of a topical cream on the signs of periorbital ageing. Int J Cosmet Sci. 2025;47(1):18-30. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0179 mL | 10.0894 mL | 20.1788 mL | 50.4470 mL |
| 5 mM | 0.4036 mL | 2.0179 mL | 4.0358 mL | 10.0894 mL | |
| 10 mM | 0.2018 mL | 1.0089 mL | 2.0179 mL | 5.0447 mL | |
| 15 mM | 0.1345 mL | 0.6726 mL | 1.3453 mL | 3.3631 mL | |
| 20 mM | 0.1009 mL | 0.5045 mL | 1.0089 mL | 2.5223 mL | |
| 25 mM | 0.0807 mL | 0.4036 mL | 0.8072 mL | 2.0179 mL | |
| 30 mM | 0.0673 mL | 0.3363 mL | 0.6726 mL | 1.6816 mL | |
| 40 mM | 0.0504 mL | 0.2522 mL | 0.5045 mL | 1.2612 mL | |
| 50 mM | 0.0404 mL | 0.2018 mL | 0.4036 mL | 1.0089 mL | |
| 60 mM | 0.0336 mL | 0.1682 mL | 0.3363 mL | 0.8408 mL | |
| 80 mM | 0.0252 mL | 0.1261 mL | 0.2522 mL | 0.6306 mL | |
| 100 mM | 0.0202 mL | 0.1009 mL | 0.2018 mL | 0.5045 mL |
- Dipeptide diaminobutyroyl benzylamide diacetate
- 823202-99-9
- nAChR
- periocular wrinkles
- Waglerin-1
- facial wrinkles
- perioral wrinkles
- periorbital ageing
- neuromuscular junction nicotinic acetylcholine receptors
- nicotinic acetylcholine receptor antagonist
- neuronal signal transduction
- muscle contraction inhibitor
- Inhibitor
- inhibitor
- inhibit