ICMT-IN-54
ICMT-IN-54 (compound 7c) is an adamantyl analogue and an ICMT inhibitor (IC50=12.4 μM), which can inhibit ICMT Methylation. ICMT-in-54 inhibits BFC (N-biotinyl-(6-aminohexanoic)-S-farnesyl-L-cysteine) methylation in saccharomyces cerevisiae expressing ICMT, which is an indirect effect of inhibiting ICMT methylation.
For research use only. We do not sell to patients.
- CAS No.: 908856-14-4
- Formula: C29H45NO3S
- Molecular Weight:487.74
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 12.4 μM (human ICMT)[1]
Chemical Information
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CAS No. 908856-14-4
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Molecular Weight 487.74
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Formula C29H45NO3S
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SMILES
C/C(C)=C/CC/C(C)=C/CC/C(C)=C/CSC[C@@H](C(O)=O)NC(C12CC3CC(CC(C3)C2)C1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)