Biotinyl-NH-PEG3-C3-amido-C3-COOH
Based on 1 Customer Validation
Biotinyl-NH-PEG3-C3-amido-C3-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.25%
- CAS No.: 1202761-21-4
- Formula: C25H44N4O8S
- Molecular Weight:560.70
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1202761-21-4
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Appearance Solid
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Molecular Weight 560.70
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Formula C25H44N4O8S
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Color White to off-white
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SMILES
OC(CCCC(NCCCOCCOCCOCCCNC(CCCC[C@H]1[C@]2([H])[C@](NC(N2)=O)([H])CS1)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 250 mg/mL (445.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Methanol : ≥ 100 mg/mL (178.35 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Methanol / DMSO | 1 mM | 1.7835 mL | 8.9174 mL | 17.8348 mL | 44.5871 mL |
| 5 mM | 0.3567 mL | 1.7835 mL | 3.5670 mL | 8.9174 mL | |
| 10 mM | 0.1783 mL | 0.8917 mL | 1.7835 mL | 4.4587 mL | |
| 15 mM | 0.1189 mL | 0.5945 mL | 1.1890 mL | 2.9725 mL | |
| 20 mM | 0.0892 mL | 0.4459 mL | 0.8917 mL | 2.2294 mL | |
| 25 mM | 0.0713 mL | 0.3567 mL | 0.7134 mL | 1.7835 mL | |
| 30 mM | 0.0594 mL | 0.2972 mL | 0.5945 mL | 1.4862 mL | |
| 40 mM | 0.0446 mL | 0.2229 mL | 0.4459 mL | 1.1147 mL | |
| 50 mM | 0.0357 mL | 0.1783 mL | 0.3567 mL | 0.8917 mL | |
| 60 mM | 0.0297 mL | 0.1486 mL | 0.2972 mL | 0.7431 mL | |
| 80 mM | 0.0223 mL | 0.1115 mL | 0.2229 mL | 0.5573 mL | |
| 100 mM | 0.0178 mL | 0.0892 mL | 0.1783 mL | 0.4459 mL |
Biotinyl-NH-PEG3-C3-amido-C3-COOH Related Classifications
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