1. PROTAC
  2. PROTAC Linkers
  3. Biotinyl-NH-PEG3-C3-amido-C3-COOH

Biotinyl-NH-PEG3-C3-amido-C3-COOH 

Cat. No.: HY-130142A Purity: 99.31%
Handling Instructions

Biotinyl-NH-PEG3-C3-amido-C3-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Biotinyl-NH-PEG3-C3-amido-C3-COOH Chemical Structure

Biotinyl-NH-PEG3-C3-amido-C3-COOH Chemical Structure

CAS No. : 1202761-21-4

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Free Sample (0.5-1 mg)   Apply Now  
50 mg USD 114 In-stock
Estimated Time of Arrival: December 31
100 mg USD 180 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Biotinyl-NH-PEG3-C3-amido-C3-COOH:

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Description

Biotinyl-NH-PEG3-C3-amido-C3-COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

560.70

Formula

C25H44N4O8S

CAS No.
SMILES

OC(CCCC(NCCCOCCOCCOCCCNC(CCCC[[email protected]]1[[email protected]]2([H])[[email protected]](NC(N2)=O)([H])CS1)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (445.87 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7835 mL 8.9174 mL 17.8348 mL
5 mM 0.3567 mL 1.7835 mL 3.5670 mL
10 mM 0.1783 mL 0.8917 mL 1.7835 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Biotinyl-NH-PEG3-C3-amido-C3-COOH
Cat. No.:
HY-130142A
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