L-Glutamic acid-d₃

Name: L-Glutamic acid-d 3
Brand: MedChemExpress
SKU: HY-14608S8
Rating: 4.5 (0 reviews)

製品番号: HY-14608S8 純度: 99.12%: Data Sheet SDS COA 取扱説明書
FAQs
Technical Support

L-Glutamic acid-d₃ is the deuterium labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

L-Glutamic acid-d₃ 構造式

CAS 番号 : 203805-84-9

容量	価格（税別）	在庫状況	数量
1 mg	$40	在庫あり	Estimated Time of Arrival: December 31
5 mg	$80	お問い合わせ 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks	Estimated Time of Arrival: December 31
10 mg	$130	在庫あり	Estimated Time of Arrival: December 31
50 mg		お問い合わせ
100 mg		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 0 publication(s) in Google Scholar

Other Forms of L-Glutamic acid-d₃:

L-Glutamic acid 在庫あり

Endogenous Metabolite アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

Human Endogenous Metabolite Microbial Metabolite

iGluR アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

AMPA Receptor NMDA Receptor Kainate Receptor

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

体外実験

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

150.15

分子式

C₅H₆D₃NO₄

CAS 番号

203805-84-9

Unlabeled CAS

56-86-0

Appearance

Solid

Color

White to off-white

SMILES

OC(C([2H])([2H])C[C@@](N)([2H])C(O)=O)=O

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

-20°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

溶剤 & 溶解度

体外:

H₂O : 10 mg/mL (66.60 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.6600 mL	33.3000 mL	66.6001 mL
5 mM	1.3320 mL	6.6600 mL	13.3200 mL
10 mM	0.6660 mL	3.3300 mL	6.6600 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

純度とドキュメンテーション

純度: 99.26%

Select Batch:

データシート (271 KB) SDS (252 KB)

COA (248 KB) HNMR (306 KB) RP-HPLC (474 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	6.6600 mL	33.3000 mL	66.6001 mL	166.5002 mL
	5 mM	1.3320 mL	6.6600 mL	13.3200 mL	33.3000 mL
	10 mM	0.6660 mL	3.3300 mL	6.6600 mL	16.6500 mL
	15 mM	0.4440 mL	2.2200 mL	4.4400 mL	11.1000 mL
	20 mM	0.3330 mL	1.6650 mL	3.3300 mL	8.3250 mL
	25 mM	0.2664 mL	1.3320 mL	2.6640 mL	6.6600 mL
	30 mM	0.2220 mL	1.1100 mL	2.2200 mL	5.5500 mL
	40 mM	0.1665 mL	0.8325 mL	1.6650 mL	4.1625 mL
	50 mM	0.1332 mL	0.6660 mL	1.3320 mL	3.3300 mL
	60 mM	0.1110 mL	0.5550 mL	1.1100 mL	2.7750 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.