1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. L-Lysine acetate

L-Lysine acetate is an essential amino acid. L-Lysine acetate can be research for vascular calcification (VC) and Acute pancreatitis.

For research use only. We do not sell to patients.

CAS No. : 57282-49-2

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10 mM * 1 mL in Water
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Customer Review

Based on 9 publication(s) in Google Scholar

Other Forms of L-Lysine acetate:

Top Publications Citing Use of Products

    L-Lysine acetate purchased from MedChemExpress. Usage Cited in: iMetaOmics. 2025 Aug 06.

    Serum FITC-dextran levels were reduced upon L-Lysine (200 mg/kg; once daily; i.g.; 7 d) supplementation, indicating improved barrier function. L-Lysine also partially reversed the weight loss.

    L-Lysine acetate purchased from MedChemExpress. Usage Cited in: iMetaOmics. 2025 Aug 06.

    Representative immunofluorescence images of ZO-1 and red mean density analysis of ZO-1 in the ileum and colon. L-Lysine (200 mg/kg; once daily; i.g.; 7 d) supplementation significantly restored ZO-1 density.

    L-Lysine acetate purchased from MedChemExpress. Usage Cited in: iMetaOmics. 2025 Aug 06.

    Effect of L-Lysine (1.4 mM; 12 h) intervention on the scratch injury healing rate of IFN-γ pre-processed and NCM-460 cells. IFN‐γ significantly impaired healing in NCM-460 cells, and this effect was significantly alleviated by L‐Lysine.

    L-Lysine acetate purchased from MedChemExpress. Usage Cited in: iMetaOmics. 2025 Aug 06.

    Effects of L-Lysine (1.4 mM; 24 h) intervention on the ZO-1 and Occludin expression of IFN-γ pre-processed HIEC-6 cells by western blot.

    L-Lysine acetate purchased from MedChemExpress. Usage Cited in: iMetaOmics. 2025 Aug 06.

    L-Lysine (0.7-2.8 mM) dose-dependently inhibits H.biformis growth in vitro.

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    • Biological Activity

    • Purity & Documentation

    • References

    • Customer Review

    Description

    L-Lysine acetate is an essential amino acid. L-Lysine acetate can be research for vascular calcification (VC) and Acute pancreatitis[1][2].

    IC50 & Target[1][2]

    Microbial Metabolite

     

    Human Endogenous Metabolite

     

    In Vitro

    L-Lysine acetate (VSMCs) suppresses plasma iPTH and elevates plasma alanine, proline, plasma arginine, and homo arginine, thereby inhibiting apoptosis of VSMCs and mineral precipitation[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    In Vivo

    L-Lysine acetate (40 μg/kg; p.o.) ameliorates arterial calcification in adenine rats and protects the femora from osteoporotic changes in adenine rats[1].
    L-Lysine acetate (10 and 400 mg/kg; i.g. and p.o.; Male mice) inhibits pancreatic tissue damage[2].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Animal Model: Male mice[2]
    Dosage: 10 and 400 mg/kg
    Administration: Intraperitoneal injection and oral administration; for 15 days.
    Result: Inhibited the release of the inflammatory cytokine IL-6 and enhance antioxidant activity.
    Molecular Weight

    206.24

    Formula

    C8H18N2O4

    CAS No.
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    N[C@@H](CCCCN)C(O)=O.CC(O)=O

    Structure Classification
    Initial Source
    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage

    4°C, protect from light

    *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

    Solvent & Solubility
    In Vitro: 

    H2O : 116.67 mg/mL (565.70 mM; Need ultrasonic)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 4.8487 mL 24.2436 mL 48.4872 mL
    5 mM 0.9697 mL 4.8487 mL 9.6974 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • Molarity Calculator

    • Dilution Calculator

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    This equation is commonly abbreviated as: C1V1 = C2V2

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    In Vivo Dissolution Calculator
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    Calculation results:
    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    Purity & Documentation

    Purity: 98.0%

    References

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    H2O 1 mM 4.8487 mL 24.2436 mL 48.4872 mL 121.2180 mL
    5 mM 0.9697 mL 4.8487 mL 9.6974 mL 24.2436 mL
    10 mM 0.4849 mL 2.4244 mL 4.8487 mL 12.1218 mL
    15 mM 0.3232 mL 1.6162 mL 3.2325 mL 8.0812 mL
    20 mM 0.2424 mL 1.2122 mL 2.4244 mL 6.0609 mL
    25 mM 0.1939 mL 0.9697 mL 1.9395 mL 4.8487 mL
    30 mM 0.1616 mL 0.8081 mL 1.6162 mL 4.0406 mL
    40 mM 0.1212 mL 0.6061 mL 1.2122 mL 3.0304 mL
    50 mM 0.0970 mL 0.4849 mL 0.9697 mL 2.4244 mL
    60 mM 0.0808 mL 0.4041 mL 0.8081 mL 2.0203 mL
    80 mM 0.0606 mL 0.3030 mL 0.6061 mL 1.5152 mL
    100 mM 0.0485 mL 0.2424 mL 0.4849 mL 1.2122 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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    Product Name:
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