Recombinant Humanized Type III Collagen 28.6kDa

Cat. No.: HY-NP132 Purity: 95.00%: Data Sheet
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Recombinant Humanized Type III Collagen 28.6kDa is a 28.6 kDa recombinant humanized type III collagen. Recombinant Humanized Type III Collagen possesses a variety of biological functions, such as promoting the regeneration of the skin extracellular matrix and improving the cellular microenvironment. Recombinant Humanized Type III Collagen can also inhibit the proliferation, migration and invasion of breast cancer cells. Recombinant Humanized Type III Collagen plays a role in cell adhesion, migration, proliferation and differentiation by interacting with Integrin.

For research use only. We do not sell to patients.

Recombinant Humanized Type III Collagen 28.6kDa Chemical Structure

Size	Stock	Quantity
10 g	In-stock	Estimated Time of Arrival: December 31
50 g	In-stock	Estimated Time of Arrival: December 31
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•Related Small Molecules:

•Related Proteins:

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αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α9β1 αIIbβ3 α4β7 αLβ2

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DDR1 DDR2

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Description	Recombinant Humanized Type III Collagen 28.6kDa is a 28.6 kDa recombinant humanized type III collagen. Recombinant Humanized Type III Collagen possesses a variety of biological functions, such as promoting the regeneration of the skin extracellular matrix and improving the cellular microenvironment. Recombinant Humanized Type III Collagen can also inhibit the proliferation, migration and invasion of breast cancer cells. Recombinant Humanized Type III Collagen plays a role in cell adhesion, migration, proliferation and differentiation by interacting with Integrin^[1]^[2].
In Vitro	Recombinant Humanized Type III Collagen can significantly inhibit the proliferation, migration, invasion and autophagy of various breast cancer cells, induce cell apoptosis and dormancy, and is non-toxic to normal breast epithelial cells, and this effect depends on the DDR1 pathway^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Recombinant Humanized Type III Collagen 28.6kDa Related Antibodies
Appearance	Solid
Color	White to off-white
SMILES	[Recombinant Humanized Type III Collagen 28.6kDa]
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Purity: 95.00% Select Batch: Data Sheet (263 KB) SDS (251 KB) COA (232 KB) Handling Instructions (2659 KB)
References	[1]. Liu X, et al., Recombinant humanized collagen type III with high antitumor activity inhibits breast cancer cells autophagy, proliferation, and migration through DDR1. Int J Biol Macromol. 2023 Jul 15;243:125130. [Content Brief] [2]. Kuivaniemi H, et al. Type III collagen (COL3A1): Gene and protein structure, tissue distribution, and associated diseases. Gene. 2019 Jul 30;707:151-171. [Content Brief]