Recombinant Humanized Type III Collagen 28.6kDa 

Recombinant Humanized Type III Collagen 28.6kDa is a 28.6 kDa recombinant humanized type III collagen. Recombinant Humanized Type III Collagen possesses a variety of biological functions, such as promoting the regeneration of the skin extracellular matrix and improving the cellular microenvironment. Recombinant Humanized Type III Collagen can also inhibit the proliferation, migration and invasion of breast cancer cells. Recombinant Humanized Type III Collagen plays a role in cell adhesion, migration, proliferation and differentiation by interacting with Integrin^[1][2].

Recombinant Humanized Type III Collagen can significantly inhibit the proliferation, migration, invasion and autophagy of various breast cancer cells, induce cell apoptosis and dormancy, and is non-toxic to normal breast epithelial cells, and this effect depends on the DDR1 pathway^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Solid

White to off-white

[Recombinant Humanized Type III Collagen 28.6kDa]

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Liu X, et al., Recombinant humanized collagen type III with high antitumor activity inhibits breast cancer cells autophagy, proliferation, and migration through DDR1. Int J Biol Macromol. 2023 Jul 15;243:125130.  [Content Brief]

  [2]. Kuivaniemi H, et al. Type III collagen (COL3A1): Gene and protein structure, tissue distribution, and associated diseases. Gene. 2019 Jul 30;707:151-171.  [Content Brief]