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Als Inhibitors

" in MedChemExpress (MCE) Product Catalog:

29

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阻害性抗体

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同位体標識化合物

Targets Recommended:
製品番号 製品名 Target 研究分野 構造式
  • HY-12983
    ALS-8112
    2 Publications Verification

    		 RSV Infection
    ALS-8112 is a potent and selective respiratory syncytial virus (RSV) polymerase inhibitor. The 5'-triphosphate form of ALS-8112 inhibits RSV polymerase with an IC50 of 0.02 μM.
    ALS-8112
  • HY-12983A
    Lumicitabine
    1 Publications Verification

    Als-008176; Als-8176

    		 RSV Infection
    Lumicitabine (ALS-008176) is an inhibitor of the respiratory syncytial virus (RSV) polymerase.
    Lumicitabine
  • HY-B1847
    Terbuthylazine

    		Acetolactate Synthase (ALS) Others
    Terbuthylazine is an inhibitor of acetolactate syntase (ALS), is a selective herbicide.
    Terbuthylazine
  • HY-B1847S1
    Terbuthylazine-d5

    		Acetolactate Synthase (ALS) Others
    Terbuthylazine-d5 is the deuterium labeled Terbuthylazine[1]. Terbuthylazine is an inhibitor of acetolactate syntase (ALS), is a selective herbicide[2].
    Terbuthylazine-d5
  • HY-B1852
    Sulfometuron-methyl

    		Bacterial Fungal Infection
    Sulfometuron-methyl is a herbicide and also a powerful inhibitor of the enzyme acetolactate synthase (ALS). It exhibits antibacterial and antifungal activities, capable of inhibiting the activity of Salmonella. typhimurium ALS II and Escherichia. coli ALS III .
    Sulfometuron-methyl
  • HY-111032
    Allisartan isoproxil

    		Angiotensin Receptor Cardiovascular Disease
    Allisartan isoproxil (ALS-3) is an orally potent, selective, non-peptide inhibitor of Angiotensin II Type 1. Allisartan isoproxil is also an antihypertensive agent. Allisartan isoproxil may inhibit angiotensin-aldosterone system and oxidative stress. Allisartan isoproxil lowers blood pressure and protects the organs, preventing cerebrovascular damage. Allisartan isoproxil (80-320 mg/kg/d) has shown toxicity in rat models by targeting liver organs .
    Allisartan isoproxil
  • HY-B0869A
    Bispyribac sodium

    		Acetolactate Synthase (ALS) Others
    Bispyribac sodium is a selective, systemic and post emergent herbicide used to eradicate grasses and broad leaf weeds. Bispyribac sodium is also an acetolactate synthase (ALS or known as AHAS) inhibitor .
    Bispyribac sodium
  • HY-126987
    Mesosulfuron-methyl

    		Acetolactate Synthase (ALS) Others
    Mesosulfuron-methyl is a sulfonylurea herbicide that inhibits acetolactate synthase (ALS) and is used in research for post-emergence control of ryegrass and Avena spp. (wild oat) in wheat fields .
    Mesosulfuron-methyl
  • HY-125999
    EPI-589

    		Others Neurological Disease
    EPI-589, a quinone derivative, is a safe and well tolerated oxidoreductase enzyme inhibitor. EPI-589 has the potential for the treatment of amyotrophic lateral sclerosis (ALS) .
    EPI-589
  • HY-153019
    NUCC-0000323

    		SOD Neurological Disease
    NUCC-0000323 is a potent superoxide dismutase 1 (SOD1) inhibitor. NUCC-0000323 inhibits SOD1 expression. NUCC-0000323 can be used in research of amyotrophic lateral sclerosis (ALS) .
    NUCC-0000323
  • HY-B1876
    Nicosulfuron

    		Acetolactate Synthase (ALS) Others
    Nicosulfuron is a selective herbicide belonging to the sulfonylurea family. Nicosulfuron is commonly used as a post-emergence herbicide to protect maize crops from weeds. Nicosulfuron inhibits acetolactate synthase (ALS) enzyme activity .
    Nicosulfuron
  • HY-100427
    Imazamox

    CL29926; (±)-Imazamox

    		 Acetolactate Synthase (ALS) Others
    Imazamox (CL29926) is a systemic herbicide that inhibits the production of acetolactate synthase (ALS) in plants with high selectivity, high activity, safety and broadspectrum activity, which would then inhibit plant growth and ultimately lead to plant death .
    Imazamox
  • HY-W422402
    Foramsulfuron

    		Acetolactate Synthase (ALS) Others
    Foramsulfuron is a postemergence herbicide used for selective control of grass and some broadleaved weeds in maize (Zea mays L.). Foramsulfuron is a sulfonylurea herbicide that exerts its herbicidal activity by inhibiting acetolactate synthase (ALS), a key enzyme in the biosynthesis of branched chain amino acids .
    Foramsulfuron
  • HY-162303
    C175-0062

    		Monoamine Oxidase Neurological Disease
    C175-0062 is a monoamine oxidase B (MAO-B) inhibitor. C175-0062 can be used for the research of neurodegenerative disorders, including Parkinson's disease (PD), Alzheimer’s disease (AD), and amyotrophic lateral sclerosis (ALS) .
    C175-0062
  • HY-100427R
    Imazamox (Standard)

    CL29926 (Standard); (±)-Imazamox (Standard)

    		 Acetolactate Synthase (ALS) Others
    Imazamox (Standard) is the analytical standard of Imazamox. This product is intended for research and analytical applications. Imazamox (CL29926) is a systemic herbicide that inhibits the production of acetolactate synthase (ALS) in plants with high selectivity, high activity, safety and broadspectrum activity, which would then inhibit plant growth and ultimately lead to plant death .
    Imazamox (Standard)
  • HY-B1876S
    Nicosulfuron-d6

    		Acetolactate Synthase (ALS) Others
    Nicosulfuron-d6 is the deuterium labeled Nicosulfuron[1]. Nicosulfuron is a selective herbicide belonging to the sulfonylurea family. Nicosulfuron is commonly used as a post-emergence herbicide to protect maize crops from weeds. Nicosulfuron inhibits acetolactate synthase (ALS) enzyme activity[2].
    Nicosulfuron-d6
  • HY-B1876R
    Nicosulfuron (Standard)

    		Acetolactate Synthase (ALS) Others
    Nicosulfuron (Standard) is the analytical standard of Nicosulfuron. This product is intended for research and analytical applications. Nicosulfuron is a selective herbicide belonging to the sulfonylurea family. Nicosulfuron is commonly used as a post-emergence herbicide to protect maize crops from weeds. Nicosulfuron inhibits acetolactate synthase (ALS) enzyme activity .
    Nicosulfuron (Standard)
  • HY-N2707
    6-Deoxyjacareubin

    		Reactive Oxygen Species Neurological Disease Cancer
    6-Deoxyjacareubin is a natural xanthone, that can be isolated from the leaves of Vismia latifolia. 6-Deoxyjacareubin protects against non-apoptotic cell death by inhibiting ROS production. 6-Deoxyjacareubin ameliorates neurodegeneration in a mouse model of familial amyotrophic lateral sclerosis (ALS) .
    6-Deoxyjacareubin
  • HY-100427S
    Imazamox-13C,d3

    CL29926-13C,d3; (±)-Imazamox-13C,d3

    		 Acetolactate Synthase (ALS) Isotope-Labeled Compounds Others
    Imazamox- 13C,d3 is the 13C- and deuterium labeled Imazamox. Imazamox (CL29926) is a systemic herbicide that inhibits the production of acetolactate synthase (ALS) in plants with high selectivity, high activity, safety and broadspectrum activity, which would then inhibit plant growth and ultimately lead to plant death[1][2].
    Imazamox-13C,d3
  • HY-12768B
    Sotuletinib dihydrochloride

    BLZ945 dihydrochloride

    		 c-Fms Neurological Disease Cancer
    Sotuletinib (BLZ945) dihydrochloride is an orally active and blood-brain barrier-permeable CSF1-R-specific inhibitor (IC50=1 nM). Sotuletinib (BLZ945) dihydrochloride induces tumor cell apoptosis and effectively inhibits tumor growth in mouse models. Sotuletinib dihydrochloride can be used in cancer and amyotrophic lateral sclerosis (ALS) research .
    Sotuletinib dihydrochloride
  • HY-N11854
    Brassicanate A sulfoxide

    		Others Others
    Brassicanate A sulfoxide has herbicidal activity. Brassicanate A sulfoxide inhibits the biosynthesis of essential amino acids in plants. Brassicanate A sulfoxide binds to dihydroxyacid dehydratase (DHAD), hydroxymethylpyruvate dioxygenase (HPPD), acetolactate synthase (ALS), PYL family proteins and transport inhibitor response 1 (TIR1), and reduces their activity. Brassicanate A sulfoxide can be isolated from Brassica oleracea .
    Brassicanate A sulfoxide
  • HY-P3709
    TRAF6 peptide

    		p62 E1/E2/E3 Enzyme Neurological Disease
    TRAF6 peptide is a specific TRAF6-p62 inhibitor. TRAF6 peptide potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 peptide has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke .
    TRAF6 peptide
  • HY-P3709A
    TRAF6 peptide TFA

    		p62 E1/E2/E3 Enzyme Neurological Disease
    TRAF6 peptide TFA is a specific TRAF6-p62 inhibitor. TRAF6 peptide TFA potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 peptide TFA has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke .
    TRAF6 peptide TFA
  • HY-123982
    SOD1-Derlin-1 inhibitor-2

    		Others Neurological Disease
    SOD1-Derlin-1 inhibitor-2 (compound 56-59) is an inhibitor of SOD1-Derlin-1 interaction. SOD1-Derlin-1 inhibitor-2 attenuates the interactions between Derlin-1 and SOD1 mut. SOD1-Derlin-1 inhibitor-2 can be used for the research of amyotrophic lateral sclerosis (ALS) .
    SOD1-Derlin-1 <em>inhibitor</em>-2
  • HY-144425
    BSc5367

    		Others Inflammation/Immunology
    BSc5367 is a potent Nek1 inhibitor with an IC50 of 11.5 nM. NIMA-related protein kinase Nek1 is crucially involved in cell cycle regulation, DNA repair and microtubule regulation and dysfunctions of Nek1 play key roles in amyotrophic lateral sclerosis (ALS), polycystic kidney disease (PKD) and several types of radiotherapy resistant cancer .
    BSc5367
  • HY-146530
    c-ABL-IN-4

    		Others Neurological Disease Cancer
    c-ABL-IN-4 is a potent inhibitor of c-Abl. Activation of c-Abl has been implicated in various diseases, notably cancer. c-ABL-IN-4 has the potential for the research of neurodegenerative diseases (amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD) and cancer (extracted from patent WO2021048567A1, compound 54) .
    c-ABL-IN-4
  • HY-146528
    c-ABL-IN-3

    		Others Neurological Disease Cancer
    c-ABL-IN-3 is a potent inhibitor of c-Abl. Activation of c-Abl has been implicated in various diseases, notably cancer. c-ABL-IN-3 has the potential for the research of neurodegenerative diseases (amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD) and cancer (extracted from patent WO2021048567A1, compound 50) .
    c-ABL-IN-3
  • HY-145294
    ROCK2-IN-5

    		ROCK Neurological Disease
    ROCK2-IN-5 (compound 1d) is a hybrid compound containing structural fragments of the Rho kinase inhibitor fasudil and the NRF2 inducers caffeic and ferulic acids. ROCK2-IN-5 has good multitarget profile and good tolerability. ROCK2-IN-5 has the potential for thr research of Amyotrophic lateral sclerosis (ALS) with a SOD1 mutation .
    ROCK2-IN-5
  • HY-146527
    c-ABL-IN-2

    		Bcr-Abl Neurological Disease Cancer
    c-ABL-IN-2 is a potent inhibitor of c-Abl. Activation of c-Abl has been implicated in various diseases, notably cancer. c-ABL-IN-2 has the potential for the research of neurodegenerative diseases (amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD) and cancer (extracted from patent WO2020260871A1, compound 25) . c-ABL-IN-2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    c-ABL-IN-2

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