1. Autophagy Metabolic Enzyme/Protease
  2. p62 E1/E2/E3 Enzyme
  3. TRAF6 peptide

TRAF6 peptide is a specific TRAF6-p62 inhibitor. TRAF6 peptide potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 peptide has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke.

For research use only. We do not sell to patients.

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TRAF6 peptide Chemical Structure

TRAF6 peptide Chemical Structure

CAS No. : 852805-92-6

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Description

TRAF6 peptide is a specific TRAF6-p62 inhibitor. TRAF6 peptide potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 peptide has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke[1].

In Vitro

TRAF6 peptide (150 µM; 5 h) blocks the interaction of p62 with TRAF6 in PC12 cells[1].
TRAF6 peptide eliminates TRAF6 and UbcH7 from interacting with TrkA and can ffectively abolish NGF-dependent ubiquitination of TrkA in vitro[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis[1]

Cell Line: PC12 cells
Concentration: 150 µM
Incubation Time: 5 h
Result: Inhibited the interaction of p62 with TRAF6 by immunoprecipitating TRA F6.
Molecular Weight

3161.64

Formula

C145H238N34O44

CAS No.
Sequence Shortening

AAVALLPAVLLALLAPESASGPSEDPSVNFLK

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TRAF6 peptide Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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TRAF6 peptide
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HY-P3709
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