TRAF6 peptide
TRAF6 peptide is a specific TRAF6-p62 inhibitor. TRAF6 peptide potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 peptide has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke.
For research use only. We do not sell to patients.
- CAS No.: 852805-92-6
- Formula: C145H238N34O44
- Molecular Weight:3161.64
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
TRAF6 peptide (150 µM; 5 h) blocks the interaction of p62 with TRAF6 in PC12 cells[1].
TRAF6 peptide eliminates TRAF6 and UbcH7 from interacting with TrkA and can ffectively abolish NGF-dependent ubiquitination of TrkA in vitro[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:PC12 cells
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Concentration:150 µM
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Incubation Time:5 h
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Result:Inhibited the interaction of p62 with TRAF6 by immunoprecipitating TRA F6.
Chemical Information
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CAS No. 852805-92-6
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Molecular Weight 3161.64
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Formula C145H238N34O44
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Sequence Shortening
AAVALLPAVLLALLAPESASGPSEDPSVNFLK
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)