Imazamox-13C,d3
Based on 1 Customer Validation
Imazamox-13C,d3 is the 13C- and deuterium labeled Imazamox. Imazamox (CL29926) is a systemic herbicide that inhibits the production of acetolactate synthase (ALS) in plants with high selectivity, high activity, safety and broadspectrum activity, which would then inhibit plant growth and ultimately lead to plant death.
For research use only. We do not sell to patients.
- Purity: 99.63%
- Formula: C1413CH16D3N3O4
- Molecular Weight:309.34
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[91].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 114311-32-9
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Appearance Solid
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Molecular Weight 309.34
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Formula C1413CH16D3N3O4
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Color White to off-white
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SMILES
O=C(O)C1=C(C2=NC(C)(C(C)C)C(N2)=O)N=CC(CO[13C]([2H])([2H])[2H])=C1
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Synonyms
CL29926-13C,d3; (±)-Imazamox-13C,d3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 20 mg/mL (64.65 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]
[2]. García-Garijo A, et al. Metabolic responses in root nodules of Phaseolus vulgaris and Vicia sativa exposed to the imazamox herbicide. Pestic Biochem Physiol. 2014 May;111:19-23. [Content Brief]
[3]. Wei J et al. Enantioselective Phytotoxicity of Imazamox Against Maize Seedlings. Bull Environ Contam Toxicol. 2016 Feb;96(2):242-7. [Content Brief]
[4]. Imazamox Chemical Fact Sheet. Wisconsin Department of Natural Resources. DNR PUB-WT-974 2012.
[5]. Sevim Ç, et al. An imazamox-based herbicide causes apoptotic changes in rat liver and pancreas. Toxicol Rep. 2018 Nov 19;6:42-50. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 3.2327 mL | 16.1634 mL | 32.3269 mL | 80.8172 mL |
| 5 mM | 0.6465 mL | 3.2327 mL | 6.4654 mL | 16.1634 mL | |
| 10 mM | 0.3233 mL | 1.6163 mL | 3.2327 mL | 8.0817 mL | |
| 15 mM | 0.2155 mL | 1.0776 mL | 2.1551 mL | 5.3878 mL | |
| 20 mM | 0.1616 mL | 0.8082 mL | 1.6163 mL | 4.0409 mL | |
| 25 mM | 0.1293 mL | 0.6465 mL | 1.2931 mL | 3.2327 mL | |
| 30 mM | 0.1078 mL | 0.5388 mL | 1.0776 mL | 2.6939 mL | |
| 40 mM | 0.0808 mL | 0.4041 mL | 0.8082 mL | 2.0204 mL | |
| 50 mM | 0.0647 mL | 0.3233 mL | 0.6465 mL | 1.6163 mL | |
| 60 mM | 0.0539 mL | 0.2694 mL | 0.5388 mL | 1.3470 mL |
Imazamox-13C,d3 Related Classifications
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