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Imazamox (Synonyms: CL29926; (±)-Imazamox)

Cat. No.: HY-100427 Purity: 99.69%
Handling Instructions

Imazamox (CL29926) is a systemic herbicide that inhibits the production of acetolactate synthase (ALS) in plants with high selectivity, high activity, safety and broadspectrum activity, which would then inhibit plant growth and ultimately lead to plant death.

For research use only. We do not sell to patients.

Imazamox Chemical Structure

Imazamox Chemical Structure

CAS No. : 114311-32-9

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Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
10 mg USD 60 In-stock
Estimated Time of Arrival: December 31
50 mg USD 84 In-stock
Estimated Time of Arrival: December 31
100 mg USD 108 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Imazamox (CL29926) is a systemic herbicide that inhibits the production of acetolactate synthase (ALS) in plants with high selectivity, high activity, safety and broadspectrum activity, which would then inhibit plant growth and ultimately lead to plant death[1][2].

In Vitro

Half-life of Imazamox in the soil ranges from 1 to 3 months exhibit low mammalian toxicity[1]. Plants are treated with Imazamox (250 μM) in the nutrient solution and harvested 7 days after. Imazamox is mainly accumulated in V. sativa, six fold higher than those detected in P.vulgaris[3].

In Vivo

Imazamox (12-36 mg/kg; intraperitoneal injection; for 24-72 hours; male Sprague-Dawley rats) treatment induces toxic effects in the liver and pancreas of Sprague Dawley rats. Necrotic and degenerative changes are detected in hepatocytes at the two highest doses. Imazamox treatment reduces the size of the β-islet cells, and also induces an elevation in serum glucose and calcium[4].

Animal Model: 50 male Sprague-Dawley rats (300 ± 10 g)[3]
Dosage: 12 mg/kg, 24 mg/kg and 36 mg/kg
Administration: Intraperitoneal injection; for 24 hours, 48 hours or 72 hours
Result: Induced toxic effects in the liver and pancreas.
Molecular Weight

305.33

Formula

C₁₅H₁₉N₃O₄

CAS No.

114311-32-9

SMILES

O=C(C1=CC(COC)=CN=C1C(NC2(C)C(C)C)=NC2=O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 20 mg/mL (65.50 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2751 mL 16.3757 mL 32.7515 mL
5 mM 0.6550 mL 3.2751 mL 6.5503 mL
10 mM 0.3275 mL 1.6376 mL 3.2751 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2 mg/mL (6.55 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2 mg/mL (6.55 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2 mg/mL (6.55 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 99.69%

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Keywords:

ImazamoxCL29926(±)-ImazamoxCL 29926CL-29926OthersInhibitorinhibitorinhibit

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Product name:
Imazamox
Cat. No.:
HY-100427
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