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Results for "

Flame Retardant

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (2) Apoptosis (8) Biochemical Assay Reagents (37) Calcium Channel (2) Cholinesterase (ChE) (1) ClpP (1) Cytochrome P450 (3) DNA Alkylator/Crosslinker (2) DNA/RNA Synthesis (4) Drug Metabolite (3) Endogenous Metabolite (2) Environmental Pollutants (6) ERK (2) Estrogen Receptor/ERR (1) Eukaryotic Initiation Factor (eIF) (1) FXR (2) HSP (1) Indoleamine 2,3-Dioxygenase (IDO) (2) Insecticide (1) Interleukin Related (3) Isotope-Labeled Compounds (5) JNK (2) LDLR (1) MDM-2/p53 (1) Mitochondrial Metabolism (2) Mitophagy (2) Monoamine Oxidase (2) NF-κB (4) p38 MAPK (2) PI3K (2) PPAR (3) Progesterone Receptor (1) Reactive Oxygen Species (ROS) (5) Reference Standards (2) SOD (2) TGF-beta/Smad (1) TNF Receptor (3) Toll-like Receptor (TLR) (2)
By Research Areas:	Cancer (7) Cardiovascular Disease (3) Endocrinology (5) Infection (1) Inflammation/Immunology (5) Metabolic Disease (7) Neurological Disease (5)

By Targets:

Akt (2)

Apoptosis (8)

Biochemical Assay Reagents (37)

Calcium Channel (2)

Cholinesterase (ChE) (1)

ClpP (1)

Cytochrome P450 (3)

DNA Alkylator/Crosslinker (2)

DNA/RNA Synthesis (4)

Drug Metabolite (3)

Endogenous Metabolite (2)

Environmental Pollutants (6)

ERK (2)

Estrogen Receptor/ERR (1)

Eukaryotic Initiation Factor (eIF) (1)

FXR (2)

HSP (1)

Indoleamine 2,3-Dioxygenase (IDO) (2)

Insecticide (1)

Interleukin Related (3)

Isotope-Labeled Compounds (5)

JNK (2)

LDLR (1)

MDM-2/p53 (1)

Mitochondrial Metabolism (2)

Mitophagy (2)

Monoamine Oxidase (2)

NF-κB (4)

p38 MAPK (2)

PI3K (2)

PPAR (3)

Progesterone Receptor (1)

Reactive Oxygen Species (ROS) (5)

Reference Standards (2)

SOD (2)

TGF-beta/Smad (1)

TNF Receptor (3)

Toll-like Receptor (TLR) (2)

By Research Areas:

Cancer (7)

Cardiovascular Disease (3)

Endocrinology (5)

Infection (1)

Inflammation/Immunology (5)

Metabolic Disease (7)

Neurological Disease (5)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-107859

Tris(2-chloroethyl) phosphate 5+ Cited Publications TCEP	Environmental Pollutants Apoptosis FXR Calcium Channel Toll-like Receptor (TLR) SOD Reactive Oxygen Species (ROS) DNA/RNA Synthesis Interleukin Related NF-κB TNF Receptor	Others
Tris(2-chloroethyl) phosphate (TCEP) is a widely used organic phosphorus flame retardant, mainly used as a plasticizer. Tris(2-chloroethyl) phosphate has orally active hepatotoxicity, inducing an increase in reactive oxygen species (ROS) and calcium ions (Ca²⁺) influx, a decrease in mitochondrial membrane potential (△Ψm), and causing DNA damage and cell apoptosis. Tris(2-chloroethyl) phosphate directly binds to FXR, inducing obesity and the formation of fatty liver in mice. Chloroethyl) phosphate activates the TLR4/NF-κB pathway, triggering liver inflammation .

HY-W018587

TBPH	Mitochondrial Metabolism Cytochrome P450 TNF Receptor Interleukin Related HSP LDLR Eukaryotic Initiation Factor (eIF) ClpP	Metabolic Disease Inflammation/Immunology
TBPH is a brominated flame retardant. TBPH enhances hepatic steatosis, inflammation, and fibrosis in mice with nonalcoholic steatohepatitis (NASH). TBPH induces dysregulation of phospholipid metabolism, reducing cardiolipin (CL) and phosphatidylserine (PS) levels. TBPH leads to impaired endoplasmic reticulum-mitochondria (ER-Mito) contacts, subsequently causing mitochondrial dysfunction. TBPH induces lung injury through an inflammatory response mediated by mitochondria-derived ds-DNA. TBPH can be used to study the role of MFN2-mediated ER-mitochondria contacts in lipid metabolism homeostasis .

HY-108712

TDCPP Maximum Cited Publications 8 Publications Verification Tris(1,3-dichloroisopropyl)phosphate	Biochemical Assay Reagents	Cancer
TDCPP is a chlorinated analog of tris(2,3-dibromopropyl)phosphate (Tris) which is one of the most detected organophosphorus flame retardants (OPFRs) in the environment.

HY-15929

TBHBA 1 Publications Verification 2,4,6-Tribromo-3-hydroxybenzoic acid	Biochemical Assay Reagents	Others
TBHBA (2,4,6-Tribromo-3-hydroxybenzoic acid) is a chemical colorimetric agent and nanomaterial surface modifier. TBHBA can react with some oxidants (such as H₂O₂) to generate high-absorbance quinoneimine dyes, which enhance the sensitivity of HDL cholesterol enzymatic determination. TBHBA can be used as a bromine-containing coupling agent to modify the surface of silica nanoparticles through esterification reaction. Thereby, organic flame retardant groups are introduced to improve the thermal stability and flame retardant properties of nanocomposites. TBHBA can be used in clinical biochemical testing (such as serum lipoprotein analysis) and the preparation of flame-retardant polymer nanocomposites .

HY-Y1322

Triphenyl phosphate	Environmental Pollutants Mitophagy Apoptosis NF-κB p38 MAPK ERK JNK PI3K Akt Monoamine Oxidase Reactive Oxygen Species (ROS) PPAR Indoleamine 2,3-Dioxygenase (IDO)	Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Endocrinology
Triphenyl phosphate is an orally active, blood-brain barrier-permeable aryl organophosphate flame retardant and endocrine disruptor. Triphenyl phosphate disrupts mitochondrial dynamic balance through oxidative stress, induces excessive mitophagy and apoptosis, and ultimately leads to myocardial fibrosis. In the brain, Triphenyl phosphate activates the NF-κB inflammatory pathway by disrupting the gut microbiota, alters tryptophan metabolism and elevates neurotoxins, thereby inducing anxiety- and depression-like behaviors. In the skeletal and reproductive systems, Triphenyl phosphate inhibits osteoblast differentiation and induces germ cell apoptosis by suppressing the MAPK/ERK pathway and activating the JNK signal, respectively. In adipose and placental tissues, Triphenyl phosphate promotes lipid accumulation by activating the PI3K/AKT-PPARγ axis, and disrupts placental metabolism via the MAOA/ROS/NF-κB cascade, impairing neurodevelopment of offspring .

HY-W399311

4-Hydroxyphenyl diphenyl phosphate	Drug Metabolite	Others
4-Hydroxyphenyl diphenyl phosphate is a hydroxylated metabolite of organophosphate flame retardant .

HY-W013058

Decabromodiphenyl ethane DBDPE; 1,2-Bis(perbromophenyl)ethane	Biochemical Assay Reagents	Neurological Disease Metabolic Disease
Decabromodiphenyl ethane (DBDPE; 1,2-Bis(perbromophenyl)ethane) is a brominated flame retardant. Decabromodiphenyl ethane can exhibit neurotoxicity, thyroid toxicity, reproductive developmental toxicity, hepatotoxicity, and oxidative stress in living organisms .

HY-Y1155

Hexamethylphosphoramide HMPA	Environmental Pollutants DNA Alkylator/Crosslinker Biochemical Assay Reagents Cytochrome P450	Inflammation/Immunology Endocrinology Cancer
Hexamethylphosphoramide is an orally active polar aprotic solvent, flame retardant additive, and carcinogen. Hexamethylphosphoramide undergoes cytochrome P-450-mediated N-demethylation to Formaldehyde. Hexamethylphosphoramide induces DNA-protein crosslinks. Hexamethylphosphoramide has been linked to nasal tumors (squamous cell carcinoma, adenoid squamous cell carcinoma), squamous metaplasia, rhinitis, tracheitis, and reversible and irreversible infertility .

HY-W009066

2-Ethylhexyl diphenyl phosphate EHDPP; Octicizer	PPAR Progesterone Receptor Estrogen Receptor/ERR	Endocrinology
2-Ethylhexyl diphenyl phosphate is an organophosphate flame retardants (OPFRs) and a PPARG agonist (EC₂₀: 2.04 µM). 2-Ethylhexyl diphenyl phosphate also inhibits ERRγ transcriptional activity (IC₅₀: 1.3 µM). 2-Ethylhexyl diphenyl phosphate upregulates 3β-HSD1, human chorionic gonadotropin (hCG) and progesterone secretion. 2-Ethylhexyl diphenyl phosphate can be used in studies of female reproduction and fetal development .

HY-W008954

Tris(2-ethylhexyl) phosphate	Environmental Pollutants Biochemical Assay Reagents	Others
Tris(2-ethylhexyl) phosphate is an organophosphorus flame retardant analog with considerable ecological toxicity. Tris(2-ethylhexyl) phosphate can be used as neutral carriers to make organic ammonium ion-selective membrane electrodes. Tris(2-ethylhexyl) phosphate is widely applied in furniture, textiles, building materials, electronics, and other chemicals .

HY-W105318

Pentabromophenol PBP	TGF-beta/Smad Apoptosis	Cancer
Pentabromophenol (PBP) is a brominated flame retardant (BFR) widely used in various consumer products to reduce the flammability of materials used in different utility items. Pentabromophenol can accelerate the degradation of transforming growth factor-β (TGF-β) receptors by promoting clathrin-mediated endocytosis, thereby inhibiting the TGF-β signaling pathway. Additionally, Pentabromophenol can also induce apoptosis in peripheral blood mononuclear cells (PBMCs) .

HY-W023144

Tris(1-chloro-2-propyl) phosphate Tris(1-chloropropan-2-yl) phosphate	Environmental Pollutants Apoptosis DNA/RNA Synthesis Reactive Oxygen Species (ROS) Mitochondrial Metabolism Biochemical Assay Reagents	Cardiovascular Disease
Tris (1-chloro-2-propyl) phosphate (Tris (1-chloropropan-2-yl) phosphate) is a chlorinated organophosphate flame retardant. Tris (1-chloro-2-propyl) phosphate induces DNA damage, elevates intracellular ROS levels, and triggers oxidative stress. Tris (1-chloro-2-propyl) phosphate disrupts mitochondrial membrane potential, leading to mitochondrial dysfunction. Tris (1-chloro-2-propyl) phosphate can trigger cell Apoptosis. Tris (1-chloro-2-propyl) phosphate reduces the survival rate of umbilical vein endothelial cells at relatively high concentrations .

HY-Y1219E

Silica gel, high-purity grade, 130-270 mesh	Biochemical Assay Reagents	Others
Silica gel, high-purity grade, 130-270 mesh is a low-density, high-surface-area, high-purity inert additive that can be used to prepare chromatographic column sieve plates based on the sol-gel method. Silica gel, high-purity grade prevents DNA degradation by absorbing water from plant leaves, and is suitable for the preservation of field-collected samples for subsequent DNA extraction, restriction endonuclease digestion, PCR amplification and gene sequencing. It can also be reused after being saturated with water. Silica gel, high-purity grade can provide a non-toxic, inert aquatic environment for embedded cells, allowing nutrients, oxygen and metabolic waste to diffuse freely and blocking external pollution, thereby maintaining the activity of fibroblasts and epithelial cells .

HY-W019994

Tri-(p-tert-butylphenyl) phosphate	Biochemical Assay Reagents	Others
Tri-(p-tert-butylphenyl) phosphate is a flame retardant.

HY-W337886

2-Ethylhexyl 2,3,4,5-tetrabromobenzoate	Biochemical Assay Reagents	Others
2-Ethylhexyl 2,3,4,5-tetrabromobenzoate is a flame retardant .

HY-W585872

Bis(2-butoxyethyl) phosphate BBOEP	Biochemical Assay Reagents	Others
Bis(2-butoxyethyl) phosphate (BBOEP) is a metabolite of the flame retardant tris(2-butoxyethyl) phosphate (TBOEP). Bis(2-butoxyethyl) phosphate (BBOEP) can be used in biomonitoring studies and risk assessments .

HY-W718423

Isodecyl diphenyl phosphate IDPP	DNA/RNA Synthesis MDM-2/p53	Cancer
Isodecyl diphenyl phosphate (IDPP) is a flame retardant. Isodecyl diphenyl phosphate induces cytotoxicity, DNA damage, mitochondrial dysfunction and oxidative stress in cancer cells, and mediates DNA damage and cell cycle arrest via a p53-dependent pathway .

HY-W585826

Antiblaze 100 Antiblaze V6	Biochemical Assay Reagents	Others
Antiblaze 100 (Antiblaze V6) is a halogenated organophosphate flame retardant .

HY-W587835

Tris(3-chloropropyl) phosphate	Biochemical Assay Reagents	Others
Tris(3-chloropropyl) phosphate is a flame retardant.

HY-W549227

Butyl diphenyl phosphate	Biochemical Assay Reagents	Others
Butyl diphenyl phosphate is mainly used as a flame retardant and a plastic additive .

HY-W185336

Dibutyl phenyl phosphate	Cholinesterase (ChE)	Neurological Disease
Dibutyl phenyl phosphate is a flame retardant. Dibutyl phenyl phosphate is a BChE inhibitor (IC₅₀: 83.6 μM; K_i: 94.5 μM) .

HY-W392122

1,3-Phenylene tetraphenyl bisphosphate Tetraphenyl resorcinol bisdiphenylphosphate	Biochemical Assay Reagents	Others
1,3-Phenylene tetraphenyl bis(phosphate) (Tetraphenyl resorcinol bis(diphenylphosphate)) is a flame retardant.

HY-W292950

2-Biphenylyl phenyl phosphate o-Phenylphenyl bisphenyl phosphate	Biochemical Assay Reagents	Others
2-Biphenylyl phenyl phosphate (o-Phenylphenyl bisphenyl phosphate) is mainly used as a flame retardant and a plastic additive.

HY-W877743

4-(tert-Butyl)phenyl diphenyl phosphate p-t-Butylphenyl diphenyl phosphate	Biochemical Assay Reagents	Others
4-(tert-Butyl)phenyl diphenyl phosphate (p-t-Butylphenyl diphenyl phosphate) is mainly used as a flame retardant and lubricant.

HY-108712R

TDCPP (Standard) Tris(1,3-dichloroisopropyl)phosphate (Standard)	Biochemical Assay Reagents Reference Standards	Cancer
TDCPP (Standard) is the analytical standard of TDCPP. This product is intended for research and analytical applications. TDCPP is a chlorinated analog of tris(2,3-dibromopropyl)phosphate (Tris) which is one of the most detected organophosphorus flame retardants (OPFRs) in the environment.

HY-W585831

Bis(1,3-dichloro-2-propyl) phosphate BDCPP	Biochemical Assay Reagents	Others
Bis(1,3-dichloro-2-propyl) phosphate (BDCPP) is a metabolite of the flame retardant TDCPP (HY-108712) and has endocrine disrupting properties. Bis(1,3-dichloro-2-propyl) phosphate can be used in environmental monitoring, toxicology, and exposure assessment studies .

HY-W592622

Polyacrylonitrile (MW 250000)	Biochemical Assay Reagents	Others
Polyacrylonitrile is a fiber. Polyacrylonitrile is widely used as a material for the preparation of ultrafiltration membranes, hemodialysis membranes, textiles, flame retardants and carbon fibers. Polyacrylonitrile (MW 250000) can be electrospun .

HY-107859S

Tris(2-chloroethyl)phosphate-d12 TCEP-d₁₂	Isotope-Labeled Compounds Reactive Oxygen Species (ROS) Apoptosis DNA/RNA Synthesis Calcium Channel FXR Toll-like Receptor (TLR) NF-κB SOD Interleukin Related TNF Receptor	Others
Tris(2-chloroethyl)phosphate-d₁₂ is the deuterium labeled Tris(β-chloroethyl) phosphate. Tris(2-chloroethyl) phosphate is a widely used organic phosphorus flame retardant, mainly used as a plasticizer. Tris(2-chloroethyl) phosphate has orally active hepatotoxicity, inducing an increase in reactive oxygen species (ROS) and calcium ions (Ca²⁺) influx, a decrease in mitochondrial membrane potential (△Ψm), and causing DNA damage and cell apoptosis. Tris(2-chloroethyl) phosphate directly binds to FXR, inducing obesity and the formation of fatty liver in mice. Chloroethyl) phosphate activates the TLR4/NF-κB pathway, triggering liver inflammation.

HY-Y1322S

Triphenyl phosphate-d15 Celluflex TPP-d₁₅; DHPF 005-d₁₅; Disflamol TP-d₁₅; Disflamoll TP-d₁₅; NSC 57868-d₁₅; Phenyl phosphate ((PhO)3PO)-d₁₅; Phoscon FR 903N-d₁₅	Isotope-Labeled Compounds Environmental Pollutants ERK Indoleamine 2,3-Dioxygenase (IDO) p38 MAPK NF-κB Akt Monoamine Oxidase Mitophagy Reactive Oxygen Species (ROS) JNK PI3K PPAR Apoptosis	Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Endocrinology
Triphenyl phosphate-d₁₅ is the deuterium labeled Triphenyl phosphate. Triphenyl phosphate is an orally active, blood-brain barrier-permeable aryl organophosphate flame retardant and endocrine disruptor. Triphenyl phosphate disrupts mitochondrial dynamic balance through oxidative stress, induces excessive mitophagy and apoptosis, and ultimately leads to myocardial fibrosis. In the brain, Triphenyl phosphate activates the NF-κB inflammatory pathway by disrupting the gut microbiota, alters tryptophan metabolism and elevates neurotoxins, thereby inducing anxiety- and depression-like behaviors. In the skeletal and reproductive systems, Triphenyl phosphate inhibits osteoblast differentiation and induces germ cell apoptosis by suppressing the MAPK/ERK pathway and activating the JNK signal, respectively. In adipose and placental tissues, Triphenyl phosphate promotes lipid accumulation by activating the PI3K/AKT-PPARγ axis, and disrupts placental metabolism via the MAOA/ROS/NF-κB cascade, impairing neurodevelopment of offspring.

HY-W585928

Di-o-cresyl phosphate	Drug Metabolite	Others
Di-o-cresyl phosphate is a flame retardant.

HY-W587553

Di-p-Tolyl phosphate	Biochemical Assay Reagents	Others
Di-p-Tolyl phosphate is a flame retardant.

HY-W715244

Tris(3-isopropylphenyl) phosphate	Biochemical Assay Reagents	Others
Tris(3-isopropylphenyl) phosphate is a flame retardant.

HY-W585821

Bis(2,3-dibromopropyl) hydrogen phosphate	Biochemical Assay Reagents	Others
Bis(2,3-dibromopropyl) hydrogen phosphate is a flame retardant.

HY-W722114

5-HO-Ehdpp 5-OH-EHDPP	Drug Metabolite	Others
5-HO-Ehdpp (5-OH-EHDPP) is a flame retardant.

HY-127074

Chlorendic acid HET acid	Biochemical Assay Reagents	Others
Chlorendic acid (HET acid) can be used as a diacid component for the synthesis of oligoesters with potential flame retardant properties with aliphatic diols. Degradation by chlorine radicals may be responsible for the flame retardancy of HET acid-based oligoesters .

HY-W129561

Bisphenol A bisdiphenyl phosphate	Biochemical Assay Reagents	Others
Bisphenol A bis(diphenyl phosphate) is a flame retardant. Bisphenol A bis(diphenyl phosphate) shows a crucial condensed phase action in addition to a gas phase action .

HY-W200537

Propan-2-yl 2-sulfanylacetate Isopropyl thioglycolate	Biochemical Assay Reagents	Others
Propan-2-yl 2-sulfanylacetate (Isopropyl thioglycolate) can be used as a stabilizer for dyes, an additive for flame retardants, and a component in metal cleaning agents, etc .

HY-N2296

(2R,3R)-3,7-Dihydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-en-1-yl)chroman-4-one	Others	Others
(2R,3R)-3,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone can be used in a flame retardant for transparent polycarbonate products or in elevator illumination devices research .

HY-W288480

Trihexyl phosphate	Apoptosis	Cancer
Trihexyl phosphate is an organophosphate flame retardant. Trihexyl phosphate causes mitochondrial impairment and induces cell apoptosis in CHO cells. Trihexyl phosphate promotes the proliferation of human breast cancer cells (MCF-7) in a dose-dependent manner and exerts estrogenicity via ERα-independent pathways .

HY-141728

Bis(1-chloro-2-propyl) phosphate BCIPP	Endogenous Metabolite	Metabolic Disease
Bis(1-chloro-2-propyl) phosphate (BCIPP) is a metabolite of organophosphate flame retardants (OPFR) that may alter energy metabolism by influencing the levels of steroid hormones, such as cortisol and cortisone. Bis(1-chloro-2-propyl) phosphate holds potential for research on metabolism-related diseases caused by environmental exposure .

HY-W585884

Diisobutyl hydrogen phosphate	Biochemical Assay Reagents	Others
Diisobutyl hydrogen phosphate is a flame retardant.

HY-W877663

3-Isopropylphenyl diphenyl phosphate	Biochemical Assay Reagents	Others
3-Isopropylphenyl diphenyl phosphate is a flame retardant.

HY-W588267

2-(1-Methylethyl)phenyl diphenyl phosphate	Biochemical Assay Reagents	Others
2-(1-Methylethyl)phenyl diphenyl phosphate is a flame retardant.

HY-W588268

4-(1-Methylethyl)phenyl diphenyl phosphate	Biochemical Assay Reagents	Others
4-(1-Methylethyl)phenyl diphenyl phosphate is a flame retardant.

HY-W703900

Bis(2-isopropylphenyl) phenyl phosphate	Biochemical Assay Reagents	Others
Bis(2-isopropylphenyl) phenyl phosphate is a flame retardant.

HY-W585980

Bis(2-butoxyethyl) 2-hydroxyethyl phosphate	Biochemical Assay Reagents	Others
Bis(2-butoxyethyl) 2-hydroxyethyl phosphate is a flame retardant.

HY-W722110

4-HO-DPHP	Biochemical Assay Reagents	Others
4-HO-DPHP is a urinary metabolite of organophosphate flame retardants and plasticizer (OPFR) .

HY-W722115

5-HO-Ehdpp-d10	Isotope-Labeled Compounds	Others
5-HO-Ehdpp-d₁₀ is the deuterium labeled 5-HO-Ehdpp (HY-W722114). 5-HO-Ehdpp (5-OH-EHDPP) is a flame retardant.

HY-W040186

1-Naphthenyl phosphate hydrate sodium	Biochemical Assay Reagents	Others
1-Naphthenyl phosphate hydrate sodium is commonly used as a flame retardant for various materials such as plastics, textiles, and construction materials. In addition, its potential use as a corrosion inhibitor and as an ingredient in fertilizers and detergents has been investigated. Its hydrated form contains variable amounts of water molecules, which affects its physical properties and applications.

HY-Y1155S

Hexamethylphosphoramide-d18	Isotope-Labeled Compounds Biochemical Assay Reagents Cytochrome P450 DNA Alkylator/Crosslinker	Inflammation/Immunology Endocrinology Cancer
Hexamethylphosphoramide-d₁₈ is the deuterium labeled Hexamethylphosphoramide (HY-Y1155). Hexamethylphosphoramide is an orally active polar aprotic solvent, flame retardant additive, and carcinogen. Hexamethylphosphoramide undergoes cytochrome P-450-mediated N-demethylation to Formaldehyde. Hexamethylphosphoramide induces DNA-protein crosslinks. Hexamethylphosphoramide has been linked to nasal tumors (squamous cell carcinoma, adenoid squamous cell carcinoma), squamous metaplasia, rhinitis, tracheitis, and reversible and irreversible infertility .

Cat. No.	Product Name	Type

HY-15929

TBHBA

1 Publications Verification

2,4,6-Tribromo-3-hydroxybenzoic acid

Biochemical Assay Reagents

TBHBA (2,4,6-Tribromo-3-hydroxybenzoic acid) is a chemical colorimetric agent and nanomaterial surface modifier. TBHBA can react with some oxidants (such as H₂O₂) to generate high-absorbance quinoneimine dyes, which enhance the sensitivity of HDL cholesterol enzymatic determination. TBHBA can be used as a bromine-containing coupling agent to modify the surface of silica nanoparticles through esterification reaction. Thereby, organic flame retardant groups are introduced to improve the thermal stability and flame retardant properties of nanocomposites. TBHBA can be used in clinical biochemical testing (such as serum lipoprotein analysis) and the preparation of flame-retardant polymer nanocomposites .

HY-Y1155

Hexamethylphosphoramide

HMPA

Biochemical Assay Reagents

Hexamethylphosphoramide is an orally active polar aprotic solvent, flame retardant additive, and carcinogen. Hexamethylphosphoramide undergoes cytochrome P-450-mediated N-demethylation to Formaldehyde. Hexamethylphosphoramide induces DNA-protein crosslinks. Hexamethylphosphoramide has been linked to nasal tumors (squamous cell carcinoma, adenoid squamous cell carcinoma), squamous metaplasia, rhinitis, tracheitis, and reversible and irreversible infertility .

HY-Y1219E

Silica gel, high-purity grade, 130-270 mesh

Biochemical Assay Reagents

Silica gel, high-purity grade, 130-270 mesh is a low-density, high-surface-area, high-purity inert additive that can be used to prepare chromatographic column sieve plates based on the sol-gel method. Silica gel, high-purity grade prevents DNA degradation by absorbing water from plant leaves, and is suitable for the preservation of field-collected samples for subsequent DNA extraction, restriction endonuclease digestion, PCR amplification and gene sequencing. It can also be reused after being saturated with water. Silica gel, high-purity grade can provide a non-toxic, inert aquatic environment for embedded cells, allowing nutrients, oxygen and metabolic waste to diffuse freely and blocking external pollution, thereby maintaining the activity of fibroblasts and epithelial cells .

HY-W040186

1-Naphthenyl phosphate hydrate sodium

Biochemical Assay Reagents

1-Naphthenyl phosphate hydrate sodium is commonly used as a flame retardant for various materials such as plastics, textiles, and construction materials. In addition, its potential use as a corrosion inhibitor and as an ingredient in fertilizers and detergents has been investigated. Its hydrated form contains variable amounts of water molecules, which affects its physical properties and applications.

HY-B1521B

Aluminum hydroxide (0.1 μm)	Biochemical Assay Reagents
Aluminum hydroxide (0.1 μm) is a nano-sized aluminum hydroxide flame retardant with a particle size of approximately 100 nm. Aluminum hydroxide (0.1 μm) can be used in flame-retardant composite materials and improves mechanical properties and processing flowability.

HY-B1521A

Aluminum hydroxide (0.03 μm)	Biochemical Assay Reagents
Aluminum hydroxide (0.03 μm) is a nano-sized aluminum hydroxide flame retardant with a particle size of approximately 30 nm. Aluminum hydroxide (0.03 μm) can be used in flame-retardant composite materials and improves mechanical properties and processing flowability.

HY-W011086R

Tri-O-tolyl phosphate (Standard)

Tri-O-cresyl phosphate (Standard); TOTP (Standard)

Biochemical Assay Reagents

Tri-O-tolyl phosphate (Tri-O-cresyl phosphate; TOTP) (Standard) is an analytical standard of Tri-O-tolyl phosphate (HY-W011086). This product is intended for research and analytical applications. Tri-O-tolyl phosphate is an aryl phosphate compounds commonly utilized as flame retardants and lubricant additives across various industrie. Tri-O-tolyl phosphate has neurotoxicity and reproductive toxicity, decreasing cell viability, inhibiting cell proliferation, triggering cell cycle arrest, induceing apoptosis, causing mitochondrial dysfunction, disrupts calcium homeostasis .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N2296

(2R,3R)-3,7-Dihydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-en-1-yl)chroman-4-one	Flavanonols Flavonoids Classification of Application Fields Leguminosae Other Diseases Phenols Polyphenols Sophora flavescens Aiton Plants Disease Research Fields Source Classification	Others
(2R,3R)-3,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone can be used in a flame retardant for transparent polycarbonate products or in elevator illumination devices research .

HY-141728

Bis(1-chloro-2-propyl) phosphate BCIPP	Natural Products Disease markers Endogenous metabolite Source Classification	Endogenous Metabolite
Bis(1-chloro-2-propyl) phosphate (BCIPP) is a metabolite of organophosphate flame retardants (OPFR) that may alter energy metabolism by influencing the levels of steroid hormones, such as cortisol and cortisone. Bis(1-chloro-2-propyl) phosphate holds potential for research on metabolism-related diseases caused by environmental exposure .

Cat. No.	Product Name	Chemical Structure

HY-107859S

Tris(2-chloroethyl)phosphate-d12

Tris(2-chloroethyl)phosphate-d₁₂ is the deuterium labeled Tris(β-chloroethyl) phosphate. Tris(2-chloroethyl) phosphate is a widely used organic phosphorus flame retardant, mainly used as a plasticizer. Tris(2-chloroethyl) phosphate has orally active hepatotoxicity, inducing an increase in reactive oxygen species (ROS) and calcium ions (Ca²⁺) influx, a decrease in mitochondrial membrane potential (△Ψm), and causing DNA damage and cell apoptosis. Tris(2-chloroethyl) phosphate directly binds to FXR, inducing obesity and the formation of fatty liver in mice. Chloroethyl) phosphate activates the TLR4/NF-κB pathway, triggering liver inflammation.

HY-Y1322S

Triphenyl phosphate-d15

Triphenyl phosphate-d₁₅ is the deuterium labeled Triphenyl phosphate. Triphenyl phosphate is an orally active, blood-brain barrier-permeable aryl organophosphate flame retardant and endocrine disruptor. Triphenyl phosphate disrupts mitochondrial dynamic balance through oxidative stress, induces excessive mitophagy and apoptosis, and ultimately leads to myocardial fibrosis. In the brain, Triphenyl phosphate activates the NF-κB inflammatory pathway by disrupting the gut microbiota, alters tryptophan metabolism and elevates neurotoxins, thereby inducing anxiety- and depression-like behaviors. In the skeletal and reproductive systems, Triphenyl phosphate inhibits osteoblast differentiation and induces germ cell apoptosis by suppressing the MAPK/ERK pathway and activating the JNK signal, respectively. In adipose and placental tissues, Triphenyl phosphate promotes lipid accumulation by activating the PI3K/AKT-PPARγ axis, and disrupts placental metabolism via the MAOA/ROS/NF-κB cascade, impairing neurodevelopment of offspring.

HY-W722115

5-HO-Ehdpp-d10
5-HO-Ehdpp-d₁₀ is the deuterium labeled 5-HO-Ehdpp (HY-W722114). 5-HO-Ehdpp (5-OH-EHDPP) is a flame retardant.

HY-Y1155S

Hexamethylphosphoramide-d18

Hexamethylphosphoramide-d₁₈ is the deuterium labeled Hexamethylphosphoramide (HY-Y1155). Hexamethylphosphoramide is an orally active polar aprotic solvent, flame retardant additive, and carcinogen. Hexamethylphosphoramide undergoes cytochrome P-450-mediated N-demethylation to Formaldehyde. Hexamethylphosphoramide induces DNA-protein crosslinks. Hexamethylphosphoramide has been linked to nasal tumors (squamous cell carcinoma, adenoid squamous cell carcinoma), squamous metaplasia, rhinitis, tracheitis, and reversible and irreversible infertility .

HY-W653929

Bis(1-chloro-2-propyl) phosphate-d12

Bis(1-chloro-2-propyl) phosphate-d₁₂ is deuterium labeled Bis(1-chloro-2-propyl) phosphate. Bis(1-chloro-2-propyl) phosphate (BCIPP) is a metabolite of organophosphate flame retardants (OPFR) that may alter energy metabolism by influencing the levels of steroid hormones, such as cortisol and cortisone. Bis(1-chloro-2-propyl) phosphate holds potential for research on metabolism-related diseases caused by environmental exposure .

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MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
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Flame Retardant

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Biochemical Assay Reagents

NaturalProducts

Isotope-Labeled Compounds

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