33 Results for "

LRP1

" in MedChemExpress (MCE) Product Catalog:
Products (33)

33 Results for "LRP1" in MCE Product Catalog:

  • Isoforms Recommended:
5
5 Cited Publications
Cat. No.: HY-100447
CAS No.: 1103926-82-4
Purity:  98.97%
Target:  

PAI-1

Research Areas:  

Cardiovascular Disease Cancer

TM5275 sodium can inhibit the interaction between PAI-1 and LRP1.
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3
3 Cited Publications
Cat. No.: HY-P702520
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: LRP1; Apolipoprotein E Receptor; Prev. A2MR; TbetaR-V/LRP-1/IGFBP-3 Receptor; Prev. APR; Type V Tgf-Beta Receptor; APOER; Alternative Protein LRP1; Alpha-2-Macroglobulin Receptor; CD91 Antigen; IGFBP3R1; LRP1 Protein; IGFBP-3R; IGFBP3R; LRP1A; TGFBR5; CD9
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P704765
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LRP1; Apolipoprotein E Receptor; Prev. A2MR; TbetaR-V/LRP-1/IGFBP-3 Receptor; Prev. APR; Type V Tgf-Beta Receptor; APOER; Alternative Protein LRP1; Alpha-2-Macroglobulin Receptor; CD91 Antigen; IGFBP3R1; LRP1 Protein; IGFBP-3R; IGFBP3R; LRP1A; TGFBR5; CD9
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P704766
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LRP1; Apolipoprotein E Receptor; Prev. A2MR; TbetaR-V/LRP-1/IGFBP-3 Receptor; Prev. APR; Type V Tgf-Beta Receptor; APOER; Alternative Protein LRP1; Alpha-2-Macroglobulin Receptor; CD91 Antigen; IGFBP3R1; LRP1 Protein; IGFBP-3R; IGFBP3R; LRP1A; TGFBR5; CD9
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P704767
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: LRP1; Apolipoprotein E Receptor; Prev. A2MR; TbetaR-V/LRP-1/IGFBP-3 Receptor; Prev. APR; Type V Tgf-Beta Receptor; APOER; Alternative Protein LRP1; Alpha-2-Macroglobulin Receptor; CD91 Antigen; IGFBP3R1; LRP1 Protein; IGFBP-3R; IGFBP3R; LRP1A; TGFBR5; CD9
Species:  
Source:  
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1
1 Cited Publications
Cat. No.: HY-P80746
Synonyms: A2MR; alpha 2MR; Alpha 2 macroglobulin receptor; CD91; APR; LRP1; LRP85; TGFBR5

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P4073
CAS No.: 1075214-55-9
Synonyms: GRN1005; Paclitaxel trevatide
Research Areas:  

Cancer

ANG1005 (Paclitaxel trevatide) is a brain-penetrating peptide-drug conjugate. ANG1005, a taxane derivative, consists of three paclitaxel (HY-B0015) molecules covalently linked to Angiopep-2, designed to cross the blood-brain and blood-cerebrospinal barriers and to penetrate malignant cells via low density lipoprotein receptor-related protein (LRP1) transport system [1] .
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Cat. No.: HY-P10502
CAS No.: 2378836-93-0
Target:  

LDLR

Research Areas:  

Infection

L57 is a low-density lipoprotein receptor-related protein 1 (LRP1)-binding peptide. L57 exhibits high affinity for LRP1, with an EC50 of 45 nM. L57 possesses blood-brain barrier (BBB) permeability and plasma stability. L57 can serve as a carrier for central nervous system drug delivery [1].
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Cat. No.: HY-P990202

Target:  

LDLR

Research Areas:  

Neurological Disease

Anti-Mouse/Rat/Human LRP1/CD91 Antibody (11H4) is a mouse-derived IgG1 κ type antibody, targeting to mouse/rat/human LRP1/CD91. Anti-Mouse/Rat/Human LRP1/CD91 Antibody (11H4) binds to the β chain of LRP1. Anti-Mouse/Rat/Human LRP1/CD91 Antibody (11H4) can be used for western blot (WB) and other detections [1].
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Cat. No.: HY-P10502A
Target:  

LDLR

Research Areas:  

Others

L57 acetate is a Low-density lipoprotein receptor-related protein 1 (LRP1)-binding peptide. L57 acetate exhibits high affinity to LRP1 with Ki of 45 nM. L57 acetate exhibits blood-brain barrier (BBB) permeability and plasma stability. L57 acetate can be utilized as the carrier for CNS drug delivery [1].
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Cat. No.: HY-RS23105
Research Areas:  

Others

Lrp1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Lrp1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-172699
DSPE-PEG2000-ANG is a conjugate of DSPE-PEG2000-MAL and Angiopep-2. Angiopep-2 is a peptide ligand that targets LRP-1. DSPE-PEG2000-ANG is used to synthesize gadolinium-boron bifunctionalized lipid nanoparticles BPA-F&DOTA-Gd@LIPO-ANG with blood-brain barrier and glioma targeting properties [1].
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Cat. No.: HY-172699A
DSPE-PEG3400-ANG is a PEG compound which composed of DSPE and a dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high LRP1 binding efficiency and has been used for glioma-targeting delivery. DSPE-PEG3400-ANG can be used for drug delivery [1].
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Cat. No.: HY-N9454
CAS No.: 91893-83-3
Garcinoic acid is an orally active anti-inflammatory agent that crosses the blood-brain barrier. Garcinoic acid also enhances efferocytosis and enzyme/receptor regulation, and selectively inhibits human COX-2, porcine α-amylase, Saccharomyces cerevisiae α-glucosidase and human DNA polymerase β (IC50=11 μM), as well as activates human PXR. Garcinoic acid enhances macrophage efferocytosis via receptors such as MerTK and LRP-1, and promotes the production of pro-resolving lipid mediators. Garcinoic acid inhibits NF-κB activation and pro-inflammatory cytokine secretion, interferes with aggregation, downregulates NLRP3 inflammasome activity, and binds to targets including CD44 and EGFR to inhibit leukemia cell proliferation. The pharmacological activities of Garcinoic acid, such as antioxidant, anti-inflammatory and lipid metabolism-regulating effects, are widely used in studies related to various diseases including atherosclerosis, Alzheimer's disease, type 2 diabetes, inflammatory bowel disease and viral pneumonia [1] .
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Cat. No.: HY-RS07792
Research Areas:  

Others

LRP1 Human Pre-designed siRNA Set A contains three designed siRNAs for LRP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS16670
Research Areas:  

Others

Lrp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lrp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-179459
CAS No.: 1210357-06-4
Target:  

Wnt LDLR Amyloid-β

Research Areas:  

Neurological Disease

SJ-300 is a potent and selective, orally active and brain-penetrat DKK3-LRP1 interaction inhibitor. SJ-300 restores clearance in AD models. SJ 300 binds to mLRPIV with a Kd of 7.9 μM, inhibits the DKK3 mLRPIV complex with an IC50 of 3.2 μM, and does not disrupt the binding of to LRP1. SJ 300 rescues cognitive function and ameliorates neuropathology ( plaque reduction ≈ 73.3 %) in vivo. SJ 300 can be employed for research in Alzheimer’s disease [1].
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Cat. No.: HY-P11413
CAS No.: 139446-70-1
PAI-1 is a serine protease inhibitor (SERPIN). PAI-1 binds to and irreversibly inhibits uPA, tPA and furin; it also interacts with vitronectin, α1-acid glycoprotein, CRT, TLR4, proteasome α-3 subunit, uPAR, LRP1, Integrin αvβ3 and thrombin. PAI-1 regulates fibrinolysis, extracellular matrix turnover, cell migration, angiogenesis, inflammatory response and tissue remodeling; it mediates epithelial-mesenchymal transition (EMT)/endothelial-mesenchymal transition (EndMT), apoptosis and thrombus stabilization. PAI-1 can be used in research related to sepsis, acute lung injury, cardiovascular diseases, tissue fibrosis, diabetic nephropathy, obstructive nephropathy and non-insulin-dependent diabetes mellitus [1] .
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Cat. No.: HY-P10911
CAS No.: 2314338-36-6
Target:  

LDLR

Research Areas:  

Others

IETP2 targets low-density lipoprotein receptor-related protein 1 (LRP1) with a KD of 738 nM and can be used for drug- and imaging agents delivery across the blood-labyrinth barrier (BLB) [1].
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Cat. No.: HY-172700
DSPE-PEG5000-ANG is a PEG compound which composed of DSPE and a dual-targeting ligand (Angiopep-2, ANG). ANG exhibits high LRP1 binding efficiency and has been used for glioma-targeting delivery. DSPE-PEG5000-ANG can be used for drug delivery [1].
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