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Results for "

Melanin biosynthesis inhibitor

" in MedChemExpress (MCE) Product Catalog:

20

Inhibitors & Agonists

10

Natural
Products

1

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-126052
    Gnetol

    		COX Tyrosinase HDAC Metabolic Disease Cancer
    Gnetol is a phenolic compound isolated from the root of Gnetum montanum . Gnetol potently inhibits COX-1 (IC50 of 0.78 μM) and HDAC. Gnetol is a potent tyrosinase inhibitor with an IC50 of 4.5 μM for murine tyrosinase and suppresses melanin biosynthesis. Gnetol has antioxidant, antiproliferative, anticancer and hepatoprotective activity. Gnetol also possesses concentration-dependent α-Amylase, α-glucosidase, and adipogenesis activities .
    Gnetol
  • HY-B0848
    Tricyclazole
    2 Publications Verification

    		 Environmental Pollutants Bacterial Infection Metabolic Disease
    Tricyclazole is a pentaketone melanin biosynthesis inhibitor and a unique fungicide for controlling rice blast. Tricyclazole alters the structure and function of fungal cell walls, reduces fungal pathogenicity and penetration, and causes dose-dependent liver damage in animals .
    Tricyclazole
  • HY-N6243
    Veratrosine

    		Fungal Infection
    Veratrosine is a Trihydroxynapthalene reductase (THR) inhibitor and fungal plant pathogen inhibitor. Veratrosine interacts with THR, an enzyme in the DHN melanin biosynthesis pathway of Curvularia lunata. Veratrosine can be used for the research of leaf blight of rice, brown spot of rice, and blast disease of foxtail millet .
    Veratrosine
  • HY-N9521
    3-O-β-D-Glucopyranosyl(1→2)-[a-Lrhamnopyranosyl(1→3)]-β-D-glucopyranosyl 28-O-β-D-glucuronopyranoside

    		Others Cancer
    3-O-β-D-Glucopyranosyl(1→2)-[a-Lrhamnopyranosyl(1→3)]-β-D-glucopyranosyl 28-O-β-D-glucuronopyranoside, a saponin, is isolated from Polaskia chichipe Backbg. 3-O-β-D-Glucopyranosyl(1→2)-[a-Lrhamnopyranosyl(1→3)]-β-D-glucopyranosyl 28-O-β-D-glucuronopyranoside shows ability to inhibit melanin biosynthesis by B16 melanoma cell with inhibitory activity 84.2% at 100μM[1].
    3-O-β-D-Glucopyranosyl(1→2)-[a-Lrhamnopyranosyl(1→3)]-β-D-glucopyranosyl 28-O-β-D-glucuronopyranoside
  • HY-W775186
    Tolprocarb

    		Fungal Infection
    Tolprocarb is an oomyces fungicide, which has a strong inhibitory effect on rice blast fungus Magnaporthe grisea by inhibiting polyketide synthase in melanin synthesis pathway .
    Tolprocarb
  • HY-161241
    Tyrosinase-IN-23

    		Tyrosinase Cancer
    Tyrosinase-IN-23 (Compd 11m) is a tyrosinase inhibitor with an IC50 of 55.39±4.93 µM. Tyrosinase-IN-23 can be used for research of melanin biosynthesis .
    Tyrosinase-IN-23
  • HY-N14240
    Melanocin A

    		Melanocortin Receptor Cancer
    Melanocin A is a Melanin biosynthesis inhibitor. Melanocin A inhibits the biosynthesis of melanin and tyrosinase (IC50 is 9.0 nM, MIC is 0.9 μM). Melanocin A also has antioxidant effect .
    Melanocin A
  • HY-163326
    Tyrosinase-IN-25

    		Tyrosinase Cancer
    Tyrosinase-IN-25 (compound 1l) is an inhibitor of tyrosinase and melanin biosynthesis in human melanoma cells .
    Tyrosinase-IN-25
  • HY-W725641
    Tricyclazole-d3

    		Bacterial Infection
    Tricyclazole-d3 is the deuterium labeled Tricyclazole. Tricyclazole is a pentaketide-derived melanin biosynthesis inhibitor.
    Tricyclazole-d3
  • HY-N13922
    Scytalol A

    		Melanocortin Receptor Infection
    Scytalol A selectively inhibits biosynthesis of dihydroxynaphthalene melanin in Lachnellula sp. A32-89, but does not inhibit the growth of the strain .
    Scytalol A
  • HY-N14245
    Melanoxazal

    		Melanocortin Receptor Cancer
    Melanoxazal is a Melanin biosynthesis inhibitor. Melanoxazal can inhibit melanin formation in the silkworm larva hemolymph (IC50 is 30.1 μg/mL), and also has stronger inhibitory effect against mushroom tyrosinase (IC50 is 4.2 μg/mL), but it has no antimicrobial effect .
    Melanoxazal
  • HY-N12431
    Machilin A

    		Others Cancer
    Machilin A is a lignan isolated from the methanolic extract of Phoebe bark. Machilin A inhibits melanin biosynthesis in B-16 mouse melanoma cells with an IC50 of 39.9 μM.
    Machilin A
  • HY-B0848R
    Tricyclazole (Standard)

    		Reference Standards Bacterial Infection
    Tricyclazole (Standard) is the analytical standard of Tricyclazole. This product is intended for research and analytical applications. Tricyclazole is a pentaketide-derived melanin biosynthesis inhibitor and a unique fungicide for control of Pyricularia oryzae on rice .
    Tricyclazole (Standard)
  • HY-111898
    Epirosmanol

    		Others Cancer
    Epirosmanol is a nature diterpene lactone from S. officinalis. Epirosmanol shows anti-cancer activity and inhibits melanin biosynthesis against melanoma cells. Epirosmanol also exhibits DPPH radical scavenging activity .
    Epirosmanol
  • HY-143449
    Tyrosinase-IN-2

    		Tyrosinase Others
    Tyrosinase-IN-2 (compound 67) is a potent inhibitor of tyrosinase. Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting catalytic step in the melanin biosynthesis and enzymatic browning. Tyrosinase-IN-2 has the potential for the research of skin whitening agents and food preservatives .
    Tyrosinase-IN-2
  • HY-143448
    Tyrosinase-IN-1

    		Tyrosinase Others
    Tyrosinase-IN-1 (compound 90) is a potent inhibitor of tyrosinase. Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting catalytic step in the melanin biosynthesis and enzymatic browning. Tyrosinase-IN-1 has the potential for the research of skin whitening agents and food preservatives .
    Tyrosinase-IN-1
  • HY-143450
    Tyrosinase-IN-3

    		Tyrosinase Others
    Tyrosinase-IN-3 (compound 54) is a potent inhibitor of tyrosinase. Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting catalytic step in the melanin biosynthesis and enzymatic browning. Tyrosinase-IN-3 has the potential for the research of skin whitening agents and food preservatives .
    Tyrosinase-IN-3
  • HY-143451
    Tyrosinase-IN-4

    		Tyrosinase Others
    Tyrosinase-IN-4 (compound 34) is a potent inhibitor of tyrosinase. Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting catalytic step in the melanin biosynthesis and enzymatic browning. Tyrosinase-IN-4 has the potential for the research of skin whitening agents and food preservatives .
    Tyrosinase-IN-4
  • HY-N14272
    Melanocin B

    		Others Metabolic Disease
    Melanocin B does not inhibit the biosynthesis of melanin and tyrosinase. Melanocin B has antioxidant effect .
    Melanocin B
  • HY-N14241
    Melanocin C

    		Others Metabolic Disease
    Melanocin C does not inhibit the biosynthesis of melanin and tyrosinase. Melanocin C has antioxidant effect .
    Melanocin C

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