2. Anti-infection
  3. Fungal
  4. Veratrosine

Veratrosine is a Trihydroxynapthalene reductase (THR) inhibitor and fungal plant pathogen inhibitor. Veratrosine interacts with THR, an enzyme in the DHN melanin biosynthesis pathway of Curvularia lunata. Veratrosine can be used for the research of leaf blight of rice, brown spot of rice, and blast disease of foxtail millet.

For research use only. We do not sell to patients.

Veratrosine

Veratrosine Chemical Structure

CAS No. : 475-00-3

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Veratrosine Related Antibodies

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Description

Veratrosine is a Trihydroxynapthalene reductase (THR) inhibitor and fungal plant pathogen inhibitor. Veratrosine interacts with THR, an enzyme in the DHN melanin biosynthesis pathway of Curvularia lunata. Veratrosine can be used for the research of leaf blight of rice, brown spot of rice, and blast disease of foxtail millet[1].

In Vitro

Veratrosine binds to beta-tubulin of Curvularia lunata with a binding affinity of -7.41 kcal/mol[1].
Veratrosine binds to trihydroxynaphthalene reductase of Curvularia lunata with a binding affinity of -12.4 kcal/mol[1].
Veratrosine binds to polyketide synthase of Pyricularia setariae with a binding affinity of -7.67 kcal/mol[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Veratrosine Related Antibodies
Molecular Weight

571.74

Formula

C33H49NO7
CAS No.
Appearance

Solid

Color

Off-white to yellow

SMILES

C[C@@]12[C@]3([H])[C@](CC=C1C[C@@H](O[C@]4([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)CO)CC2)([H])C5=CC=C([C@@H]([C@@]6([H])[C@@H](C[C@H](C)CN6)O)C)C(C)=C5C3
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (174.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7490 mL 8.7452 mL 17.4905 mL
5 mM 0.3498 mL 1.7490 mL 3.4981 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.0%

SDS (252 KB)

COA (247 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7490 mL 8.7452 mL 17.4905 mL 43.7262 mL
5 mM 0.3498 mL 1.7490 mL 3.4981 mL 8.7452 mL
10 mM 0.1749 mL 0.8745 mL 1.7490 mL 4.3726 mL
15 mM 0.1166 mL 0.5830 mL 1.1660 mL 2.9151 mL
20 mM 0.0875 mL 0.4373 mL 0.8745 mL 2.1863 mL
25 mM 0.0700 mL 0.3498 mL 0.6996 mL 1.7490 mL
30 mM 0.0583 mL 0.2915 mL 0.5830 mL 1.4575 mL
40 mM 0.0437 mL 0.2186 mL 0.4373 mL 1.0932 mL
50 mM 0.0350 mL 0.1749 mL 0.3498 mL 0.8745 mL
60 mM 0.0292 mL 0.1458 mL 0.2915 mL 0.7288 mL
80 mM 0.0219 mL 0.1093 mL 0.2186 mL 0.5466 mL
100 mM 0.0175 mL 0.0875 mL 0.1749 mL 0.4373 mL
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Veratrosine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Veratrosine475-00-3Fungalpolyketide synthaseCurvularia lunataDHN melanin biosynthesis pathwayTrihydroxynapthalene reductasebeta-tubulinblast disease of foxtail millettrihydroxynaphthalene reductasebrown spot of ricePyricularia setariaeleaf blight of riceInhibitorinhibitorinhibit

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