Tyrosinase-IN-2
Based on 1 Customer Validation
Tyrosinase-IN-2 (compound 67) is a potent inhibitor of tyrosinase. Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting catalytic step in the melanin biosynthesis and enzymatic browning. Tyrosinase-IN-2 has the potential for the research of skin whitening agents and food preservatives.
For research use only. We do not sell to patients.
- Purity: 99.71%
- CAS No.: 180864-33-9
- Formula: C8H8N4O2S
- Molecular Weight:224.24
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Vero | IC50 |
0.5 mM
Compound: 2b
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Compound tested on intracellular parasites Toxoplasma gondii in vero cells after 24 h
Compound tested on intracellular parasites Toxoplasma gondii in vero cells after 24 h
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[PMID: 15863319] |
| Vero | IC50 |
1.5 mM
Compound: 2b
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Compound tested on vero cells infected with Toxoplasma gondii after 24 h
Compound tested on vero cells infected with Toxoplasma gondii after 24 h
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[PMID: 15863319] |
Chemical Information
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CAS No. 180864-33-9
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Appearance Solid
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Molecular Weight 224.24
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Formula C8H8N4O2S
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Color Light yellow to yellow
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SMILES
O=[N+](C1=CC=C(/C=N/NC(N)=S)C=C1)[O-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 125 mg/mL (557.44 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.4595 mL | 22.2975 mL | 44.5951 mL | 111.4877 mL |
| 5 mM | 0.8919 mL | 4.4595 mL | 8.9190 mL | 22.2975 mL | |
| 10 mM | 0.4460 mL | 2.2298 mL | 4.4595 mL | 11.1488 mL | |
| 15 mM | 0.2973 mL | 1.4865 mL | 2.9730 mL | 7.4325 mL | |
| 20 mM | 0.2230 mL | 1.1149 mL | 2.2298 mL | 5.5744 mL | |
| 25 mM | 0.1784 mL | 0.8919 mL | 1.7838 mL | 4.4595 mL | |
| 30 mM | 0.1487 mL | 0.7433 mL | 1.4865 mL | 3.7163 mL | |
| 40 mM | 0.1115 mL | 0.5574 mL | 1.1149 mL | 2.7872 mL | |
| 50 mM | 0.0892 mL | 0.4460 mL | 0.8919 mL | 2.2298 mL | |
| 60 mM | 0.0743 mL | 0.3716 mL | 0.7433 mL | 1.8581 mL | |
| 80 mM | 0.0557 mL | 0.2787 mL | 0.5574 mL | 1.3936 mL | |
| 100 mM | 0.0446 mL | 0.2230 mL | 0.4460 mL | 1.1149 mL |
Tyrosinase-IN-2 Related Classifications
HY-143449 Related Classifications
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