Tyrosinase-IN-4
Tyrosinase-IN-4 (compound 34) is a potent inhibitor of tyrosinase. Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting catalytic step in the melanin biosynthesis and enzymatic browning. Tyrosinase-IN-4 has the potential for the research of skin whitening agents and food preservatives.
For research use only. We do not sell to patients.
- CAS No.: 19275-70-8
- Formula: C15H9ClO3
- Molecular Weight:272.68
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
6.8 μM
Compound: 4m
|
Cytotoxicity against human HCT116 cells assessed as cell viability after 48 hrs by MTT assay
Cytotoxicity against human HCT116 cells assessed as cell viability after 48 hrs by MTT assay
|
[PMID: 23771043] |
| HL-60 | IC50 |
102 μM
Compound: 1
|
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
Cytotoxicity against human HL60 cells after 72 hrs by MTT assay
|
[PMID: 25014747] |
Chemical Information
-
CAS No. 19275-70-8
-
Molecular Weight 272.68
-
Formula C15H9ClO3
-
SMILES
O=C1C(O)=C(C2=CC=C(Cl)C=C2)OC3=C1C=CC=C3
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)